Publication

Journal articles:

(Note: # equal contribution / co-first author):

Manuscript in preparation:

1. Sajedeh Nasr Esfahani#, Yi Zheng#, Xufeng Xue, Agnes M. Resto-Irizarry, Yue Shao, and Jianping Fu. Reconstitution of human primordial germ cell development from pluripotent stem cells in a synthetic embryonic sac-like environment. Manuscript in preparation.

2. Shiying Liu#, Xufeng Xue#, Jianping Fu, and Cheri X. Deng. Acoustic tweezing cytometry for mechanobiology. Manuscript in preparation.

3.  Shiying Liu#, Xufeng Xue#, Jianping Fu, and Cheri X. Deng. Microbubble behaviors in acoustic tweezing cytometry regulates embryonic stem cell differentiation. Manuscript in preparation.

4. Xufeng Xue, Yue Liu, Jianping Fu. Developmental engineering of mammalian embryo models. Nature Reviews Bioengineering. Manuscript in preparation.

Submitted:

5. Xufeng Xue, Robin Zhexuan Yan, Yi Zheng, Yue Liu, Frederick C.F. Wong, Azim Surani, Orly Reiner, and Jianping Fu. A patterned human neural tube model using microfluidics. Nature, accepted.

6. Hayden Nunley, Xufeng Xue, Jianping Fu, and David K. Lubensky. Generation of fate patterns via intercellular forces. Physical Review Letters, Under revision.

7. Feng Lin, Xufeng Xue, Yi Zheng, Zida Li, Yue Shao, Chunyang Xiong, and Jianping Fu. Emergent primitive streak patterning from human pluripotent stem cells. Biomaterials, Under revision.

Published / Accepted:

8. Yi Zheng, Robin Zhexuan Yan, Mutsumi Kobayashi, Lifeng Xiang, Ran Yang, Alexander Goedel, Yu Kang, Xuefeng Xue, Sajedeh Nasr Esfahani, Yue Liu, Agnes M. Resto Irizarry, Weisheng Wu, Yunxiu Li, Weizhi Ji, Yuyu Niu, Kenneth R. Chien, Tianqing Li, Toshihiro Shioda, and Jianping Fu. Single-cell analysis of human embryoids reveals lineage diversification roadmaps of early development. Cell Stem Cell, Accepted, in press.

9. Zida Li, Feng Lin, Shue Wang, Xufeng Xue, and Yue Shao. Single-cell sequencing to unveil the mystery of embryonic development. Advanced Biology, 2101151, 2021.

10. Sajedeh Nasr Esfahani, Xufeng Xue, Agnes M. Resto Irizarry, Yue Shao, and Jianping Fu. Micro/nanoengineered technologies for human pluripotent stem cells maintenance and differentiation. Nano Today, vol. 41, 101310, 2021.

11.  Kejie Chen, Yi Zheng, Xufeng Xue, Yue Liu, Anges M. Resto-Irizarry, Huajing Tang, and Jianping Fu. Branching development of early post-implantation human embryonic-like tissues in 3d stem cell culture. Biomaterials, vol. 275, 120898, 2021.

12. Jonathon Muncie, Nadia Ayad, Johnathon Lakins, Xufeng Xue, Jianping Fu, Calerie Weaver. Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells. Developmental Cell, vol. 55, pp. 679-694, 2020.

13. Zhenzhen Fan, Xufeng Xue, Jianping Fu, and Cheri X. Deng. Visualization and quantification of dynamic intercellular coupling in human embryonic stem cells using single cell sonoporation. Scientific Reports, vol. 10, 18253, 2020.

14. Xufeng Xue, Ryan P. Wang, and Jianping Fu. Modeling of human neurulation using bioengineered pluripotent stem cell culture. Current Opinion in Biomedical Engineering, vol. 13, pp. 127-133, 2020.

15. Yuanyuan Zheng#, Xufeng Xue#, Agnes M. Resto-Irizarry, Zida Li, Yue Shao, Yi Zheng, Gang Zhao, and Jianping Fu. Dorsal-ventral patterned neural cyst from human pluripotent stem cells in a biomimetic neurogenic niche. Science Advances, vol. 5, eaax5933, 2019

16. Yi Zheng, Xufeng Xue, Yue Shao, Sicong Wang, Sajedeh Nasr Esfahani, Zida Li, Jonathon Muncie, Johnathon N. Lakins, Valerie M. Weaver, Deborah L. Gumucio, and Jianping Fu. Controlled modeling of human epiblast and amnion development using stem cells. Nature, vol. 573, pp. 421–425, 2019.

• Commentary by Amander T. Clark, Nature, vol. 573, pp. 350-351, 2019.

• Highlighted by Nature News, Nature Podcast, National Public Radio (NPR) News, BBC News, MIT Technology Review, and Chemical Engineering News (C&EN).

17. Sajedeh Nasr Esfahani#, Yue Shao#, Agnes M Resto-Irizarry, Zida Li, Xufeng Xue, Deborah L Gumucio, and Jianping Fu. Microengineered human amniotic ectoderm tissue array for high-content developmental phenotyping. Biomaterials, vol. 216, pp. 119244, 2019

18.  Feng Lin, Yue Shao, Xufeng Xue, Yi Zheng, Zida Li, Chunyang Xiong, Jianping Fu. Biophysical phenotypes and determinants of anterior vs. posterior primitive streak cells derived from human pluripotent stem cells. Acta Biomaterialia, vol. 86, pp. 125-134, 2018.

19. Zhenzhen Fan#, Xufeng Xue#, Reshani Perera, Sajedeh Nasr Esfahani, Agata A. Exner, Jianping Fu and Cheri X. Deng. Acoustic actuation of integrin-bound microbubbles for mechanical phenotyping during differentiation and morphogenesis of human embryonic stem cells. Small, vol. 14, 1803137, 2018.

20. Xufeng Xue#, Yubing Sun#, Agnes M. Resto-Irizarry, Ye Yuan, Koh Meng Aw Yong, Yi Zheng, Shinuo Weng, Yue Shao, Yimin Chai, Lorenz Studer, and Jianping Fu. Mechanics-guided embryonic patterning of neuroectoderm tissue from human pluripotent stem cells. Nature Materials, vol. 17, pp. 633-641, 2018.

• Commentary by Mukul Tewary and Peter W. Zandstra, Nature Materials, vol. 17, pp. 571-572, 2017.

• Highlighted by Michigan News, Michigan Engineering, UMass News, Phys.org, Futurity.

21. Tugba Topal#, Xiaowei Hong#, Xufeng Xue, Zhenzhen Fan, Ninad Kanetkar, Joe T. Nguyen, Jianping Fu, Cheri X. Deng, and Paul H. Krebsbach. Acoustic tweezing cytometry induces rapid initiation of human embryonic stem cell differentiation. Scientific Reports, vol. 8, 12977, 2018.

22. Yen P. Kong, Ana Y. Rioja, Xufeng Xue, Yubing Sun, Jianping Fu, and Andrew J. Putnam. A systems mechanobiology model to identify biomaterials that support cardiac reprogramming. Biomaterials, vol. 181, pp. 280-292, 2018.

23. Zida Li, Yize Wang, Xufeng Xue, Brendan McCraken, Kevin Ward, and Jianping Fu. Carbon Nanotube Strain Sensor Based Hemoretractometer for Blood Coagulation Testing. ACS Sensors, vol. 3, pp. 670–676, 2018

24. Zida Li, Xufeng Xue, Feng Lin, Yize Wang, Kevin Ward, and Jianping Fu. Capillary assisted deposition of carbon nanotube film for strain sensing. Applied Physics Letters, vol. 111, 173105, 2017.

25. Yue Shao#, Kenichiro Taniguchi#, Katherine Gurdziel, Ryan F. Townshend, Xufeng Xue, Koh Meng Aw Yong, Jianming Sang, Jason R. Spence, Deborah L. Gumucio, and Jianping Fu. Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche. Nature materials, vol. 16, pp. 419-425, 2017.

• Commentary by Martin Pera, Nature Materials, vol. 16, pp. 394-395, 2017.

26. Xufeng Xue, Xiaowei Hong, Zida Li, Cheri X. Deng, and Jianping Fu. Acoustic tweezing cytometry enhances osteogenesis of human mesenchymal stem cells through cytoskeletal contractility and YAP activation. Biomaterials, vol. 134, pp. 22-30, 2017.

27. Yi Zheng#, Shue Wang#, Xuefeng Xue, Alan Xu, Wei Liao, Alice Deng, Guohao Dai, Allen P. Liu, and Jianping Fu. Notch signaling in regulating angiogenesis in a 3D biomimetic environment. Lab on a Chip, vol. 17, pp. 1948-1959, 2017.

Book Chapter:

1. Yubing Sun, Yue Shao, Xufeng Xue, and Jianping Fu. Emerging Roles of YAP/TAZ in Mechanobiology. Molecular and Cellular Mechanobiology. (edited by Shu Chien, Adam J. Engler, and Yingxiao Wang) Springer, 2016.

Patent:

1. Xufeng Xue, Jianping Fu, Huajing Tang. Microfluidic devices and methods for development of neural tube-like tissues. U.S. Patent application, PCT/US2021/058090.