Experience
Experience
Research Experience
Research Experience
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Bioinformatics Divison, National Institute of Biotechnology
Bioinformatics Divison, National Institute of Biotechnology
Research Assistant (April 2024 – Present)
Research Assistant (April 2024 – Present)
Principal Investigator: Mohammad Uzzal Hossain
Project: Investigation of highly deleterious non-synonymous polymorphisms on PTEN protein’s structure and function
Project: Investigation of highly deleterious non-synonymous polymorphisms on PTEN protein’s structure and function
Relevant Publications:
• Hossain, M. U., Sakib, M. N., Rahman, A.B.Z. N., et al. PTEN Mutation Landscape: Structural and Functional Drivers of Lung Cancer. bioRxiv (2024) https://doi.org/10.1101/2024.10.06.616856
• Hossain, M. U., Mehak, M. A., Hassan, SM. Sajid., Sakib, M. N. et al. Dissecting Breast Cancer Heterogeneity Through Transcriptomics Insights of Diverse Etiological Factors for Common Biomarker Discovery. bioRxiv (2024) https://doi.org/10.1101/2024.10.20.619262
Laboratory of Chromatin Organization in Immune Cell Development - International Medical Center for Medical Sciences, Kumamoto University
Laboratory of Chromatin Organization in Immune Cell Development - International Medical Center for Medical Sciences, Kumamoto University
Research Intern (February 2024 – March 2024)
Research Intern (February 2024 – March 2024)
Principal Investigator: Daisuke Kurotaki, Ph.D. (https://ircms.kumamoto-u.ac.jp/research/daisuke_kurotaki/)
Hi-C method for studying chromatin conformation in different immune cells:
Hi-C method for studying chromatin conformation in different immune cells:
Studied immune cells such as dendritic cells, lymphocytes in spleen cells and lymph node of mouse with special focus on Irf8 transcription factor expression. Analyzed immune cells induced using IL-12.
RNA-Seq analysis for expression data of genes in dendritic cells:
RNA-Seq analysis for expression data of genes in dendritic cells:
Worked with the RNA-seq data, analyzed and visualized obtained from mice using shell scripting.
Bio-resources Technology & Industrial Biotechnology Lab – Jahangirnagar University
Bio-resources Technology & Industrial Biotechnology Lab – Jahangirnagar University
Research Assistant (August 2022 – January 2024)
Research Assistant (August 2022 – January 2024)
Principal Investigator: Prof. Dr. Mohammad Shahedur Rahman
Relevant Publications:
Thahsin, N., Khan, K. I., Sakib, M. N. & Rahman, M. S. Unveiling Novel Hyperglycosylated Analog of Human Erythropoietin: A Comprehensive Computational Exploration. bioRxiv (2024) https://doi.org/10.1101/2024.10.07.617028
Projects:
Characterization of different bacterial strains:
Focusing on differential production of bacterial protease and alpha amylase in biofilm and submerged fermentation of Bacillus strains. Also studying the effect of different minerals on crude enzyme activity.
Hepatitis C in Bangladesh - Prevalence and Detection Using Molecular Approaches:
Hepatitis C in Bangladesh - Prevalence and Detection Using Molecular Approaches:
A comprehensive review study was to find the present state of HCV in Bangladesh. Also determined the country's true HCV prevalence rate as well as demonstrated a clearer picture of the existing genotypes.
Volunteer Experience
Volunteer Experience
I worked as the head and directed more than 200 volunteers from my university and 20 other institutes into 10 different teams to successfully organize the program. Got an immense response from the Biotechnology enthusiastic community of Bangladesh and nearly 1100 students from 30 universities as well as over 100 secondary educational institutes from all over the nation participated in the event.
This event was planned to disseminate the ideas of Biotechnology to young learners from schools, colleges and universities. My post program survey suggests that by organizing a event of this genre, I was able to make people generating a keen interest on Biotechnology which will help in the future to develop scientific minds with critical thinking ability. This ability can be further nourished and applied in solving complex issues of our developing countries to ultimately build a community with sustainability to meet the challenges of 21st century.
Receiving crest of convener from chairman of Dept. of Biotechnology & Genetic Engineering, Jahangirnagar University.
❖ Organized Programs:
➢ 1st National Biotechnology Olympiad 2022
➢ Article Writing Competitions for University students
➢ International Seminar on Biotechnology & MoU signing with Coppin State University, USA
➢ Biotech Sports Week & Freshers reception and farewell
➢ Communicating Science of Genome Editing: A Strategy Workshop
Receiving crest and certificate from chief advisor of the Biotech Club, Dr. Umme Salma Zohora (Professor, Dept. of Biotechnology & Genetic Engineering, Jahangirnagar University).
❖ Work responsibilities:
➢ Organizing cultural (Pohela Boishakh), Inter-batch football & cricket tournaments and Seminars.
➢ Maintaining current student database.
Bdbo is a part of International Biology Olympiad (IBO) and works as local organizer of the competition.
❖ Work responsibilities:
➢ Promoting Bdbo to the students of the local schools & colleges of Savar, Dhaka.
➢ Organizing the regional & final rounds of the Olympiad from 2019-2023.
➢ Making questions and taking examinations.
➢ Organizing Bio-Camp & other events related to the Olympiad.
BDBO National Round 2019 at BCSIR School & College
BDBO Regional Round 2019 at Sher-e-bangla Agricultural University, Dhaka ( 9 March, 2019)
Campus Ambassador, National Seminar on Biotechnology for Sustainable Development Goals
Campus Ambassador, National Seminar on Biotechnology for Sustainable Development Goals
Date: 16 October, 2022
Date: 16 October, 2022
Organized by: Department of Genetic Engineering and Biotechnology, Jagannath University
❖ Work responsibilities:
➢ Promoting the program to my university as the campus ambassador.
➢ Communicate with ambassadors of other universities in Bangladesh to successfully organize the program.
June, 2020 - June 2021
June, 2020 - June 2021
August,2019- Present
August,2019- Present
© Mohammad Nazmus Sakib 2024
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