The rapid pace and dire impacts of climate change urgently require powerful short-term mitigation strategies. We propose to slow global warming by removing methane from the atmosphere at significant scale using methanotrophic bacteria.
This project involves 13C-based metabolic flux analysis of a type I methanotroph, Methylotuvimicrobium buryatense 5GB1C, and investigation of its metabolic adaptation to varied environments or genetic manipulation.
An optimized one-carbon assimilation pathway via enzyme engineering (formolase)
Conversion of natural gas to fuels using methanotrophic bacteria
Systems level insights into alternative methane cycling modes in Lake Washington
Engineering metabolic pathways for conversion of CO2 to fuels
Methylotrophic metabolism in Methylobacterium extorquens AM1
Coupling function to genomics in microbial communities via single-cell analysis (DOE)