Publications

 Seattle University (undergraduate co-workers are underlined)

30. Chan, J.K.; Parasurama, S.; Atlas, R.; Xu, R.; Jongeblood, U.A. Alexander, B.; Langenhan, J.M.; Thorton, J.A.; Riffell, J.A. Science 2024, 383, 607-611. "Olfaction in the anthropocene: NO3 negatively affects floral scent and nocturnal pollination."

29. Rykaczewski, K.A.; Sabourin, K.E.; Goo, P.J.; Griggs, L.H.; Jain, S.; Reed, P.A.M.; Langenhan, J.M. Carbohydr. Res. 2020, 493, 108022. “Generation of a glycosylated asparagine residue through chemoselective acylation of a glycosylhydrazide.”

28. Ferrenberg, S.; Langenhan, J.M.; Loskot, S.A.; Rozal, L.M.; Mitton, J.B. Ecosphere 2017, 8, e01975. “Resin monoterpene defenses decline within three widespread species of pine (Pinus) along a 1530-m elevational gradient.”

27. Langenhan, J.M.; McLaughlin, R.P.; Loskot, S.A.; Rozal, L.M.; Clay, M.S.; Alaimo, P.J. J. Carbohydr. Res. 2016. http://www.tandfonline.com/doi/abs/10.1080/07328303.2016.1139122?journalCode=lcar20

26.  Ferrenberg, S.; Kane, J.M.; Langenhan, J.M. Tree Physiol. 2015, 35, 107-111. “To grow or defend? Pine seedlings grow less but induce more defences when a keyresource is limited.”

25.  Alaimo, P.J.; Langenhan, J.M.; Suydam, I.T. J. Chem. Educ. 2014, 91, 2093-2098. “Aligning the Undergraduate Organic Laboratory Experience with Professional Work: TheCentrality of Reliable and Meaningful Data.”

·         Editorial highlight in Science 2014, 346, 962.

24.  Loskot, S.A.; Zhang, J.; Langenhan, J.M. J. Org. Chem 2013, 78, 12189-12193. “Nucleophilic Catalysis of MeON-Neoglycoside Formation by Aniline Derivatives.”

23.  Langenhan, J.M.; Mullarky, E.; Rogalsky, D.K.; Rohlfing, J.R.; Tjaden, A.E.; Werner, H.M.; Rozal, L.M. ; Loskot, S.A. J. Org. Chem. 2013, 78, 1670-1676. "Amphimedosides A-C:Synthesis, Chemoselective Glycosylation, and Biological Evaluation."

22.  Langenhan, J.M.; Endo, M.M.; Engle, J.M.; Fukumoto, L.L.; Rogalsky, D.K.; Slevin, L.K.; Fay, L.R.; Lucker, R.W.; Rohlfing, J.R.; Smith, K.R.; Tjaden, A.E.; Werner, H.M. Carbohydr. Res. 2011, 346, 2663-2676.  “Synthesisand Biological Evaluation of RON-Neoglycosidesas Tumor Cytotoxins.”

21.  Iyer, A.; Zhou, M.; Azad, N.; Elbaz, H.; Wang, L.; Rogalsky, D.K.; Rojanasakul, Y.; O’Doherty, G.A.; Langenhan, J.M. ACS Med. Chem. Lett. 2010, 1, 326-330.  “A DirectComparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides.”

20.  Alaimo, P.J.; Marshall, A.-L.; Andrews, D.M.; Langenhan, J.M. Org. Synth. 2010, 87, 192-200.  “1,3,5-Triacetylbenzene.”

19.  Langenhan, J.M.; Alaimo, P.J.; Tanner, M.J.; Ferrenberg, S.M., J. Chem. Educ., 2010, 87, 856-861. “Safety teams: An Approach to Engage Students inLaboratory Safety.”

·         Chemical & Engineering News blog feature: http://cenblog.org/the-safety-zone/2010/07/undergrad-laboratory-safety-teams/ (7/7/2010)

·         Editorial highlight in J. Chem. Educ. 2010, 87, 764-765

18.  Alaimo, P.J.; Bean, J.C.; Langenhan, J.M.; Nichols, L.  Writing Across the Curriculum Journal, 2009, 20, 17-32. “Eliminating Lab Reports: A Rhetorical Approach for Teaching the Scientific Paper in Sophomore Organic Chemistry.”

·         Podcast highlight in Science: http://www.sciencemag.org/content/332/6032/919/suppl/D

17.  Langenhan, J.M.; Engle, J.M.; Slevin, L.K.; Fay, L.R.; Lucker, R.W.; Smith, K.R.; Endo, M.M. Bioorg. Med. Chem. Lett. 2008, 18, 670-673.  “Modifying the Glycosidic Linkage inDigitoxin Analogs Provides Selective Cytotoxins.”

Prior to Seattle University Appointment

16. Griffith, B.R.; Langenhan, J.M.; Thorson, J.S. Curr. Opin. Biotechnol. 2005, 16, 622-630.  “‘Sweetening’ Natural Products via Glycorandomization.”

15. Langenhan, J.M.; Griffith, B.R.; Thorson, J.S. J. Nat. Prod. 2005, 68, 1696-1711. “Neoglycorandomization and Chemoenzymatic Glycorandomization: Two Complementary Tools for Natural Product Diversification.”

14. Langenhan, J.M.; Peters, N.R.; Guzei, I.A.; Hoffman, F.M.; Thorson, J.S. Proc. Natl. Acad. Sci. 2005, 102, 12305-12310. “Enhancing the Anti-Cancer Properties of Cardiac Glycosides via Neoglycorandomization.”

·         Chemical & Engineering News feature:

http://pubs.acs.org/cen/news/83/i33/8333notw1.html  (8/15/2005)

13. Langenhan, J.M.; Thorson, J.S. Curr. Org. Synth. 2005, 2, 59-81. “Recent carbohydrate-based chemoselective ligation applications.”

12. Fu, X.; Langenhan, J.M.; Thorson, J.S. Disc. Med. 2004, 4, 111-114. “Combinatorial chemoenzymatic strategies for in vitro glycorandomization: efforts toward antibiotic optimization.”

11. Langenhan, J.M.; Gellman, S.H.  Org. Lett., 2004, 6, 937-940.  “Effects of alternative side chain pairings and reverse turn sequences on antiparallel sheet structure in β-peptide hairpins.”

10. Guzei, I.L., Langenhan, J.M.  Acta. Cryst., 2003, C59, i95-i96.  “The correct space group of NaPF6•H2O.”

9.   Langenhan, J.M.; Gellman, S.H.  J. Org. Chem. 2003, 68, 6440-6443.  “Preparation of protected syn-α,β-dialkyl β-amino acids that contain polar side chain functionality.”

8.   Langenhan, J.M.; Christianson, L.A.; Guzei, I.A.; Gellman, S.H.  Angew. Chem. Int. Ed., 2003, 42, 2402-2405.  “Parallel sheet structure in β-peptides.”

7.   Schinnerl, M.; Murray, J.K.; Langenhan, J.M.; Gellman, S.H.  Eur. J. Org. Chem., 2003, 4, 721-726.  “Asymmetric synthesis of a new helix-forming β-amino acid: trans-4-aminopiperdine-3-carboxylic acid.”

6.   Guzei, I.L., Langenhan, J.M., Chung, Y.J. Acta. Cryst., 2002, E58, o65-o66.  “2S,3S-2-Benzyl-3-(nosylamino)butano-4-lactone.”

5.   Langenhan, J.M., Fisk, J.D., Gellman, S.H.  Org. Lett., 2001, 3, 2559-2562.  “Evaluation of hydrogen bonding complementarity between a secondary sulfonamide and an α-amino acid residue.”

4.   Romo, D.; Rzasa, R. M.; Schmitz, W. D.; Yang, J.; Cohn, S. T.; Buchler, I. P.; Shea, H. A.; Park, K.; Langenhan, J. M.; Messerchmidt, N. B.; Cox, M. M.  Total Synthesis of Marine Natural Products Driven by Novel Structure, Potent Biological Activity, and/or Synthetic Methodology.  In The Role of Natural Products in Drug Discovery;  Mulzer, J.; Bohlmann, R., Eds.; Ernst Schering Research Foundation Workshop 32; Springer-Verlag Publishers: Berlin, Germany, 2000; pp 103-148.

3.   Huck, B.R., Langenhan, J.M., Gellman, S.H.  Org. Lett., 1999, 1, 1717-1720.  “Non-hydrogen-bonded secondary structure in β-peptides: evidence from circular dichroism of (S)-pyrrolidine-3-carboxylic acid oligomers and (S)-nipecotic acid oligomers.”

2.   Paris, P.L., Langenhan, J.M., Kool, E.T.  Nucleic Acids Res., 1998, 26, 3789-3793.  “Probing DNA sequences in solution with a monomer-excimer fluorescence color change.”

1.   Romo, D., Rzasa, R.M., Shea, H.A., Park, P., Langenhan, J.M., Sun, L., Akhiezer, A., Lui, J.O.  J. Am. Chem. Soc., 1998, 120, 12237-12254.  “Total synthesis and immunosuppressive activity of (-)-pateamine A and related compounds: implementation of a β-lactam-based macrocyclization.”