Quinn Lab - Publications

Quinn Lab

Electronic actuation of surface-immobilized, pH-responsive DNA nanoswitches.

F. D'Rozario, C. D. Silver, K. E. Dunn, S. D. Quinn, A. M. Tyrrell, C. Walti & S. D. Johnson.

ACS Applied Materials & Interfaces (2026).

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Transitional kinetics between open and closed Rep structures can be tuned by salt via two intermediate states .

J. A. L. Howard et al.

Nucleic Acids Research (2026).

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Detergent-triggered membrane remodelling monitored via intramembrane fluorescence dequenching.

C. M. F. Andrews, C. M. Hofmair, L. Roberts, E. James, K. Morris, K. Kramm, M. C. Leake, Y. Wang & S. D. Quinn.

ACS Omega (2026).

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A DNA scaffold approach facilitates 5' labeling of the SARS-CoV-2 RNA Pseudoknot for Single-Molecule Forster Resonance Energy Transfer Investigation.

S. P. Graham, J. K. Betts, T. D. Craggs, M. C. Leake, C. H. Hill & S. D. Quinn.

ChemPhysChem. e202500568 (2025).

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Nanotechnology-based devices and systems for enhanced sensitivity and efficiency in biomedical applications.

D. Conteduca, C. Kunstmann-Olsen & S. D. Quinn.

Front. Bioeng. Biotechnol. 13.

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Ultrasensitive Alzheimer's disease biomarker detection with nanopillar photonic crystal biosensors.

G. S. Arruda, K. Morris, A. Martins, Y. Wang, S. Sloan-Dennison, D. Graham, S. D. Quinn, E. R. Martins & T. F. Krauss.

Optica. 12, 1587-1596 (2025).

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The urgent and global need for democratized blood-based biomarker diagnostics in Alzheimer's disease.

S. D. Quinn

The Journal of Precision Medicine: Health and Disease, 1, 100002

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Resonant Young's slit interferometer for sensitive detection of low-molecular-weight biomarkers.

Stefanus R. Wijaya, A. Martins, K. Morris, S. D. Quinn & T. F. Krauss.

Biosensors, 15, 50 (2025).

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Multiple intermediates in the detergent-induced fusion of lipid vesicles.

Lara G. Dresser, Casper Kunstmann-Olsen, Donato Conteduca, Christopher M. Hofmair, Nathan Smith, Laura Clark, Steven Johnson, J. Carlos Penedo, Mark C. Leake & Steven D. Quinn.

Communications Materials, 5, 195 (2024).

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Multiplexed near-field optical trapping exploiting anapole states.

Donato Conteduca, Giuseppe Brunetti, Isabel Barth, Steven D. Quinn, Caterina Ciminelli & Thomas F. Krauss.

ACS Nano, 17, 16695-16702 (2023).

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A guide to small fluorescent probes for single-molecule biophysics.

Steven D. Quinn & Mark C. Leake

Chemical Physics Reviews, 4, 011302 (2023).

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Sticker-and-spacer model for amyloid beta condensation and fibrillation.

Jack Connor, Steven D. Quinn & Charley Schaefer.

Frontiers in Molecular Neuroscience, 15, 962526 (2022).

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Crowding-induced morphological changes in synthetic lipid vesicles determined using smFRET

Steven D. Quinn, Lara Dresser, Sarah Graham, Donato Conteduca, Jack Shepherd & Mark C. Leake

Frontiers in Bioengineering and Biotechnology, 10, 958026 (2022).

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Correlating viscosity and molecular crowding with fluorescent nanobeads and molecular probes: in vitro and in vivo.

S. Lecinski, J. W. Shepherd, K. Bunting, L. Dresser, S. D. Quinn, C. MacDonald & M. C. Leake

Interface Focus, 12, 20220042 (2022).

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Ligand-induced transmembrane conformational coupling in monomeric EGFR.

Shwetha Srinivasan, Raju Regmi, Xingcheng Lin, Courtney A. Dreyer, Xuyan Chen, Steven D. Quinn, Wei He, Matthew A. Coleman, Kermit L. Carraway III, Bin Zhang & Gabriela Schlau-Cohen.

Nature Communications, 13, 3709 (2022).

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Tween-20 induces the structural remodelling of single lipid vesicles.

Lara Dresser, Sarah P. Graham, Lisa M. Miller, Charley Schaefer, Donato Conteduca, Steven Johnson, Mark C. Leake & Steven D. Quinn.

J. Phys. Chem. Lett. 13, 5341-5350 (2022).

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Dielectric metasurface for high-precision detection of large unilamellar vesicles

Donato Conteduca, Steven Quinn, Thomas Krauss

J. Opt. 23, 114002 (2021)

Published online: 22 October 2021

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Single-molecule FRET dynamics of molecular motors in an ABEL Trap

Maria Dienerowitz, Jamieson Howard, Steven D. Quinn, Frank Dienerowitz & Mark C. Leake.

Accepted in Methods (2021).

Currently available via arXiv.

Available online: 22 September 2020

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The Mechanism of Vesicle Solubilization by the Detergent Sodium Dodecyl Sulfate

José Juan-Colás, Lara Dresser, Katie Morris, Hugo Lagadou, Rebecca H. Ward, Amy Burns, Steve Tear, Steven Johnson, Mark C. Leake & Steven D. Quinn

Langmuir, In Press (2020)

Published online: 1 September 2020

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Amyloid-β Oligomerization Monitored by Single-Molecule Stepwise Photobleaching

Lara Dresser, Patrick Hunter, Fatima Yendybayeva, Alex L. Hargreaves, Jamieson A. L. Howard, Gareth J. O. Evans, Mark C. Leake & Steven D. Quinn.

Methods, In Press (2020)

Published Online: 13 June 2020

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Unveiling the Multi-Step Solubilization Mechanism of Sub-Micron Size Vesicles by Detergents

Paul A. Dalgarno, José Juan-Colás, Gordon J. Hedley, Lucas Piñeiro, Mercedes Novo, Cibran Perez Gonzalez, Ifor D. W. Samuel, Mark C. Leake, Steven Johnson, Wajih Al-Soufi, J. Carlos Penedo & Steven D. Quinn.

Scientific Reports, 9, 12897 (2019)

Published Online: 9 September 2019

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Single-Molecule Fluorescence Detection of the Epidermal Growth Factor Receptor in Membrane Discs

Steven D. Quinn, Shwetha Srinivasan, Jesse B. Gordon, Wei He, Kermit L. Carraway III, Matthew A. Coleman & Gabriela Schlau-Cohen.

Biochemistry, 58, 286-294 (2019)

Published Online: 19 March 2018

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Optical Detection of Gadolinium(III) Ions via Quantum Dot Aggregation

Steven D. Quinn & Steven W. Magennis

RSC Advances, 7, 24730-24735 (2017)

Published Online: 11 May 2017

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Single-Molecule Fluorescence Detection of a Heparan Sulfate Disaccharide

Charlotte E. Dalton, Steven D. Quinn, Aidan Rafferty, Michael J. Morten, John M. Gardiner & Steven W. Magennis

ChemPhysChem, 17, 3442-3446 (2016)

Published Online: 14 September 2016

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Surface Charge Control of Quantum Dot Photoblinking

Steven D. Quinn, Aidan Rafferty, Emma Dick, Michael J. Morten, Fraser J. Kettles, Chloe Knox, Mark Murrie & Steven W. Magennis.

J. Phys. Chem. C., 120, 19487-19491

Published Online: 8 August 2016

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Morphology-specific inhibition of β-amyloid aggregates by 17β-hydroxysteroid dehydrogenase type 10

Laura Aitken, Steven D. Quinn, Daniel C. Perez-Gonzalez, Ifor D. W. Samuel, J. Carlos Penedo-Esteiro & Frank J. Gunn-Moore.

ChemBioChem, 17, 1029-1037 (2016)

Published Online: 16 March 2016

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The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death

Ryan T Cameron, Steven D Quinn, Lynn S Cairns, Ruth MacLeod, Ifor DW Samuel, Brian O Smith, J Carlos Penedo & George S Baillie

Mol. Cell. Neurosci. 61, 46-55 (2014).

Published Online: 20 May 2014

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Real-time probing of β-amyloid self-assembly and inhibition using fluorescence self-quenching between neighbouring dyes

Steven D. Quinn, Paul A. Dalgarno, Ryan T. Cameron, Gordon J. Hedley, Christian Hacker, John M. Lucocq, George S. Baillie, Ifor D. W. Samuel & J. Carlos Penedo.

Molecular Biosystems, 10, 34-44 (2014)

Published Online: 22 October 2013

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