University of California, Riverside

Interdisciplinary Center for Quantitative Modeling in Biology

Journal Articles

·             Kevin Tsai, Zhen Zhou, Jiadong Yang, Zhiliang Xu, Shixin Xu, Roya Zandi, Nan Hao, Weitao Chen*, Mark Alber* (2024). Study of impacts of two types of cellular aging on the yeast bud morphogenesis. (* co-corresponding author) PLoS Comput Biol 20(9): e1012491. https://doi.org/10.1371/journal.pcbi.1012491.

·            Nilay Kumar#, Jennifer Rangel Ambriz#, Kevin Tsai#, Mayesha Sahir Mim, Weitao Chen, Jeremiah J. Zartman*, Mark Alber* (2024). Balancing competing effects of tissue growth and cytoskeletal regulation during Drosophila wing disc development. (#co-first author, *co-corresponding author) Nat Commun 15, 2477 (2024). 

·            Christian Michael, Mikahl Banwarth-Kuhn, Kevin Rodriguez, Calvin-Khang Ta, Amit Roy-Chowdhury, Weitao Chen*, Venugopala Reddy Gonehal*, Mark Alber* (2023). Role of Turgor-pressure Induced Boundary Tension in the Maintenance of the Shoot Apical Meristem of Arabidopsis Thaliana. (* co-corresponding author) J. R. Soc. Interface.202023017320230173.

·            Alireza Ramezani, Samuel Britton, Roya Zandi, Mark Alber, Ali Nematbakhsh*, Weitao Chen* (2023). A chemical-mechanical coupled model predicts roles of spatial distribution of morphogen in maintaining tissue growth. (* co-corresponding author)  npj Syst Biol Appl 9, 16 (2023).

·            Weitao Chen, Chiu-Yen Kao (2023). Review of Computational Approaches to Optimization Problems in Inhomogeneous Rods and Plates. Commun. Appl. Math. Comput. (2023). 

·            Kevin Rodrigueza, Albert Doa, Betul Senay-Arasa, Mariano Perales, Mark Alber, Weitao Chen*, G. Venugopala Reddy* (2022). Concentration-dependent transcriptional switching through a collective action of cis-elements. (a authors contributed equally to this work, * co-corresponding author) Sci Adv. 2022 Aug 12;8(32):eabo6157.

·             Kevin Rodriguez, Mikahl Banwarth-Kuhn, Christian Michael, Alexander Plong, Eric Bourgain-chang, Ali Nematbakhsh, Weitao Chen, Mark Alber, Venugopala Reddy Gonehal (2022). Combined computational modeling and experimental analysis integrating chemical and mechanical signals suggests possible mechanism of shoot meristem maintenance. PLOS Computational Biology 18.6 (2022): e1010199.

·             Alexander Plong, Kevin Rodriguez, Mark Alber, Weitao Chen*, G. Venugopala Reddy* (2021). CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient. (* co-corresponding author)  Nat Commun 12, 6361 (2021). 

·             Jolene Britton, Yat Tin Chow, Weitao Chen, Yulong Xing (2021). Recovery of a Time-Dependent Bottom Topography Function from the Shallow Water Equations via an Adjoint Approach. SIAM Journal on Scientific Computing, 43(4), pp.A2981-A3008.

·             Kevin Tsai, Samuel Britton, Ali Nematbakhsh, Roya Zandi, Weitao Chen*, Mark Alber* (2020). Role of combined cell membrane and wall mechanical properties regulated by polarity signals in cell budding. (* co-corresponding author) Physical Biology 17 065011.

·             Ali Nematbakhsh, Megan Levis, Weitao Chen, Jeremiah Zartman, Mark Alber (2020). Epithelial organ shape is generated by patterned actomyosin contractility and maintained by the extracellular matrix. PLoS Comput Biol 16(8): e1008105.

·            Xue Pan, Linjing Fang, Jianfeng Liu, Betul Senay-Aras, Wenwei Lin, Shuan Zheng, Tong Zhang, Jingzhe Guo, Uri Manor, Jaimie Van Norman, Weitao Chen*, Zhenbiao Yang* (2020). Auxin-induced signaling protein nanoclustering contributes to cell polarity formation. (* co-corresponding author) Nature Communications, 11(1), pp.1-14. 

·             Yilun Zhu, Yuchi Qiu, Weitao Chen, Qing Nie, Arthur Lander. Scaling a Dpp morphogen gradient through feedback control of receptors and co-receptors. Developmental Cell, 53, no.6 (2020), pp.724-739. 

·             Yangyang Wang, Christian F. Guerrero-Juarez, Yuchi Qiu, Huijing Du, Weitao Chen, Seth Figueroa, Maksim V. Plikus, Qing Nie (2019). A Multiscale Hybrid Mathematical Model of Epidermal-dermal Interactions during Skin Wound Healing. Experimental dermatology 28.4 (2019): 493-502.

·             Yuchi Qiu, Weitao Chen, Qing Nie. A Hybrid Method for Stiff Reaction-Diffusion Equations. Discrete & Continuous Dynamical Systems-B 24.12 (2019): 6387.

·            Yuchi Qiu, Weitao Chen, Qing Nie. Stochastic dynamics of cell lineage in tissue homeostasis. Discrete & Continuous Dynamical Systems-B (2019): 853-865.

·             Weitao Chen, Qing Nie, Tau-Mu Yi, Ching-Shan Chou. Modelling of Yeast Mating Reveals Robustness Strategies for Cell-Cell Interactions, PLoS Computational Biology, 12(7):e1004988, 2016.

·             Weitao Chen, Ching-Shan Chou, Chiu-Yen Kao. Minimizing Eigenvalues for Inhomogeneous Rods and Plates, Journal of Scientific Computing, 0885-7474, pp. 1-31, 2016.

·             *Dongyong Wang, *Weitao Chen, Qing Nie. Semi-implicit Integration Factor Methods on Sparse Grids for High-Dimensional Systems, Journal of Computational Physics, 292, 43-55,2015 (*equal contribution).

·             Weitao Chen, Ching-Shan Chou, Chiu-Yen Kao. Lax-Friedrichs Multigrid Fast Sweeping Methods for Steady State Problems for Hyperbolic Conservation Laws, Journal of Scientific Computing, 0885-7474, pp. 1-28, 2015.

·             Weitao Chen, Ching-Shan Chou, Chiu-Yen Kao. Conservative Fast Sweeping Methods for Steady State Problems for Hyperbolic Conservation Laws, Journal of Computational Physics, 234, pp. 452-471, 2012. 

Book Chapter

·             Weitao Chen, Kenneth Diest, Chiu Yen Kao, Daniel E. Marthaler, Luke A. Sweatlock, and Stanley Osher. Numerical Methods for Metamaterial Design, Chapter 7 on Gradient Based Optimization Methods for Metamaterial Design, Pages 175-204, Topics in Applied Physics, 127, Springer, 2013.

·             Velagala, Vijay, Weitao Chen, Mark Alber, and Jeremiah J. Zartman. "Multiscale Models Coupling Chemical Signaling and Mechanical Properties for Studying Tissue Growth." In Mechanobiology, pp. 173-195. Elsevier, 2020.

Thesis

·             Weitao Chen. Fast sweeping methods for steady state hyperbolic conservation problems and numerical applications for shape optimization and computational cell biology. Ph.D. thesis, The Ohio State University, 2013.