RESEARCH

RESEARCH INTERESTS

Microfluidics
Microfabrication
Computational analysis
Multiscale and Multiphysics

LABORATORY WORK EXPERIENCE

1. Computer Aided Engineering Lab (2021- Present)

• Currently working under the supervision of Dr. Linda Chen, Associate Professor, WSU, on hybrid techniques that combine the benefits of both inertia effects and active techniques such as dielectrophoresis (DEP) to differentiate among various types of cells based on both cell size and their dielectric properties.

• Developed a technique that utilized frequency-based external AC electric field and sheath flow, for accomplishing a continuous and high throughput separation of MDA-231 CTCs from overlapping sized WBCs.

• Modeled normal cells and cancer cells using biological and mechanical properties for the application of CTC separation microchannels (using COMSOL , SolidWorks, and MATLAB)

2. Cleanroom Lab - Class 100 (2022-Present)

Completed a course on Microfbarication and have hands-on experience in Film Deposition, Lithography, Etching, Soft Lithography, Thermal Oxidation and Optical profiler in Class 100 cleanroom.

3. Macro-to-Micro scale Fluids Engineering Lab (MμFEL) (2016-2017)

I worked at Macro-to-Micro scale Fluids Engineering Lab (MμFEL) of Professor Dr. A.B.M. Toufique Hasan under the supervision of Professor Dr. Mohammad Ali to perform numerical simulation on airfoil design for reducing drag.

Current Research on Microfluidic channel design for Circulating Tumor Cell separation

Inertial microfluidics, which has the capability for unconventional use of fluid inertia to separate different types of cells, is getting attention as a high-throughput microchip technique. Our interest in this area is to develop hybrid techniques that combine the benefits of both inertia effects and active techniques such as dielectrophoresis (DEP) to differentiate among various types of cells based on both cell size and their dielectric properties. By utilizing a frequency-based external AC electric field and sheath flow, our proposed technique could accomplish a continuous and high throughput separation of MDA-231 CTCs from overlapping sized WBCs.

CTC SEPARATION USING DEP BASED INERTIAL MICROFLUIDICS WITH A ZIGZAG CHANNEL

a) Both CTC and WBC are pushed down in the inlet using sheath flow.

b) Electrode frequency is set such that only WBC will feel electric force due to its dielectric property.

c) WBC will be pushed upward due to the electric field and separated from CTC.

PUBLICATION

[1] Islam, M. S., Uddin, M. R., Chen, X., 2022, ”Circulating Tumor Cell Separation in a Zigzag Channel Using Dielectrophoresis Based Inertial Microfluidics,” in ASME International Mechanical Engineering Congress and Exposition(IMECE), Ohio, Columbus, USA (Accepted)

[2] Islam, M. S., Chen, X., 2022, ”Separation of lung cancer cells using dielectrophoresis embedded hybrid curved contraction-expansion channel”, Manuscript submitted for publication.

[3] Islam, M. S., Chen, X., 2022, ”Separation of CTCs using dielectrophoresis embedded hybrid Zigzag channel with obstacles”, Manuscript in preparation.

[4] Islam, Md. S., Hakim, S. M., Ali, M., and Islam, Md. Q., 2017, “Numerical Investigation on Boundary Layer Control through Moving Surface in NACA 0012 Airfoil,” American Institute of Phyics(AIP) Conference Proceedings, 1851(1), p. 020111.

Previous Research (2016-2017)

UNDERGRADUATE THESIS

B.Sc. Thesis: NUMERICAL STUDY ON AERODYNAMIC CHARACTERISTICS OF NACA 0012 WITH MOVING SURFACE

Abstract: This study focuses on the aerodynamic characteristics and drag reduction by reducing adverse pressure gradient and delaying the flow separation of 2D NACA 0012 airfoil by moving surface. This investigation is done by numerical simulation using RANS equations. Two particular cases are considered. For 'single moving surface' only one moving surface of 10% of the chord length is placed at upper surface starting from 0.05c to 0.15c. For 'double moving surface', one moving surface of 10% of the chord length is placed at upper surface starting from 0.05c to 0.15c and one moving surface of same size is placed at lower surface from 0.05c to 0.15c. Momentum injection into the flow field moves the separation of boundary layer in the vicinity of trailing edge of the airfoil. By momentum injection through single moving upper surface with the surface velocity u/U =2 and for different angle of attack it is possible to reduce the average drag coefficient by 23.9%. For same condition with double moving surface it is possible to reduce the average drag coefficient by 25.9%. For moving surface boundary condition, boundary-layer separation is delayed along the chord length on the upper surface of the airfoil. Lift coefficient is quite same for no moving surface, single moving surface and double moving surface. The value of lift coefficient is increased very slightly for using single and double moving surface. For single and double moving surface, average increase of lift to drag coefficient ratio are 37.3% and 41% respectively.

Supervisor: Professor Dr. Mohammad Ali, Department of Mechanical Engineering, BUET.

Numerical Investigation on Boundary Layer Control through Moving Surface in NACA 0012 Airfoil