Tumor microenvironment

Cancer-associated adipocytes

Does adipocytes affect the breast cancer cells? (Breast Cancer Research 2015)

Does breast cancer cells affect the behaviors of nearby adipocytes? (PLoS ONE 2017)

Spatial tumor growth

• Does the shapes of breast cancer mean sometheing? (PLoS ONE 2015)

• CASQ2, a gene associated with spatial tumor grwoth, promotes breast cancer progression and metastasis via microenvironment remodeling (Mol Oncol 2021)

Microenvironment remodelling in breast cancer progression and metastasis

• A microRNA that disappears in cancer tissue can shape the microenvironment in breast cancer. (Cancer Res, 2019)

• JAK2 mediates paclitaxel resistance via microenvironment remodeling (J Mol Med, 2021)

• CX3CR1-positive immune cells in pre-metastatic niche formation for TNBC liver metastasis. (Mol Cancer Res, 2023)

• Tumor lysate as a neoantigen source (Neoplasia, 2025)

'Normal' epithelial cells

What happens to the normal epithelial cells facing nearby tumor cells? (Sci Rep 2021)