PATHOL 4014A: amyotrophic lateral sclerosis (ALS)

Welcome to the supplemental Online Western Learning site for PATHOL 4014A: PathALS (Pathology of ALS). This course will explore the neurodegenerative disorder ALS, delving into modules of etiology, pathogenesis, signs and symptoms, treatment, and genetics. The aim of this course is to teach non-science students about the specifics of this disease in an engaging and thorough manner.

Please see the official OWL Brightspace page for syllabus, detailed schedule, and gradebook entries.

Schedule of lecture content:
Week 1 and 2: Etiology
Week 3 and 4: Pathology
Week 5 and 6: Signs and Symptoms
Week 7: Reading Week
Week 8 and 9: Treatment
Week 9 and 10: Genetics
Week 11: Exam Review
Week 12: Exam Period

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive neurodegenerative disorder characterized by the loss of upper and lower motor neurons. This degeneration leads to muscle weakness, atrophy, and eventual paralysis.

Please see the navigation below for bi-weekly modules. The content on this supplemental OWL site accompanies content taught in lecture and covered in the course textbook. Please ensure you are attending lecture and reading the assigned textbook sections to prepare for assignments and exams.

Pathogenesis

Signs and Symptoms

Treatment

Genetics

As an introduction to ALS, take a look at this video which briefly explains the disease:

Zero to Finals. (2024, January 8). Understanding Motor Neurone Disease [Video]. Youtube. https://youtu.be/dg_DntAnU8M?si=ma_nrRXMSXwyC3f2

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