Publications

Selected publications 2010-2024

2024

Llaó-Cid C, Peguera B, Kobialka P, Decker L, Vogenstahl J, Alivodej N, Srivastava S, Jin J, Kirchmaier BC, Milla C, Schlierbach H, Schänzer A, Acker T, Segarra M, Acker-Palmer A. Vascular FLRT2 regulates venous-mediated angiogenic expansion and CNS barriergenesis. Nat Commun. 2024 Nov 29;15(1):10372. doi: 10.1038/s41467-024-54570-x. link 

Acker-Palmer A. Guiding axon regeneration: Instructions from blood vessels. Neuron. 2024 Jan 17;112(2):175-177. doi: 10.1016/j.neuron.2023.11.017. link 

2022

Johanna Vogenstahl, Marta Parrilla, Amparo Acker-Palmer and Marta Segarra. Vascular Regulation of Developmental Neurogenesis. Front. Cell Dev. Biol. 2022 May 30. DOI: 10.3389/fcell.2022.890852. link

2021

Segarra M, Aburto MR, Acker-Palmer A. Blood-Brain Barrier Dynamics to Maintain Brain Homeostasis. Trends Neurosci. 2021 Jan 7:S0166-2236(20)30286-1. doi: 10.1016/j.tins.2020.12.002. Epub ahead of print. PMID: 33423792. link 

Bissen D, Kracht MK, Foss F, Hofmann J, Acker-Palmer A. EphrinB2 and GRIP1 stabilize mushroom spines during denervation-induced homeostatic plasticity. Cell Rep. 2021 Mar 30;34(13):108923. doi: 10.1016/j.celrep.2021.108923. PMID: 33789115; PMCID: PMC8028307. link 

2020

Volz C, Breid S, Selenz C, Zaplatina A, Golfmann K, Meder L, Dietlein F, Borchmann S, Chatterjee S, Siobal M, Schöttle J, Florin A, Koker M, Nill M, Ozretić L, Uhlenbrock N, Smith S, Büttner R, Miao H, Wang B, Reinhardt HC, Rauh D, Hallek M, Acker-Palmer A, Heukamp LC, Ullrich RT. (2020) Inhibition of tumor VEGFR2 induces Serine 897 EphA2-dependent tumor cell invasion and metastasis in NSCLC. Cell Rep. 31(4):107568. link

Gritsenko PG, Atlasy N, Dieteren CEJ, Navis AC, Venhuizen JH, Veelken C, Schubert D, Acker-Palmer A, Westerman BA, Wurdinger T, Leenders W, Wesseling P, Stunnenberg HG, Friedl P. p120-catenin-dependent collective brain infiltration by glioma cell networks. (2020) Nat Cell Biol. 22(1):97-107. link

2019

Harde E, Nicholson L, Furones Cuadrado B, Bissen D, Wigge S, Urban S, Segarra M, Ruiz de Almodóvar C, Acker-Palmer A. (2019) EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development. Elife. 8:e49819. link

Luck R, Urban S, Karakatsani A, Harde E, Sambandan S, Nicholson L, Haverkamp S, Mann R, Martin-Villalba A, Schuman EM, Acker-Palmer A, Ruiz de Almodóvar C. (2019) VEGF/VEGFR2 signaling regulates hippocampal axon branching during development. Elife. 8:e49818. link

Segarra M, Aburto MR, Hefendehl J, Acker-Palmer A. (2019) Neurovascular Interactions in the Nervous System. Annu Rev Cell Dev Biol. 35:615-635. link

Bissen D, Foss F, Acker-Palmer A. (2019) AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking. Cell Mol Life Sci. 76(11):2133-2169. link

Pan C, Schoppe O, Parra-Damas A, Cai R, Todorov MI, Gondi G, von Neubeck B, Böğürcü-Seidel N, Seidel S, Sleiman K, Veltkamp C, Förstera B, Mai H, Rong Z, Trompak O, Ghasemigharagoz A, Reimer MA, Cuesta AM, Coronel J, Jeremias I, Saur D, Acker-Palmer A, Acker T, Garvalov BK, Menze B, Zeidler R, Ertürk A. (2019) Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body. Cell. 179(7):1661-1676.e19. link

2018

Segarra M, Aburto MR, Cop F, Llaó-Cid C, Härtl R, Damm M, Bethani I, Parrilla M, Husainie D, Schänzer A, Schlierbach H, Acker T, Mohr L, Torres-Masjoan L, Ritter M, Acker-Palmer A. (2018) Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system. Science;361(6404):eaao2861. link

Stefani J, Tschesnokowa O, Parrilla M, Robaye B, Boeynaems JM, Acker-Palmer A, Zimmermann H, Gampe K. (2018) Disruption of the Microglial ADP Receptor P2Y13 Enhances Adult Hippocampal Neurogenesis. Front Cell Neurosci.; 12:134. link

Dopeso H, Jiao HK, Cuesta AM, Henze AT, Jurida L, Kracht M, Acker-Palmer A, Garvalov BK, Acker T. (2018) PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFα. Cancer Res; 78(7):1805-1819. link

2017

Pfennig S, Foss F, Bissen D, Harde E, Treeck J, Segarra M and Acker-Palmer A. (2017) GRIP1 binds to ApoER2 and ephrinB2 to induce activity-dependent AMPA receptor insertion at the synapse. Cell Reports 21: 84-96. link

2016

Depner C, zum Buttel H, Garvalov BK, Cuesta AM, Bogurcu N, Aburto MR, Finkelmeier F, Kaulich K, Barbus S, Reifenberger R, Acker T and Acker-Palmer A. (2016) EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance. Nature Communications, 7:12329. link

2015

De Rossi P, Harde E, Dupuis J, Martin L, Chounlamountri N, Bardin M, Watrin C, Benetollo C, Pernet-Gallay K, Luhmann H, Honnorat J, Malleret G, Groc L, Acker-Palmer A, Salin P-A, Meissirel C (2015) A critical role for VEGF and VEGFR2 in NMDA receptor synaptic function and fear-related behavior. Molecular Psychiatry, 12:1768-1780. link

Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon SO, Segarra M, Eberhart CG, Acker-Palmer A, Tosato G. (2015) EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nature Communications 6: 6576. link

2014

Henze A-T, Garvalov BK, Seidel S, Cuesta A, Ritter M, Filatova A, Foss F, Dopeso H, Essmann CL, Maxwell PH, Reifenberger G, Carmeliet P, Acker-Palmer A and Acker T (2014). Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. Nature Communications.5:5582. link

Garvalov BK, Foss F, Henze, AT, Bethani I, Gräf-Höchst S, Singh D, Filatova A, Dopeso H, Seidel S, Damm M, Acker-Palmer A and Acker T (2014). PHD3 regulates EGFR internalization and signaling in tumours. Nature Communications 5: 5577. link

Seiradake E, Del Toro D, Nagel D, Cop F, Härtl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R. (2014). FLRT Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development. Neuron 22; 84: 370-385. link

Geiger JC, Lipka J, Segura I, Hoyer S, Schlager MA, Wulf PS, Weinges S, Demmers J, Hoogenraad CC and Acker-Palmer A (2014). The GRIP1/14-3-3 pathway coordinates cargo trafficking and dendrite development. Developmental Cell 28: 381-393. link

Worzfeld, T., Swiercz, J. M., Sentürk, A., Genz, B., Korostylev, A., Deng, S., Xia, J., Hoshino, M., Epstein, J. A., Chan, A. M., Vollmar, B., Acker-Palmer, A., Kuner, R., & Offermanns, S. (2014). Genetic dissection of plexin signaling in vivo. Proceedings of the National Academy of Sciences of the United States of America, 111(6), 2194–2199. link

2011

Senturk A, Pfennig S, Weiss A, Burk K and Acker-Palmer A (2011). EphrinBs are essential components of the Reelin pathway to regulate neuronal migration. Nature 472: 356-360. erratum 478: 274. link

Deutsch, G. B., Zielonka, E. M., Coutandin, D., Weber, T. A., Schäfer, B., Hannewald, J., Luh, L. M., Durst, F. G., Ibrahim, M., Hoffmann, J., Niesen, F. H., Sentürk, A., Kunkel, H., Brutschy, B., Schleiff, E., Knapp, S., Acker-Palmer, A., Grez, M., McKeon, F., & Dötsch, V. (2011). DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer. Cell, 144(4), 566–576. link

Doeppner, T. R., Bretschneider, E., Doehring, M., Segura, I., Sentürk, A., Acker-Palmer, A., Hasan, M. R., Elali, A., Hermann, D. M., & Bähr, M. (2011). Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia. Acta Neuropathologica, 122(4), 429–442. link

2010

Sawamiphak S, Seidel S, Essmann CL, Wilkinson G, Pitulescu ME, Acker T and Acker-Palmer A (2010). EphrinB2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature 465: 487–491. link

Bethani I, Skånland SS, Dikic I and Acker-Palmer A (2010). Spatial organization of transmembrane receptor signaling. EMBO J, 29: 2677-2685. link

Sawamiphak S, Ritter M and Acker-Palmer, A. (2010). Preparation of retinal explant cultures to study ex vivo tip endothelial cell responses. Nature Protocols 5: 1659-1665. link