Publications

PubMed-NCBI: https://www.ncbi.nlm.nih.gov/pubmed/?term=((Rourke+JL%5BAuthor%5D)+AND+rourke+Jillian+L)+AND+rourke+J 

ResearchGate: https://www.researchgate.net/profile/Jillian-Rourke 

Mount Allison student authors denoted with *

• Cahill, H. F.*, Scott, B. S.*, Oni, P. O.*, Stapleton, G. V. L.*, MacCormack, T. J., Meli, M-V., and Rourke, J. L. (2024) Multiparametric cytotoxicity profiling reveals cell-line and ligand-dependent toxicity for pegylated gold nanoparticles (AuNP-PEG). https://cdnsciencepub.com/doi/10.1139/cjc-2023-0137 

• Power, M. E.*, Fernandez, N. F.*, Oni, P. O.*, Kalia, A.*, and Rourke, J. L. (2023) The non-nutritive sweeteners sucralose increases β-arrestin signaling at the constitutively active orphan G protein-coupled receptor GPR52. https://cdnsciencepub.com/doi/full/10.1139/cjpp-2023-0199

• Barrett, K. *, Dupuis, M.*, Crossman, A.*, Park, S.*, George, T., Vogels, C., Rourke, J., Masuda, J. D., and Westcott, S. A. (2023) Synthesis, characterization, and anticancer properties of iminopyridine platinum(II) complexes containing long aliphatic chains‡. https://cdnsciencepub.com/doi/abs/10.1139/cjc-2023-0031 

• Ngô, G. N.*, Park, S.*, Stack, H. M.*, Rourke, J., Melanson, J. A., and Westcott, S. A. (2023) A comparative study of boron-containing and boron-omitted capsaicinoids. https://cdnsciencepub.com/doi/full/10.1139/cjc-2023-0043 

• McDougall, R.*, Cahill, H.*, Power, M.*, MacCormack, T., Meli, V., and Rourke, J. (2022) Multiparametric cytotoxicity assessment: the effect of gold nanoparticle ligand functionalization on ovarian carcinoma cell death. https://www.tandfonline.com/eprint/F8SKUGE3KAMXKGVZDTDH/full?target=10.1080/17435390.2022.2095312

• Laprairie, R., Bagher, A., Rourke, J., Zrein, A., A. Cairns, E., Kelly, M., et al. (2019) Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington’s disease in the R6/2 mouse model. Neuropharmacology. https://www.sciencedirect.com/science/article/pii/S0028390819301133

• Cogger, K., Sinha, A., Sarangi, F., C. McGaugh, E., Saunders, D., Dorrell, C., Mejia-Guerrero, S., Aghazadeh, Y., Rourke, J., et al. (2017) Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors. Nature Communications 8. https://www.nature.com/articles/s41467-017-00561-0.pdf 

• Rourke, J., Hu, Q., and A. Screaton, R. (2017) AMPK and Friends: Central Regulators of β Cell Biology. Trends in Endocrinology & Metabolism 29. https://www.sciencedirect.com/science/article/pii/S1043276017301686

• Robitaille, K., Rourke, J., McBane, J., Fu, A., Baird, S., Du, Q., et al. (2016) High-Throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation. The Journal of biological chemistry 291. http://www.jbc.org/content/291/9/4614.full

• Clattenburg, L., Wigerius, M., Qi, J., Rainey, J., Rourke, J., Shanmugam, M., et al. (2015) NOS1AP functionally associates with YAP to regulate Hippo signaling. Molecular and cellular biology 35. https://mcb.asm.org/content/mcb/35/13/2265.full.pdf

• Dranse, H., Rourke, J., Stadnyk, A., and J Sinal, C. (2015) Investigating chemerin/CMKLR1 signalling as a novel link between obesity and inflammatory bowel disease. Endocrine Abstracts. https://www.endocrine-abstracts.org/ea/0037/ea0037gp.13.01

• Dranse, H., Rourke, J., Stadnyk, A., and J. Sinal, C. (2015) Local chemerin levels are positively associated with DSS-induced colitis but constitutive loss of CMKLR1 does not protect against development of colitis. Physiological Reports 3. https://physoc.onlinelibrary.wiley.com/doi/pdf/10.14814/phy2.12497

• Rourke, J.L., Dranse, H. J., & Sinal, C. J. (2015). CMKLR1 and GPR1 mediate chemerin signaling through the RhoA/ROCK pathway. Molecular and Cellular Endocrinology, 417, 36–51. https://www.sciencedirect.com/science/article/pii/S030372071530068X 

• Rourke, J.L., Muruganandan, S., Dranse, H. J., McMullen, N. M., & Sinal, C. J. (2014). Gpr1 is an active chemerin receptor influencing glucose homeostasis in obese mice. Journal of Endocrinology, 222(2), 201–215. https://www.researchgate.net/profile/Jillian_Rourke/publication/262843779_Gpr1_is_an_active_chemerin_receptor_influencing_glucose_homeostasis_in_obese_mice/links/560ebaed08ae6b29b499a351.pdf 

• Rourke, J. and Sinal, C.J. (2014) Biotransformation/Metabolism. Encyclopedia of Toxicology.

• Rourke, J.L., Dranse, H.J., and Sinal, C.J. (2013) Towards an integrative approach to understanding the role of chemerin in human health and disease. Obes Rev 14: 245–262. https://onlinelibrary.wiley.com/doi/pdf/10.1111/obr.12009

• Shanmugam, M., J Dranse, H., Rourke, J., Mcmullen, N., and J Sinal, C. (2013) Chemerin Neutralization Blocks Hematopoietic Stem Cell Osteoclastogenesis. Stem cells (Dayton, Ohio) 31. https://stemcellsjournals.onlinelibrary.wiley.com/doi/pdf/10.1002/stem.1450 

• Watts, S.W., Dorrance, A.M., Penfold, M.E., Rourke, J.L., Sinal, C.J., Seitz, B., et al. (2013) Chemerin connects fat to arterial contraction. Arterioscler. Thromb. Vasc. Biol. 33: 1320–1328. https://www.ahajournals.org/doi/full/10.1161/ATVBAHA.113.301476

• Ernst, M., Haidl, I., A Zúñiga, L., J Dranse, H., Rourke, J., A Zabel, B., et al. (2011) Disruption of the Chemokine-Like Receptor-1 (CMKLR1) Gene Is Associated with Reduced Adiposity and Glucose Intolerance. Endocrinology 153: 672–82. https://academic.oup.com/endo/article/153/2/672/2424412 

• Shanmugam, M., Parlee, S., Rourke, J., C Ernst, M., B Goralski, K., and J Sinal, C. (2011) Chemerin, a Novel Peroxisome Proliferator-activated Receptor (PPAR) Target Gene That Promotes Mesenchymal Stem Cell Adipogenesis. The Journal of biological chemistry 286: 23982–95. http://www.jbc.org/content/286/27/23982.full