Translational Neurophysiology Laboratory

Neuromodulation   Neurocardiology   Neuroimmunology

At the TNP lab, we study the communication between the cardiovascular, immune and nervous systems and leverage the knowledge we gain to treat human disease. We use methods from neuroscience, neural engineering, immunology and cardiovascular medicine to study neuroimmune mechanisms of disease, test neuromodulation interventions and develop treatments for patients with cardiovascular diseases. In parallel, we train scientists and physician-scientists in the emerging field of bioelectronic medicine. 

Here you can find the latest news from our group, an overview of our research, our publications, information on lab members, and open lab positions.

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We are a team of physicians, physician-scientists, scientists and engineers, working in: 

• Neural regulation of immunity and homeostasis

We study the neural circuits, physiological mechanisms and neuroimmune pathways by which the nervous system senses and regulates immune and metabolic processes and cardiopulmonary functions.

• Precision autonomic neuromodulation

We develop methods to deliver more organ- and function-selective devices that target mechanisms specific to the affected organ(s), often delivered in closed-loop mode.

• Neuroimmune dysfunction and modulation in cardiovascular diseases

We study how neuroimmune dysfunction contributes to the pathogenesis cardiovascular diseases with an inflammatory component, such as pulmonary hypertension, heart failure and cardiac arrhythmias. We also test neuroimmune modulation therapies for the same diseases. 

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