DINE COMMAND-LIKE NEURON

DINE is a non-superficial neuron located in the buccal ganglia between the landmark neurons B2 and B3. It has a single projection down the ipsilateral cerebral buccal connective. Artificial activation of a single DINE is sufficient to drive fictive feeding cycles which last for the duration that DINE is activated. DINE has an excitatory connection with feeding neurons located in the cerebral ganglia, including command-like interneurons CV1a and CV1b, modulatory interneuron CGC and motoneuron CV3. DINE has no known outputs onto buccal neurons but is strongly activated by the buccal command-like interneuron vTN. DINE drives ingestion fictive feeding cycles.

References

Crossley, M., Simon, A., Marathe, S., Rau, C., Roth, A., Marra, V., Staras, K., 2025. Functional mapping of the molluscan brain guided by synchrotron X-ray tomography. PNAS.