Publications
2024
1. Sohn, J.#, Kwon, S.#, Lee, G.Y.#, Kim, S.S., Lee, Y., Lee, J., Jung, Y., Ham, S., Park, H.E.H., Park, S., Ha, S.G., Lee, D., and Lee, S.J.V.* HLH-30/TFEB mediates sexual dimorphism in immunity in Caenorhabditis elegans. Autophagy doi:10.1080/15548627.2024.2375779 (#co-first authors)
2.Molière, A., Park, J.Y.C., Goyala, A., Vayndorf, E.M., Zhang, B., Hsiung, K.C., Jung, Y., Kwon S., Statzer, C., Meyer, D., Nguyen, R., Chadwick, J., Thompson, M.A., Schumacher, B., Lee, S.J.V., Essmann, C.L., MacArthur, M.R., Kaeberlein, M., David, D., Gems, D., and Ewald, C.Y.* (2024) Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age. Geroscience doi: 10.1007/s11357-024-01232-x
3. Lee, G.Y., Ham S, and Lee, S.J.V.*. (2024) Brief guide to RNA sequencing analysis for nonexperts in bioinformatics. Mol. Cells. doi:10.1016/j.mocell.2024.100060 (Mini resource)
4. Lee, G.Y.#, Ham, S.#, Sohn, J., Kwon, H.C., and Lee, S.J.V.* (2024) Meta-analysis of the transcriptome identifies aberrant RNA processing as common feature of aging in multiple species. Mol. Cells doi:10.1016/j.mocell.2024.100047 (#co-first authors)
5. Ham, S., Kim, S.S., Park, S. Kwon, H.C., Ha, S.G., Bae, Y., Lee, G.Y., and Lee, S.J.V.* (2024) Combinatorial transcriptomic and genetic dissection of insulin/IGF-1 signaling-regulated longevity in Caenorhabditis elegans. Aging Cell, e14151. https://doi.org/10.1111/acel.14151.
6. Han, S. K.*, Kwon, H. C., Yang, J. S., Kim, S.*, and Lee, S.J.V.* (2024) OASIS portable: User-friendly offline suite for secure survival analysis. Mol. Cells doi.org/10.1016/j.mocell.2024.100011 (*corresponding authors)
2023
1. Kwon, H.C.#, Bae, Y.#, and Lee, S.J.V.* (2023) The role of mRNA quality control in the aging of Caenorhabditis elegans Mol. Cells doi.org/10.14348/molcells.2023.0103 (Invited review)
2. Lee, H., and Lee, S.J.V.* (2023) Ant-agonizing aging without tradeoffs in queens Mol. Cells doi: 10.14348/molcells.2023.0069 (Journal club)
3. Kim, E.#, Annibal, A.#, Lee, Y.#, Park, H.E.H.#, Ham, S.#, Jeong, D.E., Kim, Y., Park, S., Kwon, S., Jung, Y., Park, J., Kim S.S., Antebi, A.*, and Lee, S.J.V.* (2023) Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response. Nature Comm. 10.1038/s41467-023-39393-6
4. Ha, S.G., and Lee, S.J.V.* (2023) The role of tRNA-derived small RNAs in aging. BMB Reports 56(2):49-55 (Invited review)
2022
1. Ham, S.#, Kim, S.S.#, Park, S., Kim, E.J.E., Kwon, S., Park, H.E.H., Jung, Y., and Lee, S.J.V.* (2022) Systematic transcriptome analysis associated with physiological and chronological aging in Caenorhabditis elegans. Genome Res. 32(11-12):2003-2014 (#co-first authors)
2. Kim, S.S.#, Sohn J.#, and Lee, S.J.V.* (2022) Immunosenescence in Caenorhabditis elegans. Immunity & Ageing 19(1):56 (Invited review, #co-first authors)
3. Lee, H., and Lee, S.J.V.* (2022) Recent Progress in Regulation of Aging by Insulin/IGF-1 Signaling in Caenorhabditis elegans. Mol. Cells 45(11):763-770 (Invited review)
4. Kang, M.#, Kharbash, R.#, Byun, JM.#, Jeon, J.#, Ali, A.A., Ku, D., Yoon, J., Ku, Y., Sohn, J., Lee, S.J.V., Shin, D-Y., Koh, Y., Yoon, S-S., Hong, J.*, Kim, Y.* (2022) Double-stranded RNA induction as a potential dynamic biomarker for DNA-demethylating agents. Molecular Therapy – Nucleic Acids doi: 10.1016/j.omtn.2022.07.014 (#co-first authors, *corresponding authors)
5. Artan, M., Sohn, J., Lee, C.*, Park, S.Y.*, and Lee, S.J.V.* (2022) MON-2, a Golgi protein, promotes longevity by upregulating autophagy through mediating inter-organelle communications. Autophagy doi: 10.1080/15548627.2022.2039523 (Invited commentary, *corresponding authors)
2021
1. Jung, Y.#, Artan, M.#, Kim, N.#, Yeom, J.#, Hwang, A.B., Jeong, D.E., Altintas, O., Seo, K., Seo, M., Lee, D., Hwang, W., Lee, Y., Sohn, J., Kim, E.J.E., Ju, S., Han, S.K., Nam, H.J., Adams, L., Ryu, Y., Moon, D.J., Kang, C., Yoo, J.Y., Park, S.K., Ha, C.M., Hansen, M., Kim, S., Lee, C.*, Park, S.Y.*, and Lee, S.J.V.* (2021) MON-2, a Golgi protein, mediates autophagy-dependent longevity in Caenorhabditis elegans. Sci. Adv. doi: 10.1126/sciadv.abj8156 (#co-first authors, *corresponding authors)
2. Park, H.E.H.#, Hwang, W.#, Ham, S.#, Kim., E.#, Altintas, O., Park, S., Son, H.G., Lee, Y., Lee, D., Heo, W.D., and Lee, S.J.V.* (2021) A PTEN variant uncouples longevity from impaired fitness in Caenorhabditis elegans with reduced insulin/IGF-1 signaling. Nature Comm. doi: 10.1038/s41467-021-25920-w (#co-first authors)
3. Park, S., Sohn, J., Kwon, S., Kim, E.J.E., Jung, Y., Park, H.E.H., Kim, S.S., and Lee, S.J.V.* (2021) Age-dependent upregulation of Y RNAs in Caenorhabditis elegans. microPublication Biology doi: 10.17912/micropub.biology.000452
4. Lee, G.Y., and Lee, S.J.V.* (2021) Eyeless worms can run away from dangerous blues. Mol. Cells doi: 10.14348/molcells.2021.0201. (Journal club)
5. Shin, G., Koo, H.J., Seo, M., Lee, S.J.V.*, Nam, H.G.*, Jung, G.Y.* (2021) Transfer RNA-derived fragments in aging Caenorhabditis elegans originate from abundant homologous gene copies. Sci. Rep. doi: 10.1038/s41598-021-91724-z (*corresponding authors)
6. Lee, G.Y.#, Sohn, J.#, and Lee, S.J.V.* (2021) Combinatorial approach using Caenorhabditis elegans and mammalian systems for aging research. Mol. Cells doi: 10.14348/molcells.2021.0080. (Invited review, #co-first authors)
7. Kim, E.*, Kim, Y.K., and Lee, S.J.V.* (2021) Emerging functions of circular RNA in aging. Trends in Genetics doi.org/10.1016/j.tig.2021.04.014 (Review, *corresponding authors)
8. Lee, Y.#, Jung, Y.#, Jeong, D.E., Hwang, W., Ham, S., Park, H.E.H., Kwon, S., Ashraf, J.M., Murphy, C.T., and Lee, S.J.V.* (2021) Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. J Cell Biol. doi: 10.1083/jcb.202006174 (#co-first authors)
9. Park, S.#, Artan, A.#, Jeong, D.E., Park, H.E.H., Son, H.G., Kim, S.S., Jung, Y., Choi, Y., Lee, J.I., Kim., K., and Lee, S.J.V.* (2021) Diacetyl odor shortens longevity conferred by food deprivation in C. elegans via downregulation of DAF-16/FOXO. Aging Cell doi:10.1111/acel.13300 (#co-first authors)
2020
1. Lee, J.#, Kim, S.S.#, and Lee, S.J.V.* (2020) A mutation that alters the 255th glutamate to lysine in RSKS-1/S6 kinase reliably extends the lifespan of C. elegans. microPublication Biology. 10.17912/micropub.biology.000322 (#co-first authors)
2. Kim, E.J.E., Son, H.G., Park, H.E.H., Jung, Y., Kwon, S., and Lee, S.J.V.* (2020) Caenorhabditis elegans algn-2 is critical for longevity conferred by enhanced nonsense-mediated mRNA decay. iScience doi.org/10.1016/j.isci.2020.101713
3. Ham, S.*, and Lee, S.J.V.* (2020) Advances in transcriptomic analysis of human brain aging. Exp. Mol. Med. doi.org/10.1038/s12276-020-00522-6 (Review, *corresponding authors)
4. Kim, B.#, Lee, J.#, Kim, Y.#, and Lee, S.J.V.* (2020) Regulatory systems that mediate the effects of temperature on the lifespan of Caenorhabditis elegans. J Neurogen. doi.org/10.1080/01677063.2020.1781849 (Invited review, #co-first authors)
5. Park, S.#, Artan, A.#, Han, S.H.#, Park, H.E.H., Jung, Y., Hwang, A.B., Shin, W.S., Kim, K.T.*, and Lee, S.J.V.* (2020) VRK-1 Extends Lifespan by Activation of AMPK via Phosphorylation. Sci. Adv. 6 : eaaw7824 (#co-first authors, *corresponding authors)
6. Jung, Y.#, Kwon, S.#, Ham S.#, Lee, D., Park, H.E.H., Yamaoka, Y., Jeong, D.E., Artan, M., Altintas, O., Park, S., Hwang, W., Lee, Y., Son, H.G., An, S.W.A., Kim, E.J.E., Seo, M., and Lee, S.J.V.* (2020) C. elegans Lipin 1 moderates the lifespan-shortening effects of dietary glucose by maintaining ω-6 polyunsaturated fatty acids. Aging Cell 19(6):e13150 (#co-first authors)
7. Jeong, D.E.#, Lee, Y.#, Ham S.#, Lee, D., Kwon, S., Park, H.E.H., Hwang, S.Y., Yoo, J.Y., Roh, T.Y., and Lee, S.J.V.* (2020) Inhibition of the oligosaccharyl transferase in Caenorhabditis elegans that compromises ER proteostasis suppresses p38-dependent protection against pathogenic bacteria. PLoS Gen. 16(3):e1008617 (#co-first authors)
2019
1. Shomer, N., Kadhim, A.Z., Grants, J.M., Cheng, X., Alhusari, D., Bhanshali, F., Poon, A.F.Y., Lee, M.Y.Y., Muhuri, A., Park, J.I., Shih, J., Lee, D., Lee, S.J.V., Lynn, F.C., Taubert, S. (2019) Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans. PLoS Gen. 15(12):e1008508
2. Kim, E.J.E., and Lee, S.J.V.* (2019) Recent progresses on anti-aging compounds and their targets in Caenorhabditis elegans Transl. Med. Aging 3:121-124 (Invited perspective)
3. Lee, D.#, An, S.W.A.#, Jung Y.#, Yamaoka, Y., Ryu, Y., Goh, G.Y.S., Beigi, A., Yang, J.S., Jung, G.Y., Ma, D., Ha, C.M., Taubert, S., Lee, Y., and Lee, S.J.V.* (2019) MDT-15/MED15 permits longevity at low temperature via enhancing lipidostasis and proteostasis PLoS Biol. 17(8):e3000415 (#co-first authors)
4. Kim S.S., and Lee, S.J.V.* (2019) Non-coding RNAs in Caenorhabditis elegans aging Mol. Cells 42(5):379-385 (Invited review)
5. An, S.W.A.#, Choi, E.S.#,Hwang, W., Son, H.G., Yang, J.S., Seo, K., Nam, H.J., Nguyen, N.T.H., Kim, E.J.E., Suh, B.K., Kim, Y., Nakano, S., Ryu, Y., Ha, C.M., Mori, I., Park., S.K., Yoo, J.Y., Kim, S., and Lee, S.J.V.* (2019) KIN-4/MAST kinase promotes PTEN-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain. Aging Cell 18(3):e12906 (#co-first authors)
6. Son, H.G., Altintas, O., Kim, E.J.E., Kwon, S., and Lee, S.J.V.* (2019) Age-dependent changes and biomarkers of aging in Caenorhabditis elegans. Aging Cell 18(2):e12853 (Review)
2018
1. Son, H.G.#, Seo, K.#, Seo, M., Park, S., Ham, S., An, S.W.A., Choi, E.S., Lee, Y., Baek, H., Kim, E., Ryu, Y., Ha, C.M., Hsu, A.L., Roh, T.Y., Jang, S.K., and Lee, S.J.V.* (2018) Prefoldin 6 mediates longevity response from heat shock factor 1 to FOXO in C. elegans. Genes Dev. 32:1562-1575 (#co-first authors)
2. Xu, C.*#, Hwang, W.#, Jeong, D.E., Ryu, Y., Ha, C.M., Lee, S.J.V. Liu, L., and He, Z.M. (2018) Genetic inhibition of an ATP synthase subunit extends lifespan in C. elegans. Sci. Rep. 8(1):14836 (#co-first authors)
3. Kim, E., Kim, J.H., Seo, K., Hong, K.Y., An, S.W.A., Kwon, J., Lee, S.J.V., and Jang, S.K. (2018) eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B. Cell. Mol. Life Sci. 75(23):4287-4300
4. Lee, Y., Lee, S.J.V.* and Min, K.J.* (2018) Meeting report: Asian Society for Aging Research Symposium 2018 Trans. Med. Aging 2:11-14 (Invited review, *corresponding authors)
5. Kwon, S.#, Kim, E.J.E.#, and Lee, S.J.V.* (2018) Mitochondria-mediated defense mechanisms against pathogens in Caenorhabditis elegans. BMB Reports 51(6):274-279 (Invited review, #co-first authors)
6. Jeong, D.E., Lee, Y., and Lee, S.J.V.* (2018) Western blot analysis of C. elegans proteins. In Hypoxia. Methods in Molecular Biology, (Ed: Huang) 1742:213-225 Humana Press, New York, NY (Book chapter)
2017
1. Park, S., Park, H.E.H., Son, H.G. and Lee, S.J.V.* (2017) The role of RNA helicases in aging and lifespan regulation Trans. Med. Aging 1:24-31 (Invited review)
2. Na, J., Shin, G.W., Son,H.G., Lee, S.J.V.* and Jung, G.Y.* (2017) Multiplex quantitative analysis of microRNA expression via exponential isothermal amplification and conformation-sensitive DNA separation Sci. Rep. (*corresponding authors) 7(1):11396
3. Park, S., Jung, Y., An, S.W.A., Son, H.G., Hwang, W., Lee, D., Artan, M., Park, H.E.H., Jeong, D.E., Lee, Y., Lee, S.J.V.* (2017) RNAi targeting Caenorhabditis elegans α-arrestins has small or no effects on lifespan F1000 Res. 6:1515
4. Jung, H.Y., Lee, D., Ryu, H.G., Choi, B.H., Go, Y., Lee, N., Lee, D., Son, H.G., Jeon, J., Kim, S.H., Yoon, J.H., Park, S.M., Lee, S.J.V., Lee, I.K., Choi, K.Y., Ryu, S.H., Nohara, K., Yoo, S.H., Chen, Z., Kim, K.T. (2017) Myricetin improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1α. Sci. Rep. 7(1):6237
5. Jeong, D.E.#, Lee, D.#, Hwang, S.Y., Lee, Y., Lee, J.E., Seo, M., Hwang, W., Seo, K., Hwang, A.B., Artan, M., Son, H.G., Jo, J.H., Baek, H., Oh, Y.M., Ryu, Y., Kim, H.J., Ha, C.M., Yoo, J.Y.*, and Lee, S.J.V.* (2017) Mitochondrial chaperone HSP-60 regulates antibacterial immunity via p38 MAP kinase signaling. EMBO J. 36(8):1046-1065 (#co-first authors, *corresponding authors)
6. Son, H.G., and Lee, S.J.V.* (2017) Longevity regulation by NMD-mediated RNA quality control. BMB reports 50(4):160-161 (Invited perspective)
7. Son, H.G.#, Seo, M.#, Ham, S., Hwang, W., Seo, K., An,S.W.A., Artan, M., Kaletsky, R.L., Arey, R.N., Ryu, Y., Ha, C.M., Kim,Y.K., Murphy, C.T., Roh, T.Y., Nam, H.G.*, and Lee, S.J.V.* (2017) RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans. Nature Comm. 8:14749 (#co-first authors, *corresponding authors)
8. Park, H.E.#, Jung, Y.#, and Lee, S.J.V.* (2017) Survival assays using Caenorhabditis elegans. Mol. Cells 40(2):90-99 (Review) (#co-first authors)
9. Lee, D., Son, H.G., Jung, Y., and Lee, S.J.V.* (2017) The role of dietary carbohydrates in organismal aging. Cell. Mol. Life Sci. 74(10):1793-1803 (Invited review)
10. An, S.W.A.#, Artan, M.#, Altintas, O.#, Park, S.#, and Lee, S.J.V.* (2017) "Longevity regulation by insulin/IGF-1 signalling”, Chapter 4 in Ageing: Lessons from C. elegans, Healthy Ageing and Longevity (Ed: Olsen & Gill), 63-81, Springer (#co-first authors)
2016
1. Artan, M., An, S.W.A., and Lee, S.J.V.* (2016) Heat FLiPs a hormonal switch for longevity. Dev. Cell 39(2):133–134 (Preview)
2. Jung, J.Y., Lim, J.H., Kim, S.Y., Im, D.K., Seok, J.Y., Lee, S.J.V. and Jung, G.Y. (2016) Precise precursor rebalancing for isoprenoids production by fine control of gapA expression in Escherichia coli. Metab. Eng. 38:401-408
3. Han, S.K., Lee, D., Lee, H, Kim, D., Son, H.G., Yang, J.S., Lee, S.J.V.* and Kim, S.* (2016) OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research Oncotarget (*corresponding authors) 7(35):56147-56152
4. Seo, M., Park, S., Nam, H.G.*, and Lee, S.J.V.* (2016) RNA helicase SACY-1 is required for the longevity caused by various genetic perturbations in Caenorhabditis elegans. Cell Cycle (*corresponding authors) 15(14):1821-1819 (Peer-Reviewed Invited Extra View Article)
5. Lee, Y.#, Hwang, W.#, Jeong, J.Y., Park, S., Cabatbat, J.J.T., Kim, P.J., and Lee, S.J.V.* (2016) Inverse correlation between longevity and developmental rate among wild C. elegans strains. Aging (Albany NY) (#co-first authors) 8(5):986-9996.
6. Artan, M., Jeong, D.E., Lee, D., Kim, Y.I., Son, H.G., Husain, Z., Kim, J., Altintas, O., Kim, K., Alcedo, J., and Lee, S.J.V.* (2016) Food-derived sensory cues modulate longevity via distinct neuroendocrine insulin-like peptides. Genes Dev. 30:1047-1057 (Cover article, highlighted article)
7. Altintas, O.#, Park, S.#, and Lee, S.J.V.* (2016) The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster. BMB Rep. 49(2):81-92 (Invited review) (#co-first authors)
2015
1. Lee, D.#, Jeong, D.E.#, Son, H.G., Yamaoka, Y., Kim, H., Seo, K., Khan, A.A., Roh, T.Y., Moon, D.W., Lee, Y., and Lee, S.J.V.* (2015) SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat. Genes Dev. 29:2490-2503 (#co-first authors)
2. Hahm, J.H., Kim, S., DiLoreto, R., Shi, C., Lee, S.J.V., Murphy, C.T., and Nam, H.G. (2015) C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation. Nature Comm. Nov 20;6:8919. doi: 10.1038/ncomms9919
3. Hwang, W., Artan, M., Seo, M., Lee, D., Nam, H.G., and Lee, S.J.V.* (2015) Inhibition of elongin C promotes longevity and protein homeostasis via HIF-1 in C. elegans. Aging Cell 14:995-1002
4. Lee, Y.#, An, S.W.A.#, Artan, M.#, Seo, M.#, Hwang, A.B.#, Jeong, D.E.#, Son, H.G.#, Hwang, W.#, Lee, D.#,Seo, K.#, Altintas, O., Park, S., and Lee, S.J.V.* (2015) “Genes and pathways that influence the longevity of Caenorhabditis elegans”, Chapter 8 in Aging Mechanisms: Longevity, Metabolism, and Brain Aging (Ed: Mori & Mook-Jung), 123-169, Springer, Japan (#co-first authors)
5. Seo, M., Seo, K., Hwang, W., Koo, H.J., Hahm, J.H., Yang, J.S., Han, S.K., Hwang, D., Kim, S., Jang, S.K., Lee, Y., Nam, H.G.*, and Lee, S.J.V.* (2015) RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in C. elegans. Proc. Natl. Acad. Sci. USA 112(31):E4246-E4255 (direct submission, PNAS Plus article) (*corresponding authors)
6. Artan, M.#, Hwang, A.B.#, Lee, S.J.V.*, and Nam, H.G.* (2015) Meeting Report: Symposium on the Genetics of Aging and Life History II. Aging (Albany NY) 7:362-369 (Review, #co-first authors, *corresponding authors)
7. Kwon, N., Hwang, A.B., You, Y.J., Lee, S.J.V.*, and Je, J.H.* (2015) Dissection of C. elegans behavioral genetics in 3D environments. Sci. Rep. 5,9564 (*corresponding authors)
8. Lee, D.#, Hwang, W.#, Artan, M.#, Jeong, D.E.#, and Lee, S.J.* (2015) Effects of nutritional components on aging. Aging Cell (Review) 14:8-16 (#co-first authors)
2014
1. Hwang, A.B., Ryu, E.A., Artan, M., Chang, H.W., Kabir, M.H., Nam, H.J., Lee, D., Yang, J.S., Kim, S., Mair, W.B., Lee, C., Lee, S.S., and Lee, S.J.* (2014) Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in C. elegans. Proc. Natl. Acad. Sci. USA 111:E4458-E4467 (Direct submission, PNAS Plus article)
2. Lee, S.H., An, H.S., Jung, Y.W., Lee, E.J., Lee, H.Y., Choi, E.S., An, S.W., Son, H., Lee, S.J., Kim, J.B., and Min, K.J. (2013) Korean mistletoe (Viscum album coloratum) extract extends the lifespan of nematodes and fruit flies. Biogerontology 15(2):153-164
2013
1. Shin, G.W., Na, J., Seo, M., Chung, B., Nam, H.G., Lee, S.J.*, and Jung, G.Y.* (2013) Precise Expression Profiling by Stuffer-Free Multiplex Ligation-Dependent Probe Amplification. Anal. Chem. 85(19):9383-9389. (*corresponding authors)
2. Seo, K., Choi, E., Lee, D., Jeong, D.E., Jang, S.K.*, and Lee. S.J.* (2013) Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF-1 signaling pathways in C. elegans. Aging Cell 12(6):1073-1081 (*corresponding authors)
3. Kwon, N., Pyo, J.Y., Lee. S.J.*, and Je, J.H.* (2013) 3-D Worm Tracker for Freely Moving C. elegans. PLoS One 8(2):e57484 (*corresponding authors)
4. Zhang, P., Judy, M., Lee, S.J., and Kenyon, C. (2013) Direct and Indirect Gene Regulation by a Life-Extending FOXO Protein in C. elegans: Roles for GATA Factors and Lipid Gene Regulators. Cell Metab. 17(1):85-100
2012
1. Gaglia, M.M.#, Jeong, D.E.#, Ryu, E.A.#, Lee, D. , Kenyon, C.*, and Lee, S.J.* (2012) Genes that act downstream of sensory neurons to influence longevity, dauer formation and pathogen responses in Caenorhabditis elegans. PLoS Genetics 8(12):e1003133 (#co-first authors, *corresponding authors)
2. Jeong, D.E.#, Artan, M.#, Seo, K., and Lee, S.J.* (2012) Regulation of lifespan by chemosensory and thermosensory systems: findings in invertebrates and their implications in mammalian aging. Front. Genet. 3:218 (Invited review, #co-first authors)
3. Lee, J.S., Park A.H., Lee, S.H., Lee, S.H., Kim, J.H., Yang, S.J., Yeom, Y.I., Kwak, T.H., Lee, D., Lee, S.J. , Lee, C.H., Kim, J.M., and Kim, D. (2012) Beta-lapachone, a modulator of NAD metabolism, prevents health declines in aged mice. PLoS One 7(10):e47122
4. Hwang, A.B.#, Jeong, D.E.#, and Lee, S.J.* (2012) Mitochondria and organismal longevity. Curr. Genomics 13(7):519-532 (Invited review, #co-first authors)
2011
1. Yang, J.S., Nam, H.J., Seo, M. , Han, S.K., Choi, Y., Nam, H.G., Lee, S.J.*, and Kim, S.* (2011) OASIS: online application for the survival analysis of lifespan assays performed in aging research. PLoS One 6(8):e23525 (*corresponding authors)
2. Hwang, A.B., and Lee, S.J.* (2011) Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection. Aging (Albany NY) 3:304-310 (Invited review)
2010
1. Lee, S.J.*#, Hwang, A.B.#, and Kenyon, C.* (2010) Inhibition of respiration extends C. elegans’ life span via reactive oxygen species that increase HIF-1 activity. Curr. Biol. 20:2131-2136 (#co-first authors, *corresponding authors)
2. Yamawaki, T., Berman, J., McCormick, M., Gaglia, M.M., Lee, S.J., and Kenyon, C. (2010) The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling. PLoS Biol. 8:e1000468
3. Henis-Korenblit, S., Zhang, P., Hansen, M., McCormick, M., Lee, S.J. , Cary, M., and Kenyon, C. (2010) Insuling/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity. Proc. Natl. Acad. Sci. USA 107:9730-9735
4. Kim, Y.I. , Ryu, T., Lee, J., Heo, Y.S., Ahnn, J., Lee, S.J., and Yoo, O. (2010) A genetic screen for modifiers of Drosophila caspase Dcp-1 reveals caspase involvement in autophagy and novel caspase-related genes. BMC Cell Biol. 11:9
2009
1. Lee, S.J., Murphy, C.T., and Kenyon, C. (2009) Glucose shortens the lifespan of Caenorhabditis elegans by down-regulating DAF-16/FOXO activity and aquaporin gene expression. Cell Metab. 10:379-391
2. Lee, S.J., and Kenyon, C. (2009) Regulation of longevity response to temperature by thermosensory neurons in Caenorhabditis elegans. Curr. Biol. 19:715-722
Before 2009
2007
- Murphy, C.T.#, Lee S.J.#, and Kenyon C. (2007) Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 104:19046-19050 (#co-first authors)
- Hansen, M., Taubert, S., Crawford, D., Libina, N., Lee, S.J., and Kenyon, C. (2007). Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6:95-110.
2004
- Lee, S.J., and Montell, C. (2004). Suppression of constant-light-induced blindness but not retinal degeneration by inhibition of the rhodopsin degradation pathway. Curr. Biol. 14:2076-2085
- Lee, S.J., Xu, H., and Montell, C. (2004). Rhodopsin kinase activity modulates the amplitude of the visual response in Drosophila. Proc. Natl. Acad. Sci. USA 101:11874-11879 (Direct submission)
- Lee, S.J., and Montell, C. (2004). Light-dependent translocation of visual arrestin regulated by the NINAC myosin III. Neuron 43:95-103.
- Xu, H., Lee, S.J. , Suzuki, E., Dugan, K.D., Stoddard, A., Li, H.S., Chodosh, L.A., and Montell, C. (2004). A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. EMBO J. 23:811-822.
2003
- Lee, S.J., Xu, H., Kang, L., Amzel, L.M., and Montell, C. (2003). Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin. Neuron 39:121-132.
2001
- Lee, S.J., and Montell, C. (2001). Regulation of the rhodopsin protein phosphatase, RDGC, through interaction with calmodulin. Neuron 32:1097-1106.