Rapid changes in serum sodium can result in damage to the central nervous system. This is typically manifested by central pontine myelinolysis.
Extapontine myelinolysis may be found concurrently with (~15%) or in the absence of (~20%) pontine disease
On imaging their is increased T2/FLAIR in the central pons, sparing the corticospinal tracts
Extrapontine myelinolysis manifests increased T2/FLAIR signal in the Basal ganglia, thalami, external and extreme capsules, cerebral cortex, and middle cerebellar peduncles