Trajectories and segmentation of human bronchial epithelial cell

Cancerous human fibrosarcoma cells undergo collective migration at the edge of their colony by combining mesoscale self-organization and intrinsic handedness, showing how physical interactions alone can lead to biological functionality.

Evolution of human bronchial epithelial cell (HBEC) culture

 >>read more Phys. Rev. Lett. (2018) 120, 208101

Activity-driven collective flows of HBEC culture result in ensembles of vortices randomly positioned in space

>>read more Phys. Rev. Lett. (2018) 120, 208101

HBEC forming dynamic co-aligned domains. Nematic defects are found at the interface between domains. The total defect number remains unchanged as a result of dynamical balance of nucleation and annihilation events. 

>>read more Phys. Rev. Lett. (2018) 120, 208101

Transnational cryostage for directional freezing of cells adherent to a substrate 

Cryopreservation of adherent mammalian cells on a substrate.  

On substrate cryopreservation of three widely used epithelial cell lines: IEC-18, HeLa, and Caco-2 cells adhered to a substrate provides proof-of-concept for new freezing protocol that facilitates the growth of a vital confluent cell culture after thawing, dramatically shortening the post-thaw culturing time.

>>read more PLoS ONE (2018) 13(2): e0192265 

NCC-Foam (FP7 project)

Self-assembly of nano crystalline cellulose (NCC/CNC) for lightweight cellular structures. The controlled patterning of the micro-structure by directional freezing of CNC suspension. 

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