PUBLICATIONS

Ramesh Butti, Prachi Kapse, Garima Bhadhurya  , Amit S. Yadav, Suhail Ahmed, Rohan Chaubal, Pallavi Parab, Rasika Kadam, Amit Dutt, Sudeep Gupta, Gopal C Kundu: Development and characterization of a patient‑derived orthotopic xenograft of therapy‑resistant breast cancer . Oncology Reports, 2023 May; 49(5):99.  doi: 10.3892/or.2023.8536. Epub 2023 Mar 31 (IF: 4.2)

Tandrima Mitra, Soumya S Mahapatra, Barnalee Mishra, Venketesh K Panda, Diksha Malhotra, Anusuya Roy Chowdhury, and Gopal C Kundu . Hypoxia and its Biological Implications for Cancer Therapy. Springer Nature, Book Chapter, 2023

Pinaki Banerjee, Prachi Kapse, Shehnaz Siddique, Jasoda Choudhari, Varshasnata Mohanty, Suresh W Gosavi, Rajesh N Gacche, Gopal C Kundu. Therapeutic implications of cancer stem cells in prostate cancer. Cancer Biology and Medicine, 2023 (IF: 5.347)

Ramesh Butti and Gopal C Kundu. The molecular dialogue between the tumor cells and fibroblasts. Oncotarget, 2023 May 19;14:462-463. doi: 10.18632/oncotarget.28405 (IF: 5.168)

Murlidhar A Betallu , Shaileshkumar R Bhalara , Kailash B Sapnar , Vijay B Tadke, Keerti Meena , Ananya Srivastava , Gopal C Kundu , Mahadeo Gorain . Hybrid Inorganic Complexes as Cancer Therapeutic Agents: In-vitro Validation. Nanotheranostics. 2023 Mar 11;7(3):270-280. doi: 10.7150/ntno.81557. eCollection 2023. (IF: 5.28 )

Jasoda Choudhari , Ramakrishna Nimma , Snehal K Nimal , Santosh Kumar Totakura Venkata , Gopal C Kundu, Rajesh N Gacche. Prosopis juliflora (Sw.) DC phytochemicals induce apoptosis and inhibit cell proliferation signaling pathways, EMT, migration, invasion, angiogenesis and stem cell markers in melanoma cell lines. J Ethnopharmacol. 2023 Aug 10;312:116472. doi: 10.1016/j.jep.2023.116472. Epub 2023 Apr 14. (IF: 5.4)

N P Syamprasad, Siddhi Jain, Bishal Rajdev, Samir Ranjan Panda,  Jagadeesh Kumar Gangasani, Veerabhadra Swamy Challa, Jayathirtha Rao Vaidya, Gopal C Kundu, V G M Naidu. AKR1B1 inhibition using NARI-29-an Epalrestat analogue-alleviates Doxorubicin-induced cardiotoxicity via modulating Calcium/CaMKII/MuRF-1 axis. Chem Biol Interact. 2023 Aug 25;381:110566. doi: 10.1016/j.cbi.2023.110566. Epub 2023 May 29.PMID: 37257577 (IF: 5.168)

Soma Banerjee, Swagata Majumdar, Anannya Chakraborty, Sumit Das, Mahadeo Gorain, Soumyabrata Chatterjee, Indrashish Dey, Sayantani Bhowmik, Suchandrima Ghosh, Sanjana Banerjee, Sk Ahammed, Abhijit Chowdhury, Simanti Datta, Gopal C Kundu: Sponging of five tumour suppressor miRNAs by lncRNA-KCNQ1OT1 activates BMPR1A/BMPR1B-ACVR2A/ACVR2B signalling and promotes chemoresistance to hepatocellular carcinoma, 2023 (in press)

Rajendra Prasad, Bárbara B Mendes, Mahadeo Gorain, Gopal Chandra Kundu, Narendra Gupta, Berney Peng, Eaint Honey Aung Win, He Qing, João Conde: Bioinspired and biomimetic cancer-cell-derived membrane nanovesicles for preclinical tumor-targeted nanotheranostics, Cell Reports Physical Science, 2023, (IF: 8.9)

Das S, Bano S, Kapse P, Kundu GC. CRISPR based therapeutics: a new paradigm in cancer precision medicine. Mol Cancer. 2022 Mar 25;21(1):85. doi: 10.1186/s12943-022-01552-6. PMID: 35337340; PMCID: PMC8953071. 

Surve C, Banerjee A, S A, Chakraborty R, Kumar D, Butti R, Gorain M, Parida S, Kundu GC, Shidhaye S, Patnaik S. Antiproliferative and apoptotic potential of methotrexate lipid nanoparticles in a murine breast cancer model. Nanomedicine (Lond). 2022 May;17(11):753-764. doi: 10.2217/nnm-2021-0446. Epub 2022 May 16. PMID: 35575008. 

Radharani NNV, Yadav AS, Nimma R, Kumar TVS, Bulbule A, Chanukuppa V, Kumar D, Patnaik S, Rapole S, Kundu GC. Tumor-associated macrophage derived IL-6 enriches cancer stem cell population and promotes breast tumor progression via Stat-3 pathway. Cancer Cell Int. 2022 Mar 17;22(1):122. doi: 10.1186/s12935-022-02527-9. PMID: 35300689; PMCID: PMC8932105. 

Porwal A, Kundu GC, Bhagwat G, Butti R. Herbal medicine AnoSpray suppresses proinflammatory cytokines COX-2 and RANTES in the management of hemorrhoids, acute anal fissures and perineal wounds. Exp Ther Med. 2022 Jan;23(1):86. doi: 10.3892/etm.2021.11009. Epub 2021 Nov 25. PMID: 34938368; PMCID: PMC8688930. 

Butti R, Nimma R, Kundu G, Bulbule A, Kumar TVS, Gunasekaran VP, Tomar D, Kumar D, Mane A, Gill SS, Patil T, Weber GF, Kundu GC. Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Twist1 to promote breast cancer progression. Oncogene. 2021 Mar;40(11):2002-2017. doi: 10.1038/s41388-021-01663-2. Epub 2021 Feb 18. PMID: 33603163. 

Fnu G, Agrawal P, Kundu GC, Weber GF. Structural Constraint of Osteopontin Facilitates Efficient Binding to CD44. Biomolecules. 2021 May 30;11(6):813. doi: 10.3390/biom11060813. PMID: 34070790; PMCID: PMC8228714. 

Butti R, Kumar TVS, Nimma R, Banerjee P, Kundu IG, Kundu GC. Osteopontin Signaling in Shaping Tumor Microenvironment Conducive to Malignant Progression. Adv Exp Med Biol. 2021;1329:419-441. doi: 10.1007/978-3-030-73119-9_20. Erratum in: Adv Exp Med Biol. 2021;1329:C1-C2. PMID: 34664250. 

Choksi A, Parulekar A, Pant R, Shah VK, Nimma R, Firmal P, Singh S, Kundu GC, Shukla S, Chattopadhyay S. Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP1. Cancer Metab. 2021 Apr 16;9(1):16. doi: 10.1186/s40170-021-00252-x. PMID: 33863392; PMCID: PMC8052847. 

Ghuwalewala S, Ghatak D, Das S, Roy S, Das P, Butti R, Gorain M, Nath S, Kundu GC, Roychoudhury S. MiRNA-146a/AKT/β-Catenin Activation Regulates Cancer Stem Cell Phenotype in Oral Squamous Cell Carcinoma by Targeting CD24. Front Oncol. 2021 Oct 12;11:651692. doi: 10.3389/fonc.2021.651692. PMID: 34712602; PMCID: PMC8546321. 

Parulekar A, Choksi A, Taye N, Totakura KVS, Firmal P, Kundu GC, Chattopadhyay S. SMAR1 suppresses the cancer stem cell population via hTERT repression in colorectal cancer cells. Int J Biochem Cell Biol. 2021 Dec;141:106085. doi: 10.1016/j.biocel.2021.106085. Epub 2021 Sep 20. PMID: 34551340. 

Prasad R, Jain NK, Yadav AS, Jadhav M, Radharani NNV, Gorain M, Kundu GC, Conde J, Srivastava R. Ultrahigh Penetration and Retention of Graphene Quantum Dot Mesoporous Silica Nanohybrids for Image Guided Tumor Regression. ACS Appl Bio Mater. 2021 Feb 15;4(2):1693-1703. doi: 10.1021/acsabm.0c01478. Epub 2021 Jan 8. PMID: 35014516. 

Bandyopadhayaya S, Akimov MG, Verma R, Sharma A, Sharma D, Kundu GC, Gretskaya NM, Bezuglov VV, Mandal CC. N-arachidonoyl dopamine inhibits epithelial-mesenchymal transition of breast cancer cells through ERK signaling and decreasing the cellular cholesterol. J Biochem Mol Toxicol. 2021 Apr;35(4):e22693. doi: 10.1002/jbt.22693. Epub 2021 Jan 4. PMID: 33393692. 

Porwal A, Kundu GC, Bhagwat G, Butti R. Polyherbal formulation Anoac‑H suppresses the expression of RANTES and VEGF for the management of bleeding hemorrhoids and fistula. Mol Med Rep. 2021 Oct;24(4):736. doi: 10.3892/mmr.2021.12376. Epub 2021 Aug 20. PMID: 34414451; PMCID: PMC8404094. 

Chibh S, Katoch V, Kour A, Khanam F, Yadav AS, Singh M, Kundu GC, Prakash B, Panda JJ. Continuous flow fabrication of Fmoc-cysteine based nanobowl infused core-shell like microstructures for pH switchable on-demand anti-cancer drug delivery. Biomater Sci. 2021 Feb 9;9(3):942-959. doi: 10.1039/d0bm01386b. PMID: 33559658. 

Ghosh S, Dutta N, Banerjee P, Gajbhiye RL, Sareng HR, Kapse P, Pal S, Burdelya L, Mandal NC, Ravichandiran V, Bhattacharjee A, Kundu GC, Gudkov AV, Pal M. Induction of monoamine oxidase A-mediated oxidative stress and impairment of NRF2-antioxidant defence response by polyphenol-rich fraction of Bergenia ligulata sensitizes prostate cancer cells in vitro and in vivo. Free Radic Biol Med. 2021 Aug 20;172:136-151. doi: 10.1016/j.freeradbiomed.2021.05.037. Epub 2021 Jun 5. PMID: 34097996. 

Porwal A, Kundu GC, Bhagwat G, Butti R. Herbal medicine AnoSpray suppresses proinflammatory cytokines COX-2 and RANTES in the management of hemorrhoids, acute anal fissures and perineal wounds. Exp Ther Med. 2022 Jan;23(1):86. doi: 10.3892/etm.2021.11009. Epub 2021 Nov 25. PMID: 34938368; PMCID: PMC8688930. 

Butti R, Nimma R, Kundu G, Bulbule A, Kumar TVS, Gunasekaran VP, Tomar D, Kumar D, Mane A, Gill SS, Patil T, Weber GF, Kundu GC. Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Twist1 to promote breast cancer progression. Oncogene. 2021 Mar;40(11):2002-2017. doi: 10.1038/s41388-021-01663-2. Epub 2021 Feb 18. PMID: 33603163. 

Fnu G, Agrawal P, Kundu GC, Weber GF. Structural Constraint of Osteopontin Facilitates Efficient Binding to CD44. Biomolecules. 2021 May 30;11(6):813. doi: 10.3390/biom11060813. PMID: 34070790; PMCID: PMC8228714. 

Butti R, Kumar TVS, Nimma R, Banerjee P, Kundu IG, Kundu GC. Osteopontin Signaling in Shaping Tumor Microenvironment Conducive to Malignant Progression. Adv Exp Med Biol. 2021;1329:419-441. doi: 10.1007/978-3-030-73119-9_20. Erratum in: Adv Exp Med Biol. 2021;1329:C1-C2. PMID: 34664250. 

Choksi A, Parulekar A, Pant R, Shah VK, Nimma R, Firmal P, Singh S, Kundu GC, Shukla S, Chattopadhyay S. Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP1. Cancer Metab. 2021 Apr 16;9(1):16. doi: 10.1186/s40170-021-00252-x. PMID: 33863392; PMCID: PMC8052847. 

Ghuwalewala S, Ghatak D, Das S, Roy S, Das P, Butti R, Gorain M, Nath S, Kundu GC, Roychoudhury S. MiRNA-146a/AKT/β-Catenin Activation Regulates Cancer Stem Cell Phenotype in Oral Squamous Cell Carcinoma by Targeting CD24. Front Oncol. 2021 Oct 12;11:651692. doi: 10.3389/fonc.2021.651692. PMID: 34712602; PMCID: PMC8546321. 

Parulekar A, Choksi A, Taye N, Totakura KVS, Firmal P, Kundu GC, Chattopadhyay S. SMAR1 suppresses the cancer stem cell population via hTERT repression in colorectal cancer cells. Int J Biochem Cell Biol. 2021 Dec;141:106085. doi: 10.1016/j.biocel.2021.106085. Epub 2021 Sep 20. PMID: 34551340. 

Prasad R, Jain NK, Yadav AS, Jadhav M, Radharani NNV, Gorain M, Kundu GC, Conde J, Srivastava R. Ultrahigh Penetration and Retention of Graphene Quantum Dot Mesoporous Silica Nanohybrids for Image Guided Tumor Regression. ACS Appl Bio Mater. 2021 Feb 15;4(2):1693-1703. doi: 10.1021/acsabm.0c01478. Epub 2021 Jan 8. PMID: 35014516. 

Bandyopadhayaya S, Akimov MG, Verma R, Sharma A, Sharma D, Kundu GC, Gretskaya NM, Bezuglov VV, Mandal CC. N-arachidonoyl dopamine inhibits epithelial-mesenchymal transition of breast cancer cells through ERK signaling and decreasing the cellular cholesterol. J Biochem Mol Toxicol. 2021 Apr;35(4):e22693. doi: 10.1002/jbt.22693. Epub 2021 Jan 4. PMID: 33393692. 

Porwal A, Kundu GC, Bhagwat G, Butti R. Polyherbal formulation Anoac‑H suppresses the expression of RANTES and VEGF for the management of bleeding hemorrhoids and fistula. Mol Med Rep. 2021 Oct;24(4):736. doi: 10.3892/mmr.2021.12376. Epub 2021 Aug 20. PMID: 34414451; PMCID: PMC8404094. 

Chibh S, Katoch V, Kour A, Khanam F, Yadav AS, Singh M, Kundu GC, Prakash B, Panda JJ. Continuous flow fabrication of Fmoc-cysteine based nanobowl infused core-shell like microstructures for pH switchable on-demand anti-cancer drug delivery. Biomater Sci. 2021 Feb 9;9(3):942-959. doi: 10.1039/d0bm01386b. PMID: 33559658. 

Ghosh S, Dutta N, Banerjee P, Gajbhiye RL, Sareng HR, Kapse P, Pal S, Burdelya L, Mandal NC, Ravichandiran V, Bhattacharjee A, Kundu GC, Gudkov AV, Pal M. Induction of monoamine oxidase A-mediated oxidative stress and impairment of NRF2-antioxidant defence response by polyphenol-rich fraction of Bergenia ligulata sensitizes prostate cancer cells in vitro and in vivo. Free Radic Biol Med. 2021 Aug 20;172:136-151. doi: 10.1016/j.freeradbiomed.2021.05.037. Epub 2021 Jun 5. PMID: 34097996. 

Porwal A, Kundu GC, Bhagwat G, Butti R. Herbal medicine AnoSpray suppresses proinflammatory cytokines COX-2 and RANTES in the management of hemorrhoids, acute anal fissures and perineal wounds. Exp Ther Med. 2022 Jan;23(1):86. doi: 10.3892/etm.2021.11009. Epub 2021 Nov 25. PMID: 34938368; PMCID: PMC8688930. 

Taware R, Taunk K, Kumar TVS, Pereira JAM, Câmara JS, Nagarajaram HA, Kundu GC, Rapole S. Extracellular volatilomic alterations induced by hypoxia in breast cancer cells. Metabolomics. 2020 Jan 24;16(2):21. doi: 10.1007/s11306-020-1635-x. PMID: 31980945. 

Prasad R, Jain NK, Yadav AS, Chauhan DS, Devrukhkar J, Kumawat MK, Shinde S, Gorain M, Thakor AS, Kundu GC, Conde J, Srivastava R. Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near-infrared light mediated cancer therapy. Commun Biol. 2020 Jun 5;3(1):284. doi: 10.1038/s42003-020-1016-z. PMID: 32504032; PMCID: PMC7275035. 

Nath S, Mondal S, Butti R, Prasanna Gunasekaran V, Chatterjee U, Halder A, Kundu GC, Mandal C. Desialylation of Sonic-Hedgehog by Neu2 Inhibits Its Association with Patched1 Reducing Stemness-Like Properties in Pancreatic Cancer Sphere-forming Cells. Cells. 2020 Jun 21;9(6):1512. doi: 10.3390/cells9061512. PMID: 32575925; PMCID: PMC7349614. 

Yadav AS , Radharani NNV , Gorain M , Bulbule A , Shetti D , Roy G , Baby T , Kundu GC . RGD functionalized chitosan nanoparticle mediated targeted delivery of raloxifene selectively suppresses angiogenesis and tumor growth in breast cancer. Nanoscale. 2020 May 21;12(19):10664-10684. doi: 10.1039/c9nr10673a. Epub 2020 May 6. PMID: 32374338. 

Tomar D, Yadav AS, Kumar D, Bhadauriya G, Kundu GC. Non-coding RNAs as potential therapeutic targets in breast cancer. Biochim Biophys Acta Gene Regul Mech. 2020 Apr;1863(4):194378. doi: 10.1016/j.bbagrm.2019.04.005. Epub 2019 Apr 29. PMID: 31048026. 

Sneha Mahalunkar, Amit Singh Yadav, Mahadeo Gorain, Vinay Pawar, Ranveig Braathen, Siegfried Weiss, Bjarne Bogen , Suresh W. Gosavi and Gopal C. Kundu. Functional Design of pH Responsive Folate Targeted Polymer Coated Gold Nanoparticles for Drug Delivery in Breast Cancer. Int J Nanomedicine. 2019 Oct 15; 14:8285-8302. doi: 10.2147/IJN.S215142. eCollection 2019. (IF:7.033)

Ashwini Wali, Mahadeo Gorain, Satish Inamdar, Gopal Kundu, and Manohar Badiger: In Vivo Wound Healing Performance of Halloysite Clay and Gentamicin-Incorporated Cellulose Ether-PVA Electrospun Nanofiber Mats. ACS Applied Bio Materials, (in press), 2019 (IF:0.746)

Romen Meitei Lourembam,  Amit Singh Yadav , Gopal C. Kundu & Pranab Behari Mazumder: Curcuma zedoaria (christm.) roscoe inhibits proliferation of MDA-MB231 cells via caspase-cascade apoptosis. Oriental Pharmacy and Experimental Medicine. 19, 235–241(2019) (IF:2.0)