flow–controlled ventilation will be investigated in these patient cohorts undergoing various surgical interventions.
The results of these investigations will serve as a foundation for future randomized clinical trials exploring the potential benefits of FCV across various clinical settings and patient populations. All findings from these physiological studies will undergo peer review and be published in PubMed-indexed journals.
This investigation will analyze intraoperative parameters and postoperative outcomes in patients ventilated with FCV during bariatric procedures. The retrospective analysis will include approximately 50 patients who underwent surgery at HOCH Health Ostschweiz, Cantonal Hospital St. Gallen, between 2023 and 2026.
This investigation has systematically reviewed and analyzed current publications on FCV to summarize existing evidence across diverse surgical and clinical settings. The review assessed study quality, methodology, and reported outcomes to identify consistent findings and gaps in current knowledge. By integrating data from both experimental and clinical studies, this systematic review provides a comprehensive overview of FCV’s efficacy, safety, and clinical applicability, thereby guiding future research and trial design.
published in the Journal of Clinical Anesthesia, 2026 doi:10.1016/j.jclinane.2026.112318
This is a post–hoc analysis of the PROFLOW–ROBOTic pilot trial investigating sex differences in mechanical power in robot–assisted laparoscopic surgery. The analysis examines whether the individualized nature of FCV mitigates known sex disparities associated with conventional ventilation strategies. The findings contribute to a better understanding of personalized mechanical ventilation and may help guide future research on sex–specific ventilatory management. This work served as the Master’s thesis of Lieve Jacobs at the University of Amsterdam, The Netherlands, in 2026.
This study aims to investigate whether reported differences in mechanical power between FCV and conventional mechanical ventilation depend on the methods used to measure airway pressure and calculate mechanical power. Particular attention will be given to the distinction between ventilator-derived airway pressure and directly measured intratracheal pressure. Through a systematic review of published studies, we aim to assess the comparability of mechanical power measurements across ventilation modes and determine whether methodological differences may explain conflicting findings. The results will help guide the design and interpretation of future studies investigating mechanical power and dissipated energy during FCV.