See images below for a brief tutorial on use of this tool.
Go to the link above and choose the value you wish to calculate (PPV or NPV).
Select the chromosome condition you would like to calculate and maternal age at EDD for the patient from the drop lists.
After selecting the chromosome/age, you must run the calculator by selecting the "Calculate" button. Prior to this, you will see the sensitivity/specificity of the test for the chromosome/age combination you have proposed; however, this is NOT the final result of the calculation.
After running the calculator, the final results (positive/negative predictive value) and false positive/negative rate will be shown. This is the final result of the calculator.