Publications

Preprint

2024

Lydia Green*, Noémie Hamilton*, Marilena Elpidorou, Erica L. Harris, Andrew Douglas, Katrin Ounap, Reza Maroofian, Ailsa MS Rose, Stone Elworthy, Stephen A Renshaw, Elizabeth C Low, Trine Prescott, Kristoffer Soberg, Almunder Al-Maawali, Sana Al-Zuhaib, Amna Al Futaisi, Daniel Calame, Khalid Al-Thihli, Eamonn G Sheridan, Colin A Johnson, John Livingston, Yanick J. Crow, James A Poulter. Biallelic mutation of SUPV3L1 causes an inherited leukodystrophy-associated neurodevelopmental disorder due to aberrant mitochondrial double stranded RNA processing. ResearchSquare 2024 DOI 10.21203/rs.3.rs-4356120/v1. *Contributed equally / Corresponding authors

All Published Articles

2024

Holly A Rutherford, Diogo Candeias, Christopher JA Duncan, Stephen A Renshaw, Noémie Hamilton

Macrophage transplantation rescues RNASET2-deficient leukodystrophy by replacing deficient microglia in a zebrafish model. PNAS. 2024 121 (21) e2321496121. doi: 10.1073/pnas.2321496121. Corresponding author.

2023

Stone Elworthy, Holly A Rutherford, Tomasz K Prajsnar, Noémie Hamilton, Katja Vogt, Stephen A Renshaw, and Alison M Condliffe. Activated PI3K Delta Syndrome-1 mutations cause neutrophilia in zebrafish larvae. Disease Models and Mechanisms. 2023 16(3):dmm049841. doi: 10.1242/dmm.049841.

Noémie Hamilton, Claire Allen and Steven Reynolds. Longitudinal MRI brain studies in adult zebrafish. NMR Biomedicine, 2023 e4891 doi: 10.1002/nbm.4891. Corresponding authors

2022

Holly A. Rutherford, Amy Clarke, Emily V. Chambers, Jessica J. Petts, Euan G. Carson, Hannah M. Isles, Alejandra Duque-Jaramillo, Stephen A Renshaw, Jean-Pierre Levraud, Noémie Hamilton. Immune and neuronal expression of zebrafish endogenous retrovirus. Disease Models and Mechanisms. 2022. 15(4):dmm048921. doi: 10.1242/dmm.048921. Corresponding author

2021

Elisabeth Kugler, Ryan Snodgrass, George Bowley, Karen Plant, Jovana Serbanovic-Canic, Noémie Hamilton, Paul C. Evans, Timothy Chico, Paul Armitage. The effect of absent blood flow on the zebrafish cerebral and trunk vasculature. Vascular Biology. 2021. 29;3(1):1-16.

Hannah M Isles, Catherine A Loynes, Sultan Alasmari, Fu Chuen Kon, Katherine M Henry, Anastasia Kadochnikova, Jack Hales, Clare F Muir, Maria-Cristina Keightley, Visakan Kadirkamanathan, Noémie Hamilton, Graham J Lieschke, Stephen A. Renshaw, Philip M. Elks. Pioneer neutrophils release chromatin within in vivo swarms. eLife. 2021;10:e68755 https://doi.org/10.7554/eLife.68755

Holly A. Rutherford, Paul Kasher, Noémie Hamilton. Dirty fish versus squeaky clean mice: Dissecting interspecies differences between animal models of interferonopathy. Frontiers Immunology, January 2021. https://doi.org/10.3389/fimmu.2020.623650. Corresponding author

2020

Noémie Hamilton, Holly A. Rutherford, Hannah M. Isles, Jessica J Petts, Marco Henneke, Jutta Gärtner, Mark Dunning, Stephen A Renshaw. The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2‐deficient leukoencephalopathy. 2020. Glia. 68 (7): 1531-1545. DOI: 10.1002/glia.23829. Corresponding author

Thomas Weber, Lars Schlotawa, Roland Dosch, Noémie Hamilton, Jens Kaiser, Stina Schiller, Britta Wenske, Jutta Gärtner, Marco Henneke. Zebrafish Disease Model of Human RNASET2 Deficient Cystic Leukoencephalopathy Displays Abnormalities in Early Microglia. 2020. Biology Open. 9: bio049239

2019

Holly Rutherford and Noémie Hamilton. Animal Models of Leukodystrophy: A new perspective for the development of therapies. 2019. FEBS. 286 4176–4191. Corresponding author

2018

Noémie Hamilton, Ian Sabroe and SA Renshaw. A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models. 2018. F1000Research NC3Rs Gateway. 7:594 Corresponding author

William T. Stockdale, Madeleine E. Lemieux, Abigail C. Killen, Juanjuan Zhao, Zhilian Hu, Joey Riepsaame, Noémie Hamilton, Tetsuhiro Kudoh, Paul R. Riley, Ronny van Aerle, Yoshiyuki Yamamoto and Mathilda T. M. Mommersteeg. Heart Regeneration in the Mexican Cavefish. 2018. Cell Report. 25(8):1997-2007.

Xiaoyun Ren*, Noémie Hamilton*, Ferenc Mueller, Yoshiyuki Yamamoto. Cellular rearrangement of the prechordal plate contributes to eye degeneration in the cavefish. 2018. Developmental Biology. 441(2):221-234.  *Authors contributed equally

Laranjeiro R, Tamai T, Letton W, Noémie Hamilton, Whitmore D. Circadian clock synchronization of the cell cycle in zebrafish occurs through a gating mechanism rather than a period-phase locking process. 2018 . Journal of Biological Rhythms. 33(2):137-150.

2015 and before

Noémie Hamilton, Diez De Cerio N, Whitmore D. Impaired light detection of the circadian clock in a zebrafish melanoma model. 2015. Cell Cycle. 14(8):1232-41. Corresponding author

Noémie Haud, Kara F, Diekmann S, Henneke M, Willer JR, Hillwig MH, Gregg RB, MacIntosh GC, Gärtner J, Alia A, and Hurlstone A. RNase T2 mutant zebrafish model familial cystic leukoencephalopathy and reveal a role for RNase T2 in degrading ribosomal RNA. 2011. PNAS. 108(3) 1099-1103.

Alia A, Kara F, Noémie Hamilton and Hurlstone A. Ultra High Field Magnetic Resonance Microimaging in Zebrafish Model of Cystic Leukoencephalopathy. Proc. Intl. Soc. Mag. Reson. Med. 2011. 19:4148. Conference paper.

Henneke M, Diekmann S, Noémie Haud, Alia A, Hurlstone A, Gärtner J. Rnaset2-Deficient Cystic Leukoencephalopathy Is a New Lysosomal Disorder. 2010 Journal of Inherited Metabolic Disease. Conference paper

Henneke M, Diekmann S, Noémie Haud , Hurlstone A, Gärtner J. RNASET2-deficient cystic leukoencephalopathy: a new lysosomal disorder Neuropediatrics 2010. Conference paper