Journal club

12Feb24

Massively parallel measurement of protein–protein interactions by sequencing using MP3-seq

De novo designed proteins neutralize lethal snake venom toxins

Single-Molecule Investigation of the Protein–Aptamer Interactions and Sensing Application Inside the Single Glass Nanopore


15Jan25

Supervised multi-frame dual-channel denoising enables long-term single-molecule FRET under extremely low photon budget


06Jan25

Tracking transcription–translation coupling in real time


18Dec24

Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH


10Dec24

Spatially resolved, highly multiplexed RNA profiling in single cells


04Dec24

Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells


27Nov24

Single-molecule fluorescence multiplexing by muti-parameter spectroscopic detection of nanostructured FRET labels


20Nov24

ABEL-FRET: tether-free single-molecule FRET with hydrodynamic profiling


13Nov24

Spatially resolved, highly multiplexed RNA profiling in single cells 


06Nov24

Quantifying T cell receptor mechanics at membrane junctions using DNA origami tension sensors


30Oct24

RNA-guided RNA silencing by an Asgard archaeal Argonaute


23Oct24

Mechanical force regulates ligand binding and function of PD-1


16Oct24

Multi-pass, single-molecule nanopore reading of long protein strands.


02Oct24

A single-vesicle content mixing assay for SNARE-mediated membrane fusion.


25Sep24

Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes. 


13Sep24

Exploring molecular biology in sequence space: The road to next-generation single-molecule biophysics


04Sep24

A single-vesicle content mixing assay for SNARE-mediated membrane fusion


28Aug24

Distance Dependence of Single-Fluorophore Quenching by Gold Nanoparticles Studied on DNA Origami


21Aug24

TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity. 


14Aug24

Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning. 


07Aug24

Single-molecule FRET imaging of GPCR dimers in living cells. 


31JUL24

DropBlot: single-cell western blotting of chemically fixed cancer cells.


17JUL24

Torsional Stiffness of Extended and Plectonemic DNA 


10JUL24

Biological Nanopore Approach for Single-Molecule Protein Sequencing 


03JUL24

Single-Molecule Peptide Identification Using Fluorescence Blinking Fingerprints

 

26JUN24

A DNA origami-based device for investigating DNA bending proteins by transmission electron microscopy 

 

19JUN24

A Systems Approach to Measuring the Binding Energy Landscapes of Transcription Factors

 

12JUN24

Affinity microfluidics enables high-throughput protein degradation analysis in cell-free extracts 

 

17APR24

Mapping Single-Molecule Protein Complexes in 3D with DNA Nanoswitch Calipers

 

11APR24

Supported Bilayer Electrophoresis under Controlled Buffer Conditions 

 

03APR24

An electroactive microwell array device to realize simultaneous trapping of single cancer cells and clusters

 

28MAR24

An electroactive microwell array device to realize simultaneous trapping of single cancer cells and clusters

 

20MAR24

ProtSeq: Toward high-throughput, single-molecule protein sequencing via amino acid conversion into DNA barcodes

 

13MAR24

Protein Separation by Electrophoretic–Electroosmotic Focusing on Supported Lipid Bilayers

 

06MAR24

Enzyme-less nanopore detection of post-translational modifications within long polypeptides

 

27FEB24

Single molecule electrometry

 

22FEB24

Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device

 

07FEB24

Single molecule digital sizing:

 

24JAN24

Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity:

 

03JAN24

Real-Time Structural Biology of DNA and DNA-Protein Complexes on an Optical Microscope

 

27DEC23

Single Protein molecules separation, tracking and counting in ultra-thin silicon channels

 

20DEC23

Optical imaging of single-protein size, charge, mobility, and binding