Jihoon Nah

E D U C A T I O N

Ph.D Department of Biological Sciences, Seoul National University (2013)

B.S Korea University (2005)

E X P E R I E N C E

Assistant Professor Department of Biochemistry, Chungbuk National University (2022-present)

Research Associate Professor Seoul National University (2021-2022)

Postdoctoral Fellow Cardiovascular Research Institute, Rutgers University (2016-2021)

Postdoctoral Fellow Department of Biological Sciences, Seoul National University (2013-2016)

R E S E A R C H    I N T E R E S T

Molecular machinery of autophagy from initiation to autophagosome–lysosome fusion

Identification of mitophagy receptors and mechanisms of mitochondrial quality control

Biochemical, cell-based, and in vivo analysis of autophagy in cardiovascular and neurodegenerative disease models

Regulation of cell death by autophagy

Mechanism-based drug discovery

S E L E C T E D   P U B L I C A T I O N S

Nah J, Sung EA, Zhai P, Maejima Y, Hu C, Ramos-Zepeda J, Ikeda S, Mizushima W, Sadoshima J* (2026), "Cardiomyocyte-specific deficiency of C/EBPβ aggravates pressure overload-induced heart failure", Cardiovasc Res. 122(4):527-538.

Baek S, Chang JW, Yoo SM, Choo J, Jung S, Nah J*, Jung YK* (2024), "TMEM9 activates Rab9-dependent alternative autophagy through interaction with Beclin1", Cell Mol Life Sci. 81(1):322.

Nah J, Shirakabe A, Zhai P, Mizushima W, Nakada Y, Saito T, Sung E, Hu C, Sadoshima J* (2022), "Ulk1-dependent alternative mitophagy plays a protective role during pressure overload in the heart", Cardiovasc Res. 118(12):2638-2651.

Nah J, Zhai P, Huang CY, Fernández ÁF, Mareedu S, Levine B, Sadoshima J* (2020), "Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury", J Clin Invest. 130(6):2978-2991.

Saito T, Nah J, Oka SI, Mukai R, Monden Y, Maejima Y, Ikeda Y, Sciarretta S, Liu T, Li H, Baljinnyam E, Fraidenraich D, Fritzky L, Zhai P, Ichinose S, Isobe M, Hsu CP, Kundu M, Sadoshima J* (2019), "An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia", J Clin Invest. 129(2):802-819.

Nah J, Pyo JO, Jung S, Yoo SM, Kam TI, Chang JW, Han J, An SS, Onodera T, Jung YK* (2013), "BECN1/Beclin1 is recruited into lipid rafts by prion to activate autophagy in response to amyloid beta 42", Autophagy 9(12):2009-2021.

Pyo JO†, Nah J†, Kim HJ, Lee HJ, Heo J, Lee H, Jung YK* (2008), "Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death", Autophagy 4(3):315-321.