Shoichi Tachiyama
Dr. Tachiyama earned his Ph.D. in Biochemistry and Biophysics at the University of Kansas in 2020. In his Ph.D. projects, he used biochemical and microbiological approaches to research molecular functions and protein interactions on the cytoplasmic components of the Shigella type III secretion system (T3SS). In 2020, he joined Dr. Jun Liu’s laboratory at Yale School of Medicine and has continued to research the Shigella T3SS in situ. This research project is conducted in collaboration with Dr. William Picking, University of Missouri. Dr. Tachiyama’s work also focuses on structural details of the flagellar motor in Helicobacter pylori and Campylobacter jejuni using in-situ approaches.
He is now an Specially Appointed Associate Professor at the University of Osaka. In his laboratory, advanced cryo-EM approaches, such as cryo-focused ion beam (cryo-FIB) milling and cryo-ET, are applied to capture host-pathogen interactions sites in situ to investigate how pathogens invade into host cells.