Most recent publications:
Gilger BC, Song L, Hasegawa T, Salmon JH, Bower JJ, Vridhachalam N, Collins E, Roberts D, Bagel J, Molony C, Vite C, Hirsch ML. Adeno-associated vector corneal gene therapy reverses corneal clouding in a feline model of mucopolysaccharidosis VI. PLoS One. 2025
Suarez-Amaran L# Song L# Tretiakova A#, Mikhail S, Samulski RJ, AAV vector development, back to the future, Molecular Therapy. 2025. (Journal cover)
Song L, Brown N, Bower JJ, Tomoko H, Samulski RJ, Hirsch ML. AAV Vector Transduction Restriction and Attenuated Toxicity in hESCs via a Rationally Designed Inverted Terminal Repeat. Nucleic Acids Research. 2025
Nilles J, Roberts D, Salmon J, Song L, O'Dea C, Marjoram L, Bower JJ, Hirsch M, Gilger B. AAV-mediated expression of HLA-G for the prevention of experimental ocular graft host disease. Mol Ther Methods Clin Dev. 2023
Umaña JD, Wasserman SR, Song L, Goel AA, Yu X, Jin J, Hathaway Chemical Epigenetic Regulation of Adeno-Associated Virus Delivered Transgenes. Hum Gene Ther. 2023
Bower JJ, Z Song, Song L*. Subconjunctival administration of Adeno-associated Virus (AAV) vectors in small animal models, JoVE, 2022
Crabtree E, Uribe K, Smith SM, Roberts D, Salmon JH, Bower JJ, Song L, Bastola P, Hirsch ML, Gilger Inhibition of experimental autoimmune uveitis by intravitreal AAV-Equine-IL10 gene therapy. PLoS One. 2022
Song ZW, Shao WW, Song L, Pei XL, Li CW, Human hepatocyte transduction with adeno-associated virus vector, Methods in Molecular Biology, 2022
Dong L, Li N, Wei X, Wang Y, Chang L, Wu H, Song L, Guo K, Shen Y, Wang F. A gambogic acid-loaded delivery system mediated by ultrasound-targeted microbubble destruction: A promising therapy method for malignant cerebral glioma, Int J Nanomedicine, 2022
Bower JJ, Song L, Bastola P, Hirsch ML, Harnessing the natural biology of Adeno-Associated Virus to enhance the efficacy of cancer gene therapy. Viruses. 2021.
Song L, Samulski RJ, Hirsch AAV vector mobilization, risk vs reality. PMID: 32829671, Human Gene Therapy. 2020. (Journal cover article)
Song L, Bower JJ, Llanga T, Salmon JH, Hirsch ML, Gilger Ocular tolerability and immune response to corneal intrastromal AAV-IDUA gene therapy in New Zealand White rabbits. PMID: 32542182, Molecular Therapy-Methods & Clinical Development, 2020.
Bastola P, Song L, Gilger BC, Hirsch ML, Adeno-associated virus mediated gene therapy for corneal Special issue on Ocular Drug Delivery: Present Innovations and Future Challenges. PMID: 32823625, Pharmaceutics, 2020.
Miyadera K, Conatser L, Llanga T, Carlin K, O’Donnell P, Bagel J, Song L, Kurtzberg J, Samulski RJ, Gilger BC & Hirsch Intrastromal AAV gene therapy prevents and reverses advanced corneal clouding in a canine model of mucopolysaccharidosis I. PMID: 32330426, Molecular Therapy, 2020. (Journal cover article)
Song L, Hirsch ML. Dramatically distinct tropism and transduction efficiencies of AAV serotypes following subconjunctival Atlas of Science. https://atlasofscience.org/dramatically-distinct-tropism-and-transduction-efficiencies-of-aav-serotypes-following-subconjunctival-injection/ January 23, 2020.