Neurobiology Group
Dr. Subashchandrabose Chinnathambi Lab
“The brain is a world consisting of a number of unexplored continents and great stretches of unknown territory.”
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Group Members
Group Members
Dr. Subashchandrabose Chinnathambi (Subash)
Dr. Subashchandrabose Chinnathambi (Subash)
Subashchandrabose Chinnathambi, Ph.D.,
Subashchandrabose Chinnathambi, Ph.D.,
Additional Professor
Additional Professor
Department of Neurochemistry
Department of Neurochemistry
National Institute of Mental Health and Neuro Sciences
National Institute of Mental Health and Neuro Sciences
(NIMHANS),
(NIMHANS),
Institute of National Importance
Institute of National Importance
Bangalore – 560029, Karnataka, India.
Bangalore – 560029, Karnataka, India.
Phone no: 080-26995163
Phone no: 080-26995163
E-mail: bosesd@gmail.com
E-mail: bosesd@gmail.com
&
&
Former Associate Professor/Principal Scientist
Former Associate Professor/Principal Scientist
Biochemical Sciences Division
Biochemical Sciences Division
CSIR-National Chemical Laboratory
CSIR-National Chemical Laboratory
Pune.
Pune.
Ph.D. Students
Hariharakrishnan Chidambaram
Hariharakrishnan Chidambaram
Mr. Hariharakrishnan Chidambaram, (Hari) Ph.D., Student (DBT-JRF)
B. Tech. Biotechnology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu.
Email: ch.krishna@ncl.res.in
In Alzheimer’s disease, G-Protein Coupled Receptors (GPCRs) are involved in phosphorylation of Tau through various down-stream kinases such as GSK-3β and ERKs. We are interested to know the signalling cascades involved in Tau phosphorylation. We are keen to know the direct interaction of Tau with microglial GPCRs such as purinergic P2Y12 receptor and chemokine CX3CR1 receptors that help these phagocytic cells in Tau clearance in AD brain. In addition, we study several mechanisms of Tau intake by microglia such as endocytosis and LC-3 associated phagocytosis.
My other interests include gymming, adventure travels and sight seeing.
Mrs. Smita Eknath Desale, (Smita) Ph.D., Student (DBT-JRF)
M. Sc.Biotechnology, Mumbai University Mumbai.
Email: se.desale@ncl.res.in
Dietary fatty acids have major influence on brain specially omega-3 fatty acids. They have ability to change the functionalities of brain cells majorly microglia cells. In this study we try to check the effect of omega -3 fatty acids on microglial phenotype. The fatty acids would convert microglia cells towards M2 phagocytic microglia, in this study we would like to check the markers , expression profile of M2 microglia and its role in reducing Tau propagation in Alzheimer’s disease.
Other than science my interests are travelling, trekking, reading.
Smita Desale
Smita Desale
Tazeen Qureshi
Ms. Tazeen Qureshi (Tazeen), Ph.D. student (DST-INSPIRE), August 2020
M.Sc. Biophysics, Mumbai University, Mumbai.
Email: t.qureshi@ncl.res.in
Histone Deacetylase 6 is a unique HDAC in that it performs numerous cytoplasmic functions. It interacts with many different molecules in the cell and its entire potential hasn't been fully tapped into. From the preliminary studies in the lab, HDAC6 has been observed to modulate the aggregation properties of Tau protein. Our interest lies in understanding the mechanism of these modulation effects in-vitro as well as within neurons.
Reading, music and travelling are among my other interests.
ALUMNI
ALUMNI
Ph.D. Graduates
Ph.D. Graduates
Tushar Dubey(2015-2022)
PDF @ National Institute of Health, United States
Abhishek Balmik(2015-2021)
Shweta Sonawane(2014-2021)
PDF @ Institute of Neuropathiphysiology, CNRS
Aix-Marseille University
Marseille, France
Nalini Gorantla(2014-2021)
PDF @ MD Anderson Cancer Center, USA
Research Fellows and assistants
Ms. Tanuja Sarkar, Project assistant (DBT-Neuroscience)
M. Sc. Neuroscience (DBT), Jiwaji University, Gwalior, Madhya Pradesh.
Mrs. Lisni Sunny, Project assistant (DST-SERB)
M. Sc. Biochemistry, Bharathiyar University, Coimbatore, Tamil Nadu.
Project Trainees
Ms. Umamaheshwari Kadambari, M.Sc Intergrated Biotechnology, Bharathidasan University, Trichy, Tamilnadu.
Mr. Dhyey Vyas, M.Sc Intergrated Molecular Biology, M S Baroda University, Baroda, Gujarat.
Mr. Abhibroto Karmakar, M.Sc Medical Biotechnology, Calcutta School of Tropical Medicine, Kolkata, West Bengal.
Mr. A. Arokeyamychealsimon, M.Sc Biotechnology, Bharathiyar University, Coimbatore, Tamil Nadu.
Mr. Gopi VK, M.Sc Biotechnology, Bharathiyar University, Coimbatore, Tamil Nadu.
Mr. Palgun Raj, M.Sc Human Genetics, Andhara University (AU), Visakhapatnam, Andhara Pradesh.
Ms. Ragini Agarwal, M.Sc Biotechnology, Madurai Kamraj University (MKU), Tamilnadu.
Mr. Sayan Das, M.Sc Intergrated Molecular Biology, Mysore University, Karnataka.
Ms. Niveditha, M.Sc Biotechnology, Sastra University, Tamilnadu.
Ms. Urvi Goyal, M.Sc Biotechnology, Mata Gujri Mahila Rani Durgavati University, Madhya Pradesh.
Ms. Anjhu Nair, M.Sc Animal Science, Bharathidasan University , Tamilnadu.
Mr. Gokul Raja, M.Sc Biotechnology, Bharathiyar University, Tamilnadu.
Ms. Namrata Pai, M.Sc Medical Genetics, VIT University, Tamilnadu.
Ms. Ankita Ray M.Tech Biotechnology, VIT University, Tamilnadu.
Mr. Kunal Gode, M.Tech Biotechnology, VIT University, Tamilnadu.
Ms. Ananya Dey, M.Sc Biotechnology, Mumbai University, Maharasthra.
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