ROS Modulation & Nanozyme-Based Therapeutic SystemsÂ
ROS Modulation & Nanozyme-Based Therapeutic SystemsÂ
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In this research area, we focus on the development of nanozyme-based therapeutic systems that enable precise and bidirectional modulation of ROS, allowing controlled regulation of cellular fate and tissue responses.
In this research area, we focus on the development of nanozyme-based therapeutic systems that enable precise and bidirectional modulation of ROS, allowing controlled regulation of cellular fate and tissue responses.
By engineering functional nanozymes and redox-responsive nanomaterials, we design platforms capable of both ROS scavenging and ROS generation, enabling fine control over redox signaling pathways involved in inflammation, angiogenesis, immune activation, and non-apoptotic cell death mechanisms.
By engineering functional nanozymes and redox-responsive nanomaterials, we design platforms capable of both ROS scavenging and ROS generation, enabling fine control over redox signaling pathways involved in inflammation, angiogenesis, immune activation, and non-apoptotic cell death mechanisms.
One crucial component of the research is the development of nanocarrier systems for poorly soluble photosensitizers, which enable efficient delivery, stabilization, and controlled activation of photodynamic agents. Through these systems, we integrate photodynamic therapy (PDT) as a spatiotemporally controllable approach for localized ROS generation, allowing selective therapeutic action while minimizing off-target damage.
One crucial component of the research is the development of nanocarrier systems for poorly soluble photosensitizers, which enable efficient delivery, stabilization, and controlled activation of photodynamic agents. Through these systems, we integrate photodynamic therapy (PDT) as a spatiotemporally controllable approach for localized ROS generation, allowing selective therapeutic action while minimizing off-target damage.
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