Genomics, Epigenomics and Transcriptomics
In the realm of genomics, my focus lies in leveraging advanced computational techniques to analyze large-scale genomic datasets. By identifying somatic mutations, copy number variations, and structural alterations, I aim to elucidate the genomic landscape of cancer and pinpoint key driver events that contribute to tumorigenesis. This exploration not only enhances our understanding of the genetic basis of cancer but also holds the potential to unveil novel therapeutic targets.
Transcriptomics constitutes another cornerstone of my research, where I employ sophisticated algorithms to analyze gene expression patterns across diverse cancer types. Unravelling the intricate network of dysregulated genes provides valuable insights into the molecular signatures associated with different cancer subtypes and aids in the identification of prognostic markers and therapeutic vulnerabilities.
Additionally, I delve into the epigenetic landscape of cancer through the analysis of methylation data. By deciphering aberrant DNA methylation patterns, I strive to uncover epigenetic modifications that drive oncogenic processes and influence the tumor microenvironment.
Multi-omics Data integration
Recognizing the complex interplay of diverse molecular layers, I am committed to developing innovative strategies that harmonize and analyze multi-dimensional omics datasets cohesively. The amalgamation of genomics, transcriptomics, and methylation data provides a holistic view of the molecular landscape in cancer.
Through the lens of multi-omics integration, my research endeavors strive to identify key molecular signatures, biomarkers, and potential therapeutic targets that may remain elusive when analyzed separately. This approach allows for a more nuanced understanding of the molecular heterogeneity inherent in cancer, paving the way for personalized and targeted treatment strategies.
Software/Algorithm development
Beyond data integration, my focus extends to the forefront of algorithmic innovation. I aspire to unveil latent patterns concealed within omics datasets. In essence, the marriage of advanced algorithms with integrated omics data serves as a powerful tool for extracting meaningful insights that can inform more precise and personalized approaches to cancer research and treatment.