There is a growing body of research that indicated exercise may alter neurotransmitter function and promote growth of the hippocampus, which is known to have a smaller volume in people with depression. Aerobic exercise improves memory and promotes hippocampal neurogenesis. In a pilot study done by Leavitt (2014), look at aerobic exercise and hippocampus growth. The intervention consisted of 30 minutes sessions 3 times a week for 3 months. The measurements were taken through high-resolution MRI, fMRI, and memory assessments. It resulted that aerobic exercise increased 16.5% hippocampal volume and increased 53.7% in memory.
Another study by Szabo (2011), associates aerobic exercise with improvement of memory and hippocampus volume. The study conducted assessments of BMI, physical activity, hippocampal volume, spatial working memory, and frequency of forgetting. The findings indicate that older adults with higher levels of physical activity have a greater hippocampus volume. By having a greater hippocampus volume, they have more accurate and spatial memory and fewer episodes of forgetting.