Huang CY, Helen N, J. LD, and Lai JJ. Rapid isolation of extracellular vesicles from stem cell conditioned medium using osmosis-driven filtration. Science and Technology of Advanced Materials. 2025;26(1):2485668.
Gilligan-Steinberg SD, Kline EC, Wang Q, Britton RJ, Kim W, Rupp JW, Gu H, Beck IA, Hull IT, Panpradist N, Stekler JD, Frenkel LM, Drain PK, Lai JJ, Lutz BR. Development of a Highly Multiplexed RT-LAMP Assay for Coverage of Genetic Sequence Diversity. Anal Chem. 2025;97(7):4005-13. Epub 20250213.
Wang Q, Kline EC, Gilligan-Steinberg SD, Lai JJ, Hull IT, Olanrewaju AO, Panpradist N, Lutz BR. Sensitive Pathogen Detection and Drug Resistance Characterization Using Pathogen-Derived Enzyme Activity Amplified by LAMP or CRISPR-Cas. medRxiv. 2024. Epub 20240401.
Wang Q, Gilligan-Steinberg SD, Kim W, Kline EC, Hull IT, Lai JJ, Lutz BR. Large-volume RT-LAMP enables extraction-free amplification of HIV RNA from fingerstick plasma. Anal Chim Acta. 2024 Jun 8;1307:342560.
Lai JJ, Hill JJ, Huang CY, Lee GC, Mai KW, Shen MY, Wang SK. Unveiling the Complex World of Extracellular Vesicles: Novel Characterization Techniques and Manufacturing Considerations. Chonnam Med J. 2024 Jan;60(1):1-12. doi: 10.4068/cmj.2024.60.1.1.
Wang Q, Panpradist N, Kotnik JH, Willson RC, Kourentzi K, Chau ZL, Liu JK, Lutz BR, Lai JJ. A simple agglutination system for rapid antigen detection from large sample volumes with enhanced sensitivity. Analytica Chimica Acta. 2023;1277:341674.
Jaimes M, Liao C, Chen M, Czosseck A, Lee T, Chou Y, Chen Y, Lin S, Lai J, Lundy D. Assessment of circulating extracellular vesicles from calorie-restricted mice and humans in ischaemic injury models. Journal of Extracellular Biology. 2023/05; 2(5):e86.
Gulati GK, Panpradist N, Stewart SWA, Beck IA, Boyce C, Oreskovic AK, García-Morales C, Avila-Ríos S, Han PD, Reyes-Terán G, Starita LM, Frenkel LM, Lutz B, Lai JJ. Simultaneous monitoring of HIV viral load and screening of SARS- CoV-2 employing a low-cost RT-qPCR test workflow. Analyst. 2022. doi: 10.1039/D2AN00405D.
Chen S-Y, Wu AY, Lunde R, Lai JJ. Osmotic Processor for Enabling Sensitive and Rapid Biomarker Detection via Lateral Flow Assays. Frontiers in Bioengineering and Biotechnology. 2022;10.
Lai JJ, Chau ZL, Chen S-Y, Hill JJ, Korpany KV, Liang N-W, Lin L-H, Lin Y-H, Liu JK, Liu Y-C, Lunde R, Shen W-T. Exosome Processing and Characterization Approaches for Research and Technology Development. Advanced Science. 2022;9(15):2103222 .
Hull IT, Kline EC, Gulati GK, Kotnik JH, Panpradist N, Shah KG, Wang Q, Frenkel L, Lai J, Stekler J, Lutz BR . Isothermal Amplification with a Target-Mimicking Internal Control and Quantitative Lateral Flow Readout for Rapid HIV Viral Load Testing in Low-Resource Settings. 2022;94(2):1011-21.
Huang S-S, Lee K-J, Chen H-C, Prajnamitra Ray P, Hsu C-H, Jian C-B, Yu X-E, Chueh D-Y, Kuo Chiung W, Chiang T-C, Choong Oi K, Huang S-C, Beh Chaw Y, Chen L-L, Lai James J, Chen P, Kamp Timothy J, Tien Y-W, Lee H-M, Hsieh Patrick C-H. Immune cell shuttle for precise delivery of nanotherapeutics for heart disease and cancer. Sci Adv. 2021;7(17):eabf2400.
Hironaka K, Yoshihara E, Nabil A, Lai JJ, Kikuchi A, Ebara M. Conjugation of antibody with temperature-responsive polymer via in situ click reaction to enable biomarker enrichment for increased diagnostic sensitivity. Biomaterials Science. 2021;9(14):4870-9.
Chen P-C, Lai JJ, Huang C-J. Bio-Inspired Amphoteric Polymer for Triggered-Release Drug Delivery on Breast Cancer Cells Based on Metal Coordination. ACS Appl Mater Interfaces. 2021;13(22):25663-73.
Hoffman AS, Lai JJ. Three significant highlights of controlled drug delivery over the past 55 years: PEGylation, ADCs, and EPR. Advanced Drug Delivery Reviews. 2020;158:2-3.
Panpradist N, Beck IA, Vrana J, Higa N, McIntyre D, Ruth PS, So I, Kline EC, Kanthula R, Wong-On-Wing A. OLA-Simple: A software-guided HIV-1 drug resistance test for low-resource laboratories. EBioMedicine. 2019;50:34-44.
Oreskovic A, Brault ND, Panpradist N, Lai JJ, Lutz BR. Analytical Comparison of Methods for Extraction of Short Cell-Free DNA from Urine. The Journal of Molecular Diagnostics. 2019;21(6):1067-78.
Fu Z, Lu Y-C, Lai JJ. Recent advances in biosensors for nucleic acid and exosome detection. Chonnam medical journal. 2019;55(2):86-98.
Jauregui R, Srinivasan S, Vojtech LN, Gammill HS, Chiu DT, Hladik F, Stayton PS, Lai JJ. Temperature-Responsive Magnetic Nanoparticles for Enabling Affinity Separation of Extracellular Vesicles. ACS Appl Mater Interfaces. 2018;10(40):33847-56.
Duarte HA, Panpradist N, Beck IA, Lutz B, Lai J, Kanthula RM, Kantor R, Tripathi A, Saravanan S, MacLeod IJ. Current status of point-of-care testing for human immunodeficiency virus drug resistance. The Journal of infectious diseases. 2017;216(suppl_9):S824-S8.
Wu JP, Cheng B, Roffler SR, Lundy DJ, Yen CY, Chen P, Lai JJ, Pun SH, Stayton PS, Hsieh PC. Reloadable multidrug capturing delivery system for targeted ischemic disease treatment. Science Translational Medicine. 2016;8(365):365ra160-365ra160.
Phan JC, Nehilla BJ, Srinivasan S, Coombs RW, Woodrow KA, Lai JJ. Human Immunodeficiency Virus (HIV) Separation and Enrichment via the Combination of Antiviral Lectin Recognition and a Thermoresponsive Reagent System. Pharm Res. 2016;33(10):2411-20.
Nehilla BJ, Hill JJ, Srinivasan S, Chen Y-C, Schulte TH, Stayton PS, Lai JJ. A Stimuli-Responsive, Binary Reagent System for Rapid Isolation of Protein Biomarkers. Analytical Chemistry. 2016;88(21):10404-10.
Graham DJ, Wilson JT, Lai JJ, Stayton PS, Castner DG. Three-dimensional localization of polymer nanoparticles in cells using ToF-SIMS. Biointerphases. 2016;11(2):02A304.
Lai JJ, Stayton PS. Improving Lateral-Flow Immunoassay (LFIA) Diagnostics via Biomarker Enrichment for mHealth. Mobile Health Technologies: Methods and Protocols. 2015:71-84.
Chen K-H, Lundy DJ, Toh E-W, Chen C-H, Shih C, Chen P, Chang H-C, Lai JJ, Stayton P, Hoffman A. Nanoparticle distribution during systemic inflammation is size-dependent and organ-specific. Nanoscale. 2015;7(38):15863-72.
Omura T, Ebara M, Lai JJ, Yin X, Hoffman AS, Stayton PS. Design of Smart Nanogels that Respond to Physiologically Relevant pH Values and Temperatures. Journal of nanoscience and nanotechnology. 2014;14(3):2557-62.
Hoffman JM, Stayton PS, Hoffman AS, Lai JJ. A Stimuli-Responsive Reagent System for Enabling Microfluidic Immunoassays with Biomarker Purification and Enrichment. Bioconjugate chemistry. 2015;26(1):29-38.
Roy D, Nehilla BJ, Lai JJ, Stayton PS. Stimuli-Responsive Polymer-Antibody Conjugates via RAFT and Tetrafluorophenyl Active Ester Chemistry. ACS Macro Letters. 2013;2(2):132-6.
Ebara M, Hoffman JM, Hoffman AS, Stayton PS, Lai JJ. A Photoinduced Nanoparticle Separation in Microchannels via pH-Sensitive Surface Traps. Langmuir. 2013;29(18):5388-93.
Chang M-Y, Yang Y-J, Chang C-H, Tang AC, Liao W-Y, Cheng F-Y, Yeh C-S, Lai JJ, Stayton PS, Hsieh PC. Functionalized nanoparticles provide early cardioprotection after acute myocardial infarction. Journal of Controlled Release. 2013;170(2):287-94.
Hoffman JM, Ebara M, Lai JJ, Hoffman AS, Folch A, Stayton PS. A helical flow, circular microreactor for separating and enriching “smart” polymer–antibody capture reagents. Lab on a Chip. 2010;10(22):3130-8.
Golden AL, Battrell CF, Pennell S, Hoffman AS, J. Lai J, Stayton PS. Simple fluidic system for purifying and concentrating diagnostic biomarkers using stimuli-responsive antibody conjugates and membranes. Bioconjugate chemistry. 2010;21(10):1820-6.
Nash MA, Lai JJ, Hoffman AS, Yager P, Stayton PS. “Smart” diblock copolymers as templates for magnetic-core gold-shell nanoparticle synthesis. Nano letters. 2009;10(1):85-91.
Lai JJ, Nelson KE, Nash MA, Hoffman AS, Yager P, Stayton PS. Dynamic bioprocessing and microfluidic transport control with smart magnetic nanoparticles in laminar-flow devices. Lab on a Chip. 2009;9(14):1997-2002.
Lai JJ, Hoffman JM, Ebara M, Hoffman AS, Estournès C, Wattiaux A, Stayton PS. Dual magnetic-/temperature-responsive nanoparticles for microfluidic separations and assays. Langmuir. 2007;23(13):7385-91.
Lai J-i, Shafi KV, Ulman A, Loos K, Lee Y, Vogt T, Lee W-L, Ong N. Controlling the size of magnetic nanoparticles using pluronic block copolymer surfactants. J Phys Chem B. 2005;109(1):15-8.
Lai J, Shafi KV, Ulman A, Loos K, Popovitz-Biro R, Lee Y, Vogt T, Estournès C. One-step synthesis of core (Cr)/shell (γ-Fe2O3) nanoparticles. Journal of the American Chemical Society. 2005;127(16):5730-1.
Lai J, Shafi KV, Ulman A, Loos K, Yang N-L, Cui M-H, Vogt T, Estournès C, Locke DC. Mixed iron-manganese oxide nanoparticles. J Phys Chem B. 2004;108(39):14876-83.
Kudasheva DS, Lai J, Ulman A, Cowman MK. Structure of carbohydrate-bound polynuclear iron oxyhydroxide nanoparticles in parenteral formulations. Journal of inorganic biochemistry. 2004;98(11):1757-69.
Shafi KV, Ulman A, Lai J, Yang N-L, Cui M-H. A new route to alumoxane gel: a versatile precursor to γ-alumina and alumina-based ceramic oxides. Journal of the American Chemical Society. 2003;125(14):4010-1.
Lai J, Shafi KV, Loos K, Ulman A, Lee Y, Vogt T, Estournès C. Doping γ-Fe2O3 Nanoparticles with Mn (III) Suppresses the Transition to the α-Fe2O3 Structure. Journal of the American Chemical Society. 2003;125(38):11470-1.
Uthaman S, Park I-K, Huh KM, Lai J, Ebara M. Editorial: Stimuli-Responsive Nanoparticles for Anti-cancer Therapy. Frontiers in Bioengineering and Biotechnology. 2021;9:1080.
Chen H-Y*, Hayashi T*, Koenig M*, Lai JJ*. Editorial: Polymer Surface Chemistry: Biomolecular Engineering and Biointerfaces. Frontiers in Chemistry. 2019;7:271.
Liu AY*, Crnogorac-Jurcevic T, Lai JJ, Lam HM. Antibody therapy targeting cancer-specific cell surface antigen AGR2. In: Arnouk H, editor. Cancer Targeted Immunotherapy in the Era of Precision Medicine: IntechOpen; 2021. DOI: 10.5772/intechopen.96492
Panpradist N, Lai JJ*. 4.1 - Point-of-Care Diagnostics. In: Ebara M, editor. Biomaterials Nanoarchitectonics: William Andrew Publishing; 2016. p. 139-56.
Lai JJ, Convertine A, Stayton PS*. Stimuli-Responsive Bioconjugate. In: Kobayashi S, K Ml, editors. Encyclopedia of Polymeric Nanomaterials: Springer Berlin Heidelberg; 2015. p. 1-13.
Nash MA, Golden AL, Hoffman JM, Lai JJ, Stayton PS*. Smart Surfaces for Point-of-Care Diagnostics. Intelligent Surfaces in Biotechnology. 2012:31-70. doi:10.1002/9781118181249.ch2