Publications and Presentations

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2021|2020|2019|2018|2017|2016|2015|2014|2013|Presentations

Publications

2021

15. Mahajan M.,  Bharambe N., Shang Y., Lu B., Mandal A., Madan Mohan P., Wang R., Boatz J. C., Galvez J. M. M., Shnyrova A. V., Qi X., Buck M., van der Wel P. C. A., and Ramachandran R. NMR identification of a conserved Drp1 cardiolipin-binding motif essential for stress-induced mitochondrial fission. Proceedings of the National Academy of Sciences, (2021), 118, 29, e2023079118.

2020

14. Navaratna T., Atangcho L., Mahajan M., Subramanian V., Case M., Min A., Tresnak D., Thurber G. M. Directed Evolution Using Stabilized Bacterial Peptide Display. Journal of American Chemical Society, (2020), 142, 4, 1882-1894.

2019

13. Mahajan M., Ravula T., Prade E., Anantharamaiah G. M. and Ramamoorthy A. Probing membrane enhanced protein-protein interactions in the minimal redox complex of Cytochrome-P450 and P450-reductase. Chemical Communications, (2019), 55, 5777-5780. 

12. Lu B., Mahajan M*., Mandal A., Bharambe N., Wang R., Boatz C. J., Van der Wel P., Buck M., Qi X., and Ramachandran R. Structural and Mechanistic Bases of Drp1-Cardiolipin Interactions in Mitochondrial Fission. Biophysical Journal (2018) 116 (3), 454a-455a (* Co-first author)

2018

11. Mahajan M., Chatterjee D., Bhuvaneswari K., Pillay S., Bhattacharjya S. NMR structure and localization of a large fragment of the SARS-CoV fusion protein: Implications in viral cell fusion. BBA-Biomembranes (2018), 1860 (2), 407-415.

10. Mahajan M., Prade E., Im S.C., Zhang M., Gentry K., Anantharamaiah G. M., Waskell L. and Ramamoorthy A. High Resolution Functional Interaction of a Minimal Cyp450-Redox Complex in Lipid Bilayer. Protein Science (2018) 27, 161-162.

9. Prade E., Mahajan M.*, Im S.C., Zhang M., Gentry K., Anantharamaiah G. M., Waskell L. and Ramamoorthy A. A Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs. Angewandte Chemie (2018), 57  (28), 8458-8462. (* Co-first author)

8. Sumangala N., Mahajan M., Ravula T. and Ramamoorthy A. Cytochrome-P450’s spin state influences its binding affinity to its redox partners. Biophysical Journal (2018) 114 (3), 425a.

2017

7. Ravula T., Barnaba C., Mahajan M., Anantharamiah G.M., Im S.C., Waskell L., Ramamoorthy A. Membrane environment drives cytochrome P450's spin transition and its interaction with cytochrome b 5. Chem. Comm. (2017),  53 (95), 12798-12801.

6. Gentry K., Prade E., Barnaba C., Zhang M., Mahajan M., Im S.C., Anantharamaiah G. M., Nagao S., Waskell L. and Ramamoorthy A. Kinetic and Structural Characterization of the Effects of Membrane on the Complex of Cytochrome b 5 and Cytochrome c. Scientific reports (2017), 7 (1), 7793.

5. Kumar A., Mahajan M., Awasthi B., Tandon A., Harioudh M., Shree S., Singh P., Shukla P., Ramachandran R., Mitra K., Bhattacharjya S. and Ghosh J. K. Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities. Scientific Reports (2017), 7 (39925).

2016

4. D’Souza A. Mahajan M. and Bhattacharjya S. Designed multi-stranded heme binding β-sheet peptides in membrane. Chemical science (2016), 7 (4), 2563-2571.

2015

3. Mahajan M. and Bhattacharjya S. NMR structures and localization of the potential fusion peptides and the pre-transmembrane region of SARS-CoV: Implications in membrane fusion. BBA-Biomembranes (2015), 1848 (2), 721-730.

2014

2. Mahajan M. and Bhattacharjya S. Designed di‐heme binding helical transmembrane protein. ChemBioChem (2014), 15 (9), 1257-1262.

2013

1. Mahajan M. and Bhattacharjya S. β‐Hairpin Peptides: Heme Binding, Catalysis, and Structure in Detergent Micelles. Angewandte Chemie (2013), 125 (25), 6558-6562.

Conference/ Symposium Presentations

Posters

8. Directed Evolution Using Stabilized Bacterial Peptide Display. 61st Experimental NMR conference (ENC), Baltimore, Maryland USA March 2020.

7. High Resolution Functional Interaction of a Minimal CYP450-Redox Complex in Lipid Bilayer. 32nd Annual Symposium of The Protein Society, Boston, USA, June 2018.

6. Cytochrome-P450's Spin State Influences its Binding Affinity to its Redox Partner. 62nd Annual Meeting of The Biophysical Society, San Francisco, California, USA, Feb 2018.

5. High resolution probing of the role of the membrane on the CPR-CYP2B4 interacting interface and electron transfer pathways. Great Lakes Drug Metabolism and Drug Disposition Symposium at Western Michigan University, Kalamazoo, Michigan, USA, May 2017.

4. NMR Structural Studies of Membrane Active Peptides and Proteins. Great Lakes Regional NMR Symposium at CWRU, Cleveland, USA, September 2015.

3. Designing of Heme Binding Transmembrane Protein using an Amphiphilic Antimicrobial Peptide. Euromar 2014, ETH-Zürich, Switzerland, July 2014.

2. Peptide Engineering Towards an Evolution of Synthetic Membrane Proteins. 5th Annual KoRS-CB Retreat. Konstanz, Germany, August 2013.

1. Artificial membrane proteins with catalase activity. 2nd International Workshop – Natural and Artificial Photosynthesis, Bioenergetics and Sustainability, Singapore, June 2012.

Invited & short Talks

7. Biomolecular Characterization using Biophysics and NMR. (invited talk) at College of Pharmacy, University of Kentucky, USA, March 2021.


6. Understanding principles of membrane proteins folding using designed peptides. (invited Video talk) at G. B. Pant Institute of Engineering and Technology, India, September 2020.

5. Structure-based Functional Characterization of Membrane active Peptides and Proteins. Oral Presentation delivered at Harvard Medical School, Boston, USA, May 2019.

4. Biophysical characterization of Neuropilin1 (Nrp1) towards the understanding of signal transduction.  (talk) Departmental retreat at Department of Physiology and Biophysics, CWRU, Cleveland, USA, September 2016.

3. Understanding Membrane Proteins using Synthetic Model Peptides. (invited talk) Reaxys Prize Club Symposium, Singapore, October 2014.

2. Designing of functional membrane proteins: A study using Model Peptides. (invited talk) Max Planck Institute of Biophysical Chemistry, Germany, June 2014.

1. Designing of functional membrane proteins (short talk)  20th International AUC Conference, University of Texas Health Science Center at San Antonio, USA, March 2012.