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LATTE
Featured Publication

Thalamostriatal circuit as a therapeutic target of alcohol use disorder 

  • Authors: Hyein Song, Jongseo Lee, Jiyong Lee, Jin Kim, Jinho Kim, Shinwoo Kang, Jeongseop Kim (Corresponding) 

  • Journal: Neurobiology of Disease 

  • Publication date: June  2026

  • Jornal Imfact Factor: 6.0 (JCR Rank, Molecular Biology: 51/330)

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Featured Publication

Amygdala-hippocampus circuit regulates stress coping via mGluR5-dependent BDNF signaling

  • Authors: Tae-Eun Kim (First), Tae-Yong Choi, Ja Wook Koo, and Jeongseop Kim (Corresponding)

  • Journal: Molecules and Cells

  • Publication date: March  2026

  • Jornal Imfact Factor: 8.2 (JCR Rank, Molecular Biology: 39/328)

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Featured Publication

Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD

  • Authors: Jeongseop Kim

  • Journal: Frontiers in Immunology

  • Publication date: 11 November  2025

  • Jornal Imfact Factor: 5.9 (JCR Rank, Immunology: 34/183)

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Featured Publication

mGluR5 as a Potential Orchestrator of Astrocyte Interactions in Neurological Disorders

  • Authors: Jeongseop Kim, Jiyong Lee, Hyein Song, Ja Wook Koo, Shinwoo Kang 

  • Journal: Neural Plasticity

  • Publication date: 09 September  2025

  • Jornal Imfact Factor: 3.7 (JCR Rank, Neurosciences: 100/317)

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Featured Publication

ECoGScope: An integrated platform for real-time Electrophysiology and fluorescence imaging 

  • Authors: Jonghee Eun, Jeongseop Kim (First), Tae-Eun Kim, Ja Wook Koo, Namsun Chou 

  • Journal: Biosensors and Bioelectronics 

  • Publication date: 15 April  2024

  • Jornal Imfact Factor: 12.6 (JCR Rank, Chemistry, analytical: 2/111, 상위: 1.35%)

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Featured Publication

Transcutaneous auricular vagus nerve stimulation in anesthetized mice induces antidepressant effects by activating dopaminergic neurons in the ventral tegmental area 

  • Authors: Tae-Yong Choi, Jeongseop Kim (First), Ja Wook Koo

  • Journal: Molecular Brain 

  • Publication date: 27 November  2024

  • Jornal Imfact Factor: 3.3 (JCR Rank, Neurosciences, analytical: 124/314)

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Featured Publication

Distinct prefrontal projection activity and transcriptional state conversely orchestrate social competition and hierarchy

  • Authors: Tae-Yong Choi, Hyoungseok Jeon, Sejin Jeong, Eum Ji Kim, Jeongseop Kim, Yun Ha Jeong, Byungsoo Kang, Murim Choi, Ja Wook Koo 

  • Journal: Neuron

  • Publication date: 21 February  2024

  • Jornal Imfact Factor: 15.3 (JCR Rank, Neurosciences, analytical: 7/314, 상위: 2.1%)

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Featured Publication

Synaptotagmin-4 induces anhedonic responses to chronic stress via BDNF signaling in the medial prefrontal cortex  

  • Authors: Jeongseop Kim, Sihwan Seol, Tae-Eun Kim, Joonhee Lee, Ja Wook Koo, Hyo Jung Kang 

  • Journal: Experimental & Molecular Medicine 

  • Publication date: 01 February  2024

  • Jornal Imfact Factor: 17.5 (JCR Rank, Medicine, Research & Experimental: 4/191, 상위: 1.8%)

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Featured Publication

Lactobacillus reuteri ATG-F4 alleviates chronic stress-induced anhedonia by modulating the prefrontal serotonergic system

  • Authors: Jiyun Lee, Eum-Ji Kim, Gun-Seok Park, Jeongseop Kim, Tae-Eun Kim, Yoo Jin Lee, Juyi Park, Jihee Kang, Ja Wook Koo, Tae-Yong Choi 

  • Journal: Experimental neurobiology 

  • Publication date: 31 October  2023

  • Jornal Imfact Factor: 2.4 (JCR Rank, Medicine, Research & Experimental: 117/195)

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Featured Publication

The role of glutamate underlying treatment-resistant depression 

  • Authors: Jeongseop Kim, Tae-Eun Kim, Seung-Hwan Lee, Ja Wook Koo 

  • Journal: Clinical Psychopharmacology and Neuroscience 

  • Publication date: 31 August  2023

  • Jornal Imfact Factor: 3.2 (JCR Rank, Medicine, Pharmacology & Pharmacy: 164/352)

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Featured Publication

Metabotropic glutamate receptor 5 in amygdala target neurons regulates susceptibility to chronic social stress 

  • Authors: Jeongseop Kim, Shinwoo Kang, Tae-Yong Choi, Keun-A Chang, Ja Wook Koo 

  • Journal: Biological Psychiatry 

  • Publication date: 15 July  2022

  • Jornal Imfact Factor: 13.382 (JCR Rank, Psychiatry: 6/279, 상위: 2%)

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Featured Publication

Transcutaneous auricular vagus nerve stimulation in anesthetized mice induces antidepressant effects by activating dopaminergic neurons in the ventral tegmental area 

  • Authors: Joo Han Lee, Efrain A Ribeiro, Jeongseop Kim, Bumjin Ko, Hope Kronman, Yun Ha Jeong, Jong Kyoung Kim, Patricia H Janak, Eric J Nestler, Ja Wook Koo, Joung-Hun Kim 

  • Journal: Biological Psychiatry 

  • Publication date: 15 November  2020

  • Jornal Imfact Factor: 13.382 (JCR Rank, Psychiatry: 6/279, 상위: 2%)

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Featured Publication

Dysregulation of mood by chronic unpredictable stress induce impairment of episodic memory 

  • Authors: Jeongseop Kim, Joonhee Lee, Tae-Eun Kim, Hyo Jung Kang, Ja Wook Koo 

  • Journal: IBRO Reports  

  • Publication date: 01 September  2019

Contact us

Tel: 053-650-3615

Email: jeongseop@cu.ac.kr 

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About us

The Lab of Affective Trait & Translational Epigenetics (LATTE) investigates fundamental brain mechanisms using mouse models. We employ genetics, optogenetics, chemogenetics, circuit tracing, electrophysiology, histology, and in vivo imaging to study how genes, neurons, and glial cells shape brain function. 

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