Liver Lipid Metabolism Physiological Map
Embedded Files
The Liver Lipid Metabolism Physiological Map is constructed through the curation of literature evidence and pathway resources. This map focuses on the underlying undisturbed physiological processes that drive the lipid metabolism in the liver. This work is performed in close collaboration with domain experts and it is being developed to study chemical-induced steatosis in the ONTOX project.
Navigate the interactive map on MINERVA.
Download the Liver Lipid Metabolism PM files.
Check the map documentation.
Curation and domain expert team:
Luiz Ladeira, PhD (Curator; Postdoctoral Researcher at the GIGA In Silico Medicine, University of Liège, Liège, Belgium);
Anouk Verhoeven (Domain expert; PhD Researcher at the Department of In Vitro Toxicology and Dermato-cosmetology, Vrije Universiteit Brussel, Belgium);
Julen Sans Serrano, PhD (Domain expert; Postdoctoral Researcher at the Department of In Vitro Toxicology and Dermato-cosmetology, Vrije Universiteit Brussel, Belgium);
Bernard Staumont, PhD (Curator; Project Manager and Postdoctoral Researcher at the GIGA In Silico Medicine, University of Liège, Liège, Belgium);
Alessio Gamba, PhD (Curator; Postdoctoral Researcher at the GIGA In Silico Medicine, University of Liège, Liège, Belgium);
Ramiro Jover, PhD (Domain expert; Professor at Department of Biochemistry, University of Valencia, IIS Hosp. La Fe, CIBERehd, Spain);
Anna Rapisarda, PhD (Domain expert; Project Manager and Postdoctoral Researcher at Department of Biochemistry, University of Valencia, IIS Hosp. La Fe, CIBERehd, Spain);
Tamara Vanhaecke, PhD (Domain expert; Professor at the Department of In Vitro Toxicology and Dermato-cosmetology, Vrije Universiteit Brussel, Belgium);
Mathieu Vinken, PhD (Domain expert; ONTOX coordinator; Professor at the Department of In Vitro Toxicology and Dermato-cosmetology, Vrije Universiteit Brussel, Belgium);
Liesbet Geris, PhD (Curator team PI; ONTOX PMs task leader; Head of the Biomechanics Research Unit, Professor at University of Liège and KU Leuven, Belgium).
Former contributors:
Jian Jiang, PhD (Domain expert);
Jonas van Ertvelde (Domain expert).
How to cite:
Ladeira, L., Verhoeven, A., van Ertvelde, J., Jiang, J., Gamba, A., Sanz Serrano, J., Vanhaecke, T., Heusinkveld, H., Jover, R., Vinken, M., Geris, L., & Staumont, B. (2025). Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding. Frontiers in Toxicology, 7, 1619651. https://doi.org/10.3389/ftox.2025.1619651
Page updated
Google Sites
Report abuse