Lim Lab

Exploring how 14-3-3 proteins contribute to metabolism and metabolic diseases

Welcome to the Lim lab at the Centre de recherche du Centre hospitalier de l'Université de Montréal!

We are a group of motivated scientists, whose goal is to understand how adaptor/scaffold proteins belonging to the 14-3-3 protein family control metabolic processes and whether they contribute to the development of chronic diseases, such as diabetes and obesity.

Lab news!

(Click to expand each year to see the great news!)


  • December: Siyi was awarded a PhD award from the CIRTN-R2FIC CREATE Training Program!

  • December: Huge congrats to Fred for passing his pre-doc (comprehensive) exam. The second PhD candidate of the Lim lab!

  • November: Calgary, Alberta- Siyi He presented her work at the inaugural Canadian Islet Research Training Network (CIRTN) meeting and Diabetes Canada Professional Conference

  • Siyi's first paper from the Lim lab!! This nicely foreshadows a new direction for the lab!! =)

  • September: Stockholm, Sweden: Both Fred Abou Azar (Oral) and Siyi He (Short oral) presented their work at the EASD meeting.

  • August: Huge congrats to Siyi for passing her pre-doc (comprehensive) exam. She is the first PhD candidate of the Lim lab!

  • June: Congrats to Siyi who was awarded doctoral awards from the FRQNT and the FRQS! Way to go!

  • June: Congrats to postdoc, Dr. Sabri Rial, who presented a poster at the American Diabetes Association Scientific Sessions in New Orleans

  • May: Welcome Albert Tannous (supported by a NSERC USRA) George Vorincu (supported by a Bourse première, UdeM) to the lab for a research stage!

  • May: Welcome back to Samanta Del Veliz (UNCUYO) who is joining us for another research stay. This time she is supported by a Company of Biologists Traveling Fellowship.

  • April: Awesome, our JCI Insight paper made the cover!!

  • March: Congrats to former fellow, Dr. Yves Mugabo, on his paper getting accepted at JCI Insight!


September: We had to say good-bye to Dr. Yves Mugabo, Ph.D., the first member of the Lim lab! Congrats and best of luck Yves!

September: Congratualtions to Fred Abou Azar for his first (and many more to come) paper published in Front. Cell. Dev. Biol.

March: Welcome to Frédéric Paré, who joins the lab as a research technician.


December: Congratulations to Siyi He for being awarded a Bourse de merité by the Université de Montréal!!

October: WOO HOO! Gareth was awarded the Prix Jeune chercheur Jean-Davignon 2021 du Réseau CMDO

September: Welcome to Siyi He, M.Sc., a new Ph.D. student in the lab!

July: Congratulations to Kadidia Diallo, M.Sc. for her recently accepted paper in Molecular Metabolism!

April: Hooray! Work from Abel Oppong, a previous M.Sc. student, was accepted for publication in Am J Physiol Endo Metab.

April: Congratulations to Dr. Sabri Rial for his FRQNT Postdoctoral Fellowship award!

March: The lab was awarded a CIHR Bridge grant to study the role of 14-3-3zeta in pancreatic beta-cell function

February: Welcome the newest postdoctoral fellow to the Lim lab, Dr. Sabri Rial.

January: The Lim lab was awarded an Intercentre Initiative by the CMDO to further our collaboration with Dr. André Carpentier's group to study the role of 14-3-3zeta in thermogenesis!


December 2019: Abel Oppongs's memoire was official accepted! Congratulations on successfully completing your Master's (M.Sc.) degree, Abel!

November 2019: Kadidia Diallo's memoire was official accepted! Congratulations on completion a successful Master's (M.Sc.) degree, Kadidia!

October 2019: The Lim lab was successful in obtaining an Islet Award Initiative grant from the Intergrated Islet Distribution Program (IIDP) to further support its efforts to understand how 14-3-3 proteins can influence pancreatic beta-cell function.

September 2019: After the first Interstellar Initiative Workshop, the lab was awarded funding from AMED to support a collaborative project with Drs Shuhei Nakamura (Osaka University) and Mark McCormick (University of New Mexico)!

September 2019: Welcome Fred Azar, B.Sc., to the lab as a new M.Sc. student.

July 2019: Woohoo! The lab's application for the Interstellar Initiative, which is co-organized by the New York Academy of Sciences (NYAS) and the Japan Agency for Medical Research (AMED) was accepted!

May 2019: Congratulations to Dr. Yves Mugabo, a postdoc in the lab. He has the recipient of both a CIHR Postdoctoral award and a Banting Postdocotoral award. Way to go!

May 2019: Welcome to Maria Galipeau and David Millette for their stagiaires. They come from the Biochemistry program at the University of Montreal

April 2019: Please welcome Samanta Del Veliz, who joins us as a visiting student from Universidad Nacional de Cuyo. She is being supported by a Wood Whelan Fellowship from the IUBMB!

April 2019: Congratulations and best wishes to Samantha Yuen, who just completed her Co-op work-term. A very talented and capable student from Concordia University!


November 2018: New invited review discussing the therapeutical potential of targeting 14-3-3 proteins for metabolic diseases is out in Pharmacological Research! Congrats to Abel and Kadidia!

October 2018: Congrats to Abel on being awarded a travel award from the Montreal Diabetes Research Centre

October 2018: Members of the Lim lab had a successful trip to Halifax for the Diabetes Canada Annual meeting!

September 2018: Congrats to Yves for his review being accepted in Endocrinology!

July 2018: Welcome to Christina Grech, who joins us for a summer internship. She is currently a medical student in Austria and is part of the IFMSA programme!

June 2018: Congratulations to Gareth, who was awarded the CIHR Canada Research Chair in Adipocyte Development!

May 2018: Congrats to Gareth, who received a Fonds de recherce Québec Santé (FRQS) Chercheur boursier-Junior 1 Scholar Award

April 2018: Congrats to Abel for his CIHR Canada Graduates Scholarship-Master's (CGS-M) Award

March 2018: Congrats to Yves for his first paper from the Lim Lab, which is now online in the Journal of Biological Chemistry

February 2018: The Lim Lab was awarded a John Evan's Leaders Fund (JELF) award from the Canada Foundation for Innovation (CFI) to establish an Adipocyte Profiling Platform!


September 2017: Welcome Dr. Yves Mugabo, Ph.D., who is the Lim Lab's first postdoctoral fellow!

September 2017: Welcome M.Sc. Students: Kadidia Diallo, Abel Oppong, and Jeremie Shabani to the Lim Lab!

June 2017: The Lim Lab has been awarded a Discovery Award from the Banting Research Foundation!

May 2017: The Lim Lab welcomes Mina Sadeghi (Hons Biology & Pharmacology Co-op) from McMaster University as its first co-op student

April 2017: The Lim Lab was awarded its first CIHR (Project) grant to study the role of 14-3-3zeta in adipocytes!

March 2017: The Lim lab was awarded an NSERC Discovery grant to understand how 14-3-3zeta may anchor transcriptional complexes during adipocyte differentiation


Sept 2016: The Lim lab was born!