Manchester, U.K.

CREDIT: ALBERTO MANUEL UROSA TOLEDANO/GETTY IMAGES

Once famed for its towering industry and more recently, vibrant music scene, Manchester is now one of the fastest-growing cities in Europe, buoyed by an influx of digital and media companies. Servicing this boom are a number of upscale and design-led arrivals. The new Cultureplex, an ex-railway goods warehouse in the northern quarter, offers up a restaurant, bar, and café, alongside a constantly revolving program of film, visual arts, and performances. Opening this spring, Hotel Brooklyn, inspired by the New York City borough from which it gets its name, is housed in a Victorian brownstone. The team behind Chiltern Firehouse recently unveiled Native Manchester, a new multi-use 166-apartment hotel in the northern quarter. Meanwhile, chef du jour Tom Kerridge has opened an outpost in the new Stock Exchange hotel, a 40-room Relais & Chateaux property in a storied Edwardian Baroque building. Kerridge’s Bull & Bear restaurant serves smartly prepared British classics, such as crispy pig’s head with celeriac rémoulade. Epicureans are also flocking to Mana, which recently won the city’s first-ever Michelin star. The Nordic-leaning restaurant’s highlight is a 12- to 16-course tasting menu featuring morsels such as barbecued duck broth and lavender or yakitori-style eel with roasted yeast and blueberry. —Jemima Sissons