Priya Rajasethupathy

The Rajasethupathy Lab is interested in understanding memory processing in the mammalian brain during health and disease. We hope to reveal genetic and circuit-level mechanisms that enable the distributed nature of memory representations as they form, stabilize, and reorganize over time. Of particular interest are the mechanisms the brain uses for top-down control of goal-directed memory processing, where prior knowledge is used to guide future learning, in a way that can enable (or impede) cognitive flexibility. The lab uses genomic analyses, neural imaging coupled with real-time manipulations of brain activity, and virtual-reality based rodent behavioral paradigms to explore these questions.