How does atypical language lateralization develop? What are its consequences?
This project continues work conducted over the past four years, aiming to deepen previous findings on neurodevelopment and the challenges of obtaining a sufficiently large sample of healthy individuals with atypical language lateralization. Our research highlights two key factors: the corpus callosum and musical training.
A larger corpus callosum, previously linked to reduced functional lateralization in right-handed individuals, has also been associated with a higher likelihood of atypical language lateralization in our studies. Additionally, in a novel finding, we have identified that early musical training combined with left-handedness increases the predisposition to atypical language lateralization.
This project aims to explore the role of two key factors—corpus callosum and musical training—in the development of atypical language lateralization through three main objectives:
Expand the sample of left-handed adults with atypical language lateralization to conduct analyses of language network topology and neurogenetics.
Collect data from left-handed children and adolescents to examine the impact of factors such as music and interhemispheric connectivity on language lateralization development.
Study the neurobehavioral consequences of atypical language lateralization.
This research has implications across various fields, including:
Understanding cognitive function development through language studies.
Identifying the causes and effects of atypical language lateralization.
Gaining insights into the mechanisms of left-handedness.
Exploring the brain mechanisms underlying neurodevelopmental disorders such as schizophrenia, autism, dyslexia, and temporal lobe epilepsy.