Indications for baseline BMD

2010 Osteoporosis Guidelines

All women and men age ≥ 65 years

Menopausal women & men aged 50-64 years with clinical risk factors for fracture:

• Fragility fracture after age 40
• Prolonged glucocorticoid use (≥3 months in prior year at a prednisone equivalent ≥7.5 mg daily)
• Other high-risk medication use (AI, ADT)
• Parental hip fracture
• Vertebral fracture or osteopenia identified on X-ray
• Current smoking or High alcohol intake
• Low body weight (< 60 kg) or major weight loss (>10% of weight at age 25 years)
• Rheumatoid arthritis
• Other disorders strongly associated with osteoporosis such as:
  • Primary hyperparathyroidism, T1DM, osteogenesis imperfecta, uncontrolled hyperthyroidism, hypogonadism or premature menopause (< 45 years), Cushing’s disease, chronic malnutrition or malabsorption, chronic liver disease, COPD and chronic inflammatory conditions (e.g., inflammatory bowel disease)

Younger Adults (age < 50 years)

• Fragility fracture
• Prolonged use of glucocorticoids
• Use of other high-risk medications
• Hypogonadism or premature menopause
• Malabsorption syndrome
• Primary hyperparathyroidism
• Other disorders strongly associated with rapid bone loss and/or fracture