Publications
Pre-print: Bhagaban Mallik, Shikha Kushwaha, Anjali Bisht, Harsha MJ, Andrew C Frank and Vimlesh Kumar. (2023). Arf GAP containing dAsap regulates NMJ organization and synaptic calcium through Arf6- dependent signaling in Drosophila. 10.1101/2023.06.30.547304. (Under communication)
Shefali Mishra, Vijaya Verma, Sambit Pradhan ,Manish Dwivedi, Pooja Jorwal, Varun Gowda, Madavan Vasudevan, Sujit Sikdar, Vimlesh Kumar, Pakkirisamy Thilagar, James Clement and Upendra Nongthomba (2024). Urolithin A mitigates behavioral and synaptic deficits associated with epilepsy through VDAC-1 inhibition: A novel treatment approach (Under review, Comm)
Pre-print: Anjali Bisht, Srikanth Pippadpally, Snehasis Majumder, Athulya T Gopi, Abhijeet Das, Chandan Sahi, Mani Ramaswami, Vimlesh Kumar. (2024). Prefoldin 5 is a microtubule-associated protein that suppresses Tau aggregation and neurotoxicity. doi: https://doi.org/10.1101/2024.10.14.618171. (Under review, eLife)
Pre-print: Srikanth Pippadpally, Saumitra Dey Choudhury, Anjali Bisht, Manish Kumar Dwivedi, Zeeshan Mushtaq, Suneel Reddy-Alla, Vimlesh Kumar. Endocytosis restricts synapse growth by attenuating Highwire/PHR1-dependent JNK signaling in a pathway parallel to the BMP signaling. doi: https://doi.org/10.1101/2024.11.03.621782. (Under communication)
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26. Bhagaban Mallik, Srikanth Pippadpally, Anjali Bisht, Sajad Bhat and Vimlesh Kumar. (2024). Distinct Bin/Amphiphysin/Rvs (BAR) family proteins may assemble on the same tubule to regulate membrane organization in vivo. Heliyon, https://doi.org/10.1016/j.heliyon.2024.e33672
25. Chitre, K., Kairamkonda, S., Dwivedi, M. K., Yadav, S., Kumar, V., Sikdar, S. K., & Nongthomba, U. (2024). Beadex, the Drosophila LIM only protein, is required for the growth of the larval neuromuscular junction. Journal of neurophysiology, 10.1152/jn.00064.2024. Advance online publication. https://doi.org/10.1152/jn.00064.2024
24. Kushwaha, S., Mallik, B., Bisht, A., Mushtaq, Z., Pippadpally, S., Chandra, N., Das, S., Ratnaparkhi, G., & Kumar, V. (2024). dAsap regulates cellular protrusions via an Arf6-dependent actin regulatory pathway in S2R+ cells. FEBS letters, 10.1002/1873-3468.14954. Advance online publication. https://doi.org/10.1002/1873-3468.14954
23. Saumitra Dey Choudhury, Manish Kumar Dwivedi, Srikanth Pippadpally, Abhinandan Patnaik, Shirish Mishra, Raghu Padinjat and Vimlesh Kumar (2022). AP2 Regulates Thickveins Trafficking to Attenuate NMJ Growth Signaling in Drosophila. eNeuro, 9(5), ENEURO.0044-22.2022. https://doi.org/10.1523/ENEURO.0044-22.2022
22. Bhagaban Mallik, Sajad Bhat and Vimlesh Kumar. (2022). Role of Bin‐Amphiphysin‐Rvs (BAR) domain proteins in mediating neuronal signaling and disease. Synapse. 76. 10.1002/syn.22248.
21. Maneesha Sinha, Ankita Shree, Kumar Singh, Kamal Kumar, Shreenivas Singh, Vimlesh Kumar and Praveen Verma (2021). Modulation of fungal virulence through CRZ1 regulated F-BAR-dependent actin remodeling and endocytosis in chickpea infecting phytopathogen Ascochyta rabiei. PLoS Genetics. 17. e1009137. 10.1371/journal.pgen.1009137.
20. Sajad Bhatt, Aadil Dhar, Zeeshan Mushtaq, Vimlesh Kumar and Abrar Qurashi. (2021). Fragile X Premutation rCGG Repeats Impair Synaptic Growth and Synaptic Transmission at Drosophila larval Neuromuscular Junction. Human Molecular Genetics. 30. 10.1093/hmg/ddab087.
19. Anangha Basargekar, Shweta Yogi, Zeeshan Mushtaq, Senthilkumar Deivasigamani, Vimlesh Kumar, Girish Ratnaparkhi and Anuradha Ratnaparkhi (2020). Dmon1 and rab7 interact to regulate glutamate receptor GluRIIA levels at the larval Drosophila neuromuscular junction. The International Journal of Developmental Biology 10.1101/2020.03.21.999524.
18. Saurabh Mehta, Vimlesh Kumar and Ram Kumar Mishra. (2020). Drosophila ELYS Regulates Dorsal Dynamics during Development. Journal of Biological Chemistry. 295. jbc.RA119.009451. 10.1074/jbc.RA119.009451.
17. Book Chapter: Sajad Bhatt and Vimlesh Kumar (2019). Modeling Hereditary Spastic Paraplegias in Fruit Flies: Potential of Its Genetic Paraphernalia. 10.1007/978-981-13-2218-1_14.
16. Bhagaban Mallik, Aditi Rajasekhar, Vimlesh Kumar*, Jeyaraman Sakar*. (2019). A Cell-Permeant Small Molecule for Super-Resolution Imaging of Endoplasmic Reticulum in Live Cells. Organic & Biomolecular Chemistry. https://doi.org/10.1039/C9OB00408D
15. Hamid, Runa, Hajirnis Nikhil, Kushwaha Shikha, Saleem Sadaf, Vimlesh Kumar and Rakesh Mishra. (2018). Drosophila Choline transporter non-canonically regulates pupal eclosion and NMJ integrity through a neuronal subset of mushroom body. Developmental Biology. 446. 10.1016/j.ydbio.2018.12.006.
14. Ruchika Mishra, Zeeshan Mushtaq, Bhagaban Mallik, Ramprasad, Vimlesh Kumar* and Jeyaraman Sankar* (2018). Selective Imaging of Lipids in Adipocytes Using an Imidazolyl Derivative of Perylenebisimide. ChemBioChem. 19. 10.1002/cbic.201800134.
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13. Bhagaban Mallik and Vimlesh Kumar. (2017). Regulation of actin-Spectrin cytoskeleton by ICA69 at the Drosophila neuromuscular junction. Communicative & integrative biology. 10.1080/19420889.2017.1381806.
12. Sandeep Raut, Bhagaban Mallik, Arpan Parichha, Amrutha V, Chandan Sahi* and Vimlesh Kumar* (2017) RNAi-mediated Reverse Genetic Screen Identified Drosophila Chaperones in Regulating Eye and Neuromuscular Junction Morphology: G3: Genes, Genomes and Genetics, doi: 10.1534/g3.117.041632.
11. Bhagaban Mallik, Manish Kumar Dwivedi, Zeeshan Mushtaq, Manisha Kumari, Praveen Kumar Verma and Vimlesh Kumar (2017). Regulation of Neuromuscular Junction Organization by Rab2 and Its Effector ICA69 in Drosophila: Development, doi: 10.1242/dev.145920.
10. Saumitra Dey Choudhury, Ancy VS, Zeeshan Mushtaq and Vimlesh Kumar (2017). Altered Translational Repression of an RNA-binding Protein, elav by AOA2-causative Senataxin Mutation Synapse, doi: 10.1002/syn.21969.
9. Zeeshan Mushtaq, Saumitra Dey Choudhury, Sri Krishna Gangwar, Genny Orso and Vimlesh Kumar (2016) Human Senataxin Modulates Structural Plasticity of the Neuromuscular Junction in Drosophila through a Neuronally Conserved TGFβ Signalling Pathway Neurodegener Dis, 16:324–336.
8. Saumitra Dey Choudhury, Zeeshan Mushtaq, Suneel Reddy-Alla, Sruthi S Balakrishnan, Rajan S Thakur, KS Krishnan, Padinjat Raghu, Mani Ramaswami and Vimlesh Kumar (2016). s2-adaptin Facilitates Basal Synaptic Transmission and is required for Regenerating Endo- Exo Cycling Pool under High Frequency Nerve Stimulation in Drosophila GENETICS 2016 10.1534/genetics.115.183863.
7. Remembering KS Krishnan (1946–2014) R Rikhy, V Kumar, A Basole, S Sanyal, Journal of neurogenetics 29 (1), 1-3 (We remember our PhD mentor Late Prof. KS Krishnan).
6. Maria Giovanna Rossetto, Erica Zanarella, Genny Orso, Michele Scorzeto, Aram Megighian, Vimlesh Kumar, Antonio V Delgado-Escueta, Andrea Daga (2011). Defhc1.1, a homologue of the juvenile myoclonic gene EFHC1, modulates architecture and basal activity of the neuromuscular junction in Drosophila. Human Molecular Genetics , 2011; 20(21):4248-57.
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5. Vimlesh Kumar*, Robert Frike, Debjani Bhar, Suneel Reddi-Alla, KS Krishnan, Sven Bogdan and Mani Ramaswami* (2009). The F-BAR Protein Syndapin Promotes Formation of Postsynaptic Membrane System in Drosophila Mol Biol of the Cell
4. Susy Kim, Vimlesh Kumar, Willie Lin, Shanker Karunanithi and Mani Ramaswami (2009). Reserve pool mobilization, not increased active zone number, underlies long-term facilitation at the Drosophila neuromuscular junction. Proc Natl Acad Sci USA 106(10), pp 4000-4005.
3. Vimlesh Kumar*, Suneel Reddi Alla, K.S, Krishnan and Mani Ramaswami* (2009). Syndapin is dispensable for synaptic vesicle endocytosis at the Drosophila larval neuromuscular junction. Mol. Cell. Neuroscience 40 (2), pp 233-240.
2. Vimlesh Kumar and Mani Ramaswami (2006). Kissing and Pinching: Synaptotagmin and Calcium do more between bilayers, Neuron, April 6, 2006, 50 pp 3-5
1. Richa Rikhy *, Vimlesh Kumar*, Rohit Mittal and K.S. Krishnan (2002). Endophilin is critically required for synapse function and formation in Drosophila melanogaster, J. Neurosci, 2002, 22 (17) 7478-7484.