Pharmaceutical Formulation & Stabilization
In this research area, we focus on pharmaceutical formulation and stabilization strategies for advanced therapeutics with particular emphasis on lyophilized injectable formulations and oral dosage forms.
We systematically investigate how formulation components, excipients, and processing conditions influence the conformational stability, aggregation behavior, and reconstitution performance of proteins, peptides, RNA therapeutics, and nanomaterial-based systems.
Our work on lyophilized formulations addresses critical challenges, including long-term stability, cold-chain independence, and usability in resource-limited or extreme environments. By utilizing nanostructured carriers/protective formulations, and optimizing freeze–drying cycles, cryo-/lyoprotectant systems, and reconstitution kinetics, we design stable injectable formulations suitable for both terrestrial healthcare and space medicine applications.