CV

Education

1977 MD degree, 110/110 cum laude (top 3%), Medical School, University of Genoa, Italy

1980 Specialization in Haematology 50/50 cum laude Medical School, Univ. of Genoa

Current positions

2000- today Professor of Molecular Biology, Università Vita Salute San Raffaele (UniSR) Milano

1990-today Group leader, San Raffaele Scientific Institute (SRSI), Milan

Previous positions

2008-2014 Director, Division of Genetics and Cell Biology, SRSI, Milano

2005-2007 Dean of the School of Medicine, UniSR, Milano

1998-2007 Deputy Director, Dept. of Functional Genomics and Molecular Biology, SRSI, Milano

1987-1990 Associate Professor, Immunogenetics, National Cancer Center, Genoa Italy

1986-1987 Visiting Investigator, Laboratory of Molecular Biology, Cambridge, UK

1982-1986 Assistant Professor, Molecular Biology, National Cancer Center, Genoa Italy

1980-1982 Assistant Professor, Immunology and Transplantation, University of Genoa, Italy

1978-1979 Post Doc, Immunochemistry, Memorial Sloan Kettering Cancer Center, New York, USA

Fellowships and awards

2008 (Feb-Dec) Visiting professor, Institut Curie, Paris (France)

2006 (Oct-Nov) Visiting professor, Tokyo University (Japan)

1999 (Jan-Feb) Visiting professor, New South Wales University (Australia)

1986-1987 EMBO long-term fellow

1982-1984 Recipient of a NATO cooperation grant

Teaching activities and supervision of graduate students and post-doctoral fellows

Coordinator of the Course of Molecular Cell Biology (UniSR, Medical School) since 1998

14 graduate students trained over the last 10 years

12 postdoctoral fellows trained over the last 10 years

Honours & Professional Societies

Elected Member of the European Molecular Biology Organisation (EMBO), 1992

Italian Associations of Cell Biology and Development (ABCD, twice in the steering committee)

Italian Society of Biochemistry and Molecular Biology (SIBMB)

American Society of Cell Biology (ASCB)

American Society of Biochemistry and Molecular Biology (ASBMB)

Organisation of Scientific Meetings

2007 Chair of the ELSO Meeting (Dresden, Germany)

2008 II Gordon Conference, Thiol-based Redox Regulation and Signalling 2008 Il Ciocco (IT) Vice-Chair

2010 III Gordon Conference, Thiol-based Redox Regulation and Signalling 2010 Il Ciocco (IT) Chair

2011 ETH Conference Quality Control: Folding and Degradation of Proteins in the Endoplasmic

Reticulum Ascona (Switzerland) 2011 Co-Chair

Institutional responsibilities

2001-today Faculty member, UniSR Medical School

2004-today Faculty member, PostGraduate course in Cell and Molecular Biology UniSR, IT

1994-2004 Faculty member, PostGraduate course in Cell and Molecular Biology, Open Univ., UK

2004-2007 Chair, EMBO Science and Society Committee

2002-2004 Member, EMBO Science and Society Committee

1998-2006 Co-Founder and member of the Steering Committee of ELSO

1993-1996 Member of the EMBO Course and Workshop Committee

1992 Founder and member of the Steering committee of the Eur. Network of Immunology Institutes

Commissions of trust

-Editor, The EMBO Journal (1998-present); EMBO Reports (1998-2010); The Journal of Biological Chemistry (2001-2006); PathoGenetics (2008-2011); Antioxidant Redox Signaling (2010-present); Nature Scientific Reports (2013-present)

-Referee for most Molecular Cell Biology and Immunology journals, including: Nature, Science, Cell, Mol Cell, Immunity, Curr. Biol, PNAS, EMBO J. etc

-Member of many evaluation committees, including: Academy of Finland; Medical Research Council, UK (International scientific committee 2001-2005); Austrian Research Minister, FWF; Israeli Science Foundation: Spanish Minister of Science and Education; National Institutes for Health; Swiss Science Foundation; Agencie Nationale de la Recherche (FR); Telethon; Wellcome Trust; Italian Ministries of Health and of University and Research; Consiglio Nazionale Ricerche

-Consultant for small, medium and big enterprises, including Alchera Group, Italfarmaco, Roche, Shell

-Co-founder of a small biotech company, Xeptagen.

-Scientific Advisory Board, Enciclopedia Italiana Treccani (1994-1998) and Editor of KOS a magazine merging science, medicine and culture (1998-2008)

-Founder (2004) and member ever since of the Steering Committee of Bergamo Scienza (a popular science festival that in 2013 totalled over 100,000 visitors)

Major collaborations

2014-today J. Buchner, Munchen GE. Molecular mechanisms of IgM polymerization

2013-today A. Luini, Naples, I. Redox control of KDEL receptor signaling

2011-today R. Rizzuto & P. Pinton (Padua-Ferrara, IT). Control of Ca²⁺ and redox signaling by Ero1

2010-today K. Nagata, Kyoto Univ. JP. Intracellular transport of peroxiredoxin 4

2009-today K. Inaba, Tohoku Univ. JP. Structure of Ero1 and regulation of ERp44

2009-2010 D. Ron, Cambridge Univ. UK Context specific role of CHOP in B cells

2007-2008 P. Cosma, Naples-Barcelona. Control of SUMF1 secretion by ERp44

2007-today C.C. Wang, Chinese Academy of Science. Structure of ERp44, H₂O₂ scavenging by Gpx7.

1999-2003 I. Braakman (Utrecht Univ. NL). Biogenesis and redox control of/in the ER.