Our group is in the School of Physics, Engineering and Technology at the University of York. We are a team of highly interdisciplinary scientists working at the cutting-edge of single-molecule biophysics research to detect and investigate the molecular nanoworld of human life and disease.

Our lab is affiliated with the Physics of Life Research Group and the York Biomedical Research Institute.

Our lives have some meaning on a scale of meters, but it’s often impossible to think about ordinary, everyday existence on a scale 1000 times smaller than a fly’s eye - the so-called 'nanosale'. Yet the nanoscale is where proteins and DNA molecules, the building blocks of human life, rule the roost. By zooming into the nanoscale, our goal is to understand how many of the puzzling pathways in human disease work at the smallest possible length scale. 

Our current research combines tools from optics and spectroscopy, biology, chemistry and microscopy to detect and probe the nanoscale interactions associated with Alzheimer's disease. We leverage major technological developments with novel biochemical approaches to more effectively and efficiently drive the search for next-generation diagnostic and therapeutic approaches.