Program

Reception Open 

Opening Remarks 

***1. THE EMBO KEYNOTE LECTURE
Thomas Langer (MPI-AGE, Germany, EMBO Member)
Nucleotide imbalance and mitochondrial innate immune signaling***

3. Stress Responses

1. 16:30 - 17:00
   Ye Tian (Institute of Genetics and Developmental Biology, China)
   Neuronal Regulation of Mitochondrial Stress Response and Systemic Aging

2. 17:00 - 17:30
   Christian Münch (Goethe University, Germany)
   Mitochondrial proteostasis signaling during stress and senescence

3. 17:30 - 18:00
   Mashun Onishi (The University of Osaka, Japan)
   Roles of mitochondrial retrograde signalling in ferroptotic resistance

4. 18:00 - 18:30
   Kunio Nakatsukasa (Nagoya City University, Japan)
   Cellular response pathways handling with ectopic metabolic stress

4. Metabolism & Diseases

1. 9:00 - 9:30
   Noriyuki Matsuda (Institute of Science Tokyo, Japan)
   Dysfunctional mitochondrial metabolism linked to Parkinson's disease

2. 10:00 - 10:30
   Tasneem Qaqorh (National Cerebral and Cardiovascular Center, Japan)
   Single-cell and spatial transcriptomics to identify mitochondrial disease progression and treatment targets

Group Photo in the Seminar Room & Coffee break

5. Short Talk #1 Selected from Poster Abstracts

1. 10:30 - 10:45
   Taisei Wakigawa (RIKEN, Japan)
   Mitochondrial ribotoxic stress triggers retrograde signaling for proteostasis maintenance

2. 10:45 - 11:00
   Hiromi Yamazaki (The University of Osaka , Japan)
   Regulation by selenoproteins governs hematopoietic stem cell function and lineage commitment

3. 11:00 - 11:15
   Takahiro Nagao (The University of Tokyo, Japan)
   PDZD8 induces Mitochondria-ER contact sites via IDR-dependent liquid-liquid phase separation

4. 11:15 - 11:30
   Busu Li (Qilu Hospital of Shandong University, China)
   Single-fiber proteomics reveals fiber-specific compensatory responses in m.3243A>G mitochondrial myopathy

7. Casual Poster Discussion
Poster Number: 1-30

  and Poster Clinic for selected posters by EMBO

8. Short Talk #2 Selected from Poster Abstracts 

1. 13:30 - 13:45
   Qian Zhang (Institute of Genetics and Developmental Biology, China)
   FUBL-3/FUBP1 couples mitochondrial stress to chromatin remodeling and longevity via the nurd complex

2. 13:45 - 14:00
   Matthew P. Challis (Monash University, Australia)
   Proximity labelling of the BAK macropore implicates the inner mitochondrial membrane protein SLC35a4-MP in apoptosis

3. 14:00 - 14:15
   Yuina Otani (Tokyo University of Science, Japan)
   Mitochondrial Intermediate Peptidase (MIPEP) regulates proteostasis via maturating proteases: ClpXP and m-AAA

4. 14:15 - 14:30
   Yuto Ishikawa (Gakushuin University, Japan)
   Conversion of MICOS/MIB complex contributes to cristae density during heart development

10. Stress Tolerance Mechanisms

1. 17:00 - 17:30
   Hiromi Sesaki (Johns Hopkins University, USA)
   Mitochondrial dynamics as a safeguard counteracting mitochondrial metabolic stress

2. 17:30 - 18:00
   Yilin Kang (University of Melbourne, Australia)
   Viral infection triggers tissue-specific manifestations of mitochondrial disease

3. 18:00 - 18:30
   Sae Tanaka (Keio University, Japan)
   Focusing on tardigrades and its tolerance mechanisms under extreme environments

13. Casual Poster Discussion

Poster Number: 31-60

and Poster Clinic for selected posters by EMBO

15. Cell Death and Lipid Environment

1. 15:00 - 15:30
   Natsuki Shinoda (University of Tokyo, Japan)
   Early-peaking caspase activity at the plasma membrane drives apoptotic phosphatidylserine exposure 

2. 15:30 - 16:00
   Soni Deshwal (Helmholtz Münich, Germany)
   Regulation of coenzyme Q synthesis and its export beyond mitochondria

3. 16:00 - 16:30
   Yohsuke Ohba (Keio University, Japan)
   Uncovering the state and fate of cells/organelles via organelle lipidomics