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Spatio-Temporal regulation of cytokinesis
Spatio-Temporal regulation of cytokinesis
Type 2 node proteins and NDR-family kinase localization
Type 2 node proteins and NDR-family kinase localization
We utilize quantitative confocal fluorescence microscopy to analyze the localization of the fission yeast NDR-family, Sid2p, and key regulatory components (classified as Type 2 interphase node proteins) throughout mitosis and cytokinesis to better understand how they work together to ensure timely and successful cell division.
Biophysical properties of fission yeast
Biophysical properties of fission yeast
Atomic Force Microscopy and cell wall biophysics
Atomic Force Microscopy and cell wall biophysics
Using atomic force microscopy, we characterize the biophysical properties of the fission yeast cell wall in response to changes in cellular morphology (such as in regions of polarized growth or division), genetic mutations (including a variety of cell signaling components), or environmental stimuli (such as osmotic stress).
Our work is funded through the Wellesley College small grants and an NSF MRI grant for 'Acquisition of an Integrated Atomic Force and Fluorescence Microscope to Enhance Undergraduate Research at Wellesley College'
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