Research Interests

• Cellular information processing

• Ligand discrimination

• Kinetic proofreading

• Immunological self/non-self discrimination

Publications

Paper

• Active thermodynamic force driven mitochondrial alignment,
  Masashi K. Kajita, Yoshiyuki Konishi, Tetsuhiro S. Hatakeyama*,
  Physical Review Research, 6, L022024, 2024. https://doi.org/10.1103/PhysRevResearch.6.L022024.

• Early dynamics of chronic myeloid leukemia on nilotinib predicts deep molecular response,
  Yuji Okamoto, Mitsuhito Hirano, Kai Morino,  Masashi K. Kajita*,  Shinji Nakaoka, Mayuko Tsuda, Kei-ji Sugimoto, Shigehisa Tamaki, Junichi Hisatake, Hisayuki Yokoyama, Tadahiko Igarashi, Atsushi Shinagawa, Takeaki Sugawara, Satoru Hara, Kazuhisa Fujikawa, Seiichi Shimizu, Toshiaki Yujiri, Hisashi Wakita, Kaichi Nishiwaki, Arinobu Tojo, Kazuyuki Aihara*.
  npj Systems Biology and Applications, 8, 39, 2022.  https://doi.org/10.1038/s41540-022-00248-3 (Open Access)

• Time-series clustering of single-cell trajectories in collective cell migration,
  Xin Zhuohan†, Masashi K. Kajita†, Keiko Deguchi, Shin-ichiro Suye, and Satoshi Fujita.
  Cancers, 14 (19), 4587, 2022.  https://doi.org/10.3390/cancers14194587 (Open Access, †: equally contribution)

• Intermitochondrial signaling regulates the uniform distribution of stationary mitochondria in axons,
  Nozomu Matsumoto, Ikuma Hori, Masashi K. Kajita, Tomoya Murase, Wataru Nakamura, Takahiro Tsuji, Seiji Miyake, Masaru Inatani, Yoshiyuki Konishi,
  Molecular and Cellular Neuroscience, 119, 103704, 2022. https://doi.org/10.1016/j.mcn.2022.103704 (50 days' free access).

• An error correction mechanism for reliable chemical communication systems,
  Masashi K. KAJITA*,
  The journal of Robotics, Networking and Artificial Life, 7 (1), 2020.  https://doi.org/10.2991/jrnal.k.200512.011 (Open Access)

• Reliable target ligand detection by noise-induced receptor cluster formation,
  Masashi K. Kajita*, Kazuyuki Aihara, Tetsuya J. Kobayashi,
  Chaos: An Interdisciplinary Journal of Nonlinear Science, 30 (1), 011104, 2020. https://doi.org/10.1063/1.5140714 (PDF)

• Balancing specificity, sensitivity, and speed of ligand discrimination by zero-order ultraspecificity,
  Masashi K. Kajita*, Kazuyuki Aihara, Tetsuya J. Kobayashi,
  Physical Review E, 96(1), 4065–14, 2017. http://doi.org/10.1103/PhysRevE.96.012405 (arXiv, PDF)

• Experimental and theoretical bases for mechanisms of antigen discrimination by T cells,
  Masashi K. Kajita*, Ryo Yokota, Kazuyuki Aihara, Tetsuya J. Kobayashi,
  BIOPHYSICS, 11, 85-92, 2015. http://doi.org/10.2142/biophysics.11.85

Misc.

• Quantitative biology of ligand discrimination by immune T cells,
  Masashi K. KAJITA*,
  SEISAN KENKYU,  71(2), 125-132, 2019.  https://doi.org/10.11188/seisankenkyu.71.125 (Japanese)

Award

• BIO UT 2015, Poster Presentation Award (June, 2015)

Society

• The Biophysical Society of Japan

• Japanese Society for Mathematical Biology

Education

• Ph.D. in Information Science and Technology, The University of Tokyo, Japan (March 23, 2017)

• Master of Science in Biological Information, Tokyo Institute of Technology, Japan  (March 26, 2012)

• Bachelor of Science, Tokyo Institute of Technology, Japan (March 26, 2010)

Research Position, Fellowship, Scholarship

• Senior Assistant Professor, Department of Applied Chemistry and Biotechnology, University of Fukui, Japan (April 2024 ~)

• Assistant Professor, Department of Applied Chemistry and Biotechnology, University of Fukui, Japan (March 2020 ~ March 2024)

• Research Associate, Institute of Industrial Science, The University of Tokyo, Japan (October 2017 ~ February 2020)

• Project Researcher (post-doc), Institute of Industrial Science, The University of Tokyo, Japan (April 2017 ~ September 2017)

• JSPS Research Fellow (DC2) (April 2014 ~ March 2016)

• Assistant Technical Staff, Institute of Industrial Science, The University of Tokyo, Japan  (April 2012 ~ March 2013)

• Master 21, Yoshida Scholarship Foundation  (April 2010 ~ March 2012)

Research Projects

• Pattern formation (2020~)

• Bioimage analysis (2020~)

• Medical data analysis (2018~)

• Theory of self/non-self discrimination & ligand discrimination of immune cells (2013~)

• Stochastic simulation of cellular signal transduction system, and bio-imaging  (2009~2012)

Research Grants

• JSPS KAKENHI Grant-in-Aid for Early-Career Scientists. (Principal Investigator, 2021~)

• JSPS KAKENHI Grant-in-Aid for Scientific Research (S). (Co-Investigator, 2019~2020)

• JSPS KAKENHI Grant-in-Aid for Early-Career Scientists. (Principal Investigator, 2018~2022)

• JSPS KAKENHI Grant-in-Aid for JSPS Fellows (DC2). (Principal Investigator, 2014~2016)

Links

• Researchmap

• University of Fukui, Researchers Database

• ORCiD

• Google Scholar

• Laboratory for Bio-process Engineering, Department of Applied Chemistry and Biotechnology, Faculty of Engineering, University of Fukui

• Laboratories for Mathematics, Lifesciences, and Informatics (Aihara Lab), Institute of Industrial Science, The University of Tokyo

• Laboratories for Quantitative Biology (Kobayashi Lab), Institute of Industrial Science, The University of Tokyo

Contact

Contact

masashi.k.kajita " at " gmail.com