PI

Changhan Lee Ph.D.

Education:

2007 - 2012  Ph.D., Dept. of Biological Sciences, KAIST, Korea

Advisor: Chankyu Park, Ph.D.


2003 - 2007  B.S., Dept. of Biological Sciences, KAIST, Korea


Research experience:

2021 –  present: Assistant professor, Dept. of Biological Sciences, Ajou University, Korea


2017 –  2020: Postdoctoral fellow

Dept. of Molecular Cellular and Developmental Biology, Howard Hughes Medical Institute (HHMI), 

University of Michigan, Ann Arbor, MI, USA

Advisor: James Bardwell, Ph.D.


2015: Visiting scholar

Center for Molecular Biology of the University of Heidelberg (ZMBH) and German Cancer Research Center (DKFZ), Heidelberg University, Germany 

Advisor: Axel Mogk, Ph.D. and Dr. Bernd Bukau Ph.D.


2013 –  2017: Postdoctoral fellow

Dept. of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden 

Advisor: Ute Römling, Ph.D.


2012 - 2013: Postdoctoral fellow

Dept. of Biological Sciences, KAIST, Daejeon, Korea

Advisor: Chankyu Park, Ph.D.


Activities:

2021 - present: 한국미생물학회 정회원

2021 - present: Korean Journal of Microbiology, Editor

2022 - present: 한국미생물학회 미생물 생리/생화학 분과 간사

2023 - present: 한국미생물 생명공학회 정회원

2024 - present: 한국미생물학회 정책기획위원회 실무위원

Changhan earned his Ph.D. degree at Korea Advanced Institute of Science and Technology (KAIST) in 2012. During his Ph.D. thesis, he characterized the regulatory mechanism to respond reactive electrophilic species (RES) in Escherichia coli under the supervision of Dr. Chankyu Park. In 2013, he moved to Ute Römling lab at Karolinska Institute in Sweden as a postdoc and expended his research area to protein quality control system in a key opportunistic human pathogen Pseudomonas aeruginosa. Changhan joined James Bardwell lab at University of Michigan, Howard Hughes Medical Institute (HHMI) in 2017 and studied kept his deep interest to protein folding and proteostasis in bacteria. He is amazed by the sophisticated protein quality contol system, called chaperones, in living orgasnisms, and continues his journey in science. Changhan peruses to understand how bacteria respond to various proteotoxic stresses and how it can be applied to understand host-microbe interaction and to develop new antimicrobial drug. He loves to travel around the world and watch movies.