Experience

East West University

Lecturer, Department of Genetic Engineering and Biotechnology (January 2026 – Present)

Courses:

• GEB 7103: Cell Biology

• GEB 7203: Animal Physiology

• CHE 7208: Chemistry for Biologists - II

Bioinformatics Division, National Institute of Biotechnology

Graduate Research Assistant (April 2024 – Present)

Principal Investigator: Mohammad Uzzal Hossain 

Projects: 

1) In-silico investigation of highly deleterious non-synonymous polymorphisms on PTEN protein’s structure and function

• Structural and functional impact prediction of retrieved PTEN nsSNPs and homology modelling (using linux, python and R)

• RMSD, RMSF, Rg, SASA analysis using Molecular Dynamics(MD) simulations

2) Epidemiology, Genomic Diversity, and Antimicrobial Resistance Dynamics of Extended-Spectrum Beta-Lactamase-producing Enterobacterales (ESBL-E) in Bangladesh

• Stool sample collection of 250 Diarrhoeal patients (age group: ≤ 5 years) from different regions of Bangladesh

• Detection, isolation and whole genome sequencing of ESBL and Carbapenem-resistant Enterobacteriaceae

3) Exploring the Genetic Basis of Diarrheal Disease in Gram-Negative Pathogens through Pangenome Analysis

• Isolation and biochemical identification of 31 unique strains of gram-negative bacteria, including NIB009, NIB012, NIB013, NIB020, NIB025, NIB018 from selective media for the first time in Bangladesh

• Conducting antibiotic susceptibility test, pangenome analysis and pathway annotation network analysis

4) Dissecting Breast Cancer Heterogeneity Through Transcriptomics Insights of Diverse Etiological Factors

• RNA-seq dataset analysis and identification of upregulated and downregulated genes in breast cancer

5)  APDeeM: A Machine Learning Strategy towards Effective Peptide Vaccine Candidates Identification against Viruses

• Dataset preparation using bioinformatics tools (based on python) and writing original draft of manuscript

Relevant Publications:

• Hossain, M. U., Suchi, M. A., Sanjida, Z., Rahman, A. B. Z. N., Sakib, M. N., et al. (2025). Linking Genomic Landscape to Disease Mechanism: Core Genetic Factors Underlying Pathogenesis and Antimicrobial Resistance in Diarrheal Pathogens. bioRxiv. https://doi.org/10.1101/2025.08.31.673274

• Hossain, M. U., Sakib, M. N., Rahman, A.B.Z. N., et al. (2024). Mapping PTEN Mutation Landscape: Structural and Functional Drivers of Lung Cancer. bioRxiv. https://doi.org/10.1101/2024.10.06.616856

• Hossain, M. U., Suchi, M. A., Sanjida, Z., Rahman, A. B. Z. N., Sakib, M. N., et al. (2025). Linking Genomic Landscape to Disease Mechanism: Core Genetic Factors Underlying Pathogenesis and Antimicrobial Resistance in Diarrheal Pathogens. bioRxiv. https://doi.org/10.1101/2025.08.31.673274

• Hossain, M. U., Alom, M. R., Hasan, S. S., Sakib, M. N., et al. (2025). APDeeM: A machine Learning strategy towards Effective Peptide Vaccine Candidates Identification against Different Types of Viruses. bioRxiv. https://doi.org/10.1101/2025.08.25.671769

• Hossain, M. U., Mehak, M. A., Hassan, SM. Sajid., Sakib, M. N., et al. (2024) Dissecting Breast Cancer Heterogeneity Through Transcriptomics Insights of Diverse Etiological Factors for Common Biomarker Discovery. bioRxiv. https://doi.org/10.1101/2024.10.20.619262 

Laboratory of Chromatin Organization in Immune Cell Development - International Medical Center for Medical Sciences, Kumamoto University 

Research Intern (February 2024 – March 2024)

Principal Investigator: Daisuke Kurotaki, Ph.D. (https://ircms.kumamoto-u.ac.jp/research/daisuke_kurotaki/)

Hi-C Analysis of Chromatin Conformation in Immune Cells
Applied the Hi-C technique to investigate three-dimensional chromatin organization in murine immune cells. The study focused on dendritic cells and lymphocytes isolated from mouse spleen and lymph nodes, with particular emphasis on the regulation of the Irf8 transcription factor. Immune cells were experimentally stimulated using IL-12 to examine changes in chromatin interactions associated with activation.

RNA-Seq Analysis of Gene Expression in Dendritic Cells
Performed computational analysis of RNA-seq datasets derived from mouse dendritic cells. Utilized shell scripting–based pipelines for data processing, analysis, and visualization to characterize gene expression patterns and immune-related regulatory signatures.

Biotech Club, Jahangirnagar University

Office Secretary, Executive Committee 2022-23 (January 2022 - May 2023) (View Certificate)

❖ Organized Programs:

➢ 1st National Biotechnology Olympiad 2022 

➢ Article Writing Competitions for University students

➢ International Seminar on Biotechnology & MoU signing with Coppin State University, USA

➢ Biotech Sports Week & Freshers reception and farewell

➢ Communicating Science of Genome Editing: A Strategy Workshop

Biotech Club, Jahangirnagar University

Executive Member, Executive Committee 2018 (July 2018 - April 2019) (View Certificate)

❖ Work responsibilities:

➢ Organizing cultural (Pohela Boishakh), Inter-batch football & cricket tournaments and Seminars.

➢ Maintaining current student database.

Bangladesh Biology Olympiad (Bdbo), Jahangirnagar Region

Academic Secretary (January 2021 - December 2021) [Enzyme ID: 202104004] (View Certificate)

Enzyme (September, 2018 - December 2020)

Bdbo is a part of International Biology Olympiad (IBO) and works as local organizer of the competition.

❖ Work responsibilities:

➢ Promoting Bdbo to the students of the local schools & colleges of Savar, Dhaka.

➢ Organizing the regional & final rounds of the Olympiad from 2019-2023.

➢ Making questions and taking examinations.

➢ Organizing Bio-Camp & other events related to the Olympiad.

Executive member, International Society for Computational Biology (ISCB) Regional Student Group - Bangladesh

June, 2020 - June 2021