学術論文
(*Corrresponding author, #Equal contribution )
Nakanishi T, Enomoto M, Igaki T*.
Iro-C/IRX creates anti-cancerized epithelial field against IL-6-dependent malignant tumorigenesis.
bioRxiv (2026) [preprint]
Bhargava P, Chen S, Lee J, Yoshinari Y, Nishimura T, Ushio M, Sugiura Y, Cheng KF, Fung YS, Hase K, Nakamura H, Enomoto M, Kim J, Johnson H, Liao Y, Hirano Y*.
Microbiome-host interactions drive a trade-off between sleep quality and lifespan in Drosophila.
bioRxiv (2025) [preprint]
Enomoto M*, Ohsawa S*.
Cancer progression through systemic signaling viewed from Drosophila.
Curr Opin Cell Biol, 95, 102545 (2025) [Pubmed]
Enomoto M*, Igaki T.
Cell-cell interactions that drive tumorigenesis in Drosophila.
Fly, 16 (1): 367-381 (2022) [Pubmed]
Enomoto M*, Takemoto D, Igaki T*.
Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila.
Dev Cell, 56, 2223-2236.e5 (2021) [Pubmed]
Enomoto M, Siow C, Igaki T*.
Drosophila as a cancer model.
Adv Exp Med Biol, 1076: 173-194 (2018) [Pubmed]
Enomoto M, Vaughen J, Igaki T*.
Non-autonomous overgrowth by oncogenic niche cells: cellular cooperation and competition in tumorigenesis.
Cancer Sci, 106 (12): 1651-1658 (2015)[Pubmed]
Enomoto M, Kizawa D, Ohsawa S, Igaki T*.
JNK signaling is converted from anti- to pro-tumor pathway by Ras-mediated switch of Warts activity.
Dev Biol, 403 (2): 162-171 (2015)[Pubmed]
Enomoto M, Igaki T*.
Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila.
EMBO Rep, 14 (1): 65-72 (2013)[Pubmed]
Ohsawa S, Sato Y, Enomoto M, Nakamura M, Betsumiya A, Igaki T*.
Mitochondrial defect drives non-autonomous tumour progression through Hippo signaling in Drosophila.
Nature, 490: 547-551 (2012)[Pubmed]
Inoko A, Matsuyama M, Goto H, Ohmuro-Matsuyama Y, Hayashi Y, Enomoto M, Ibi M, Urano T, Yonemura S, Kiyono T, Izawa I, Inagaki M*.
Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.
J Cell Biol, 197 (3): 391-405 (2012)[Pubmed]
Enomoto M, Igaki T*.
Deciphering tumor-suppressor signaling in flies: Genetic link between Scribble/Dlg/Lgl and the Hippo pathways.
J Genet Genom, 38 (10): 461-470 (2011)[Pubmed]
Ibi M, Zou P, Inoko A, Shiromizu T, Matsuyama M, Hayashi Y, Enomoto M, Mori D, Hirotsune S, Kiyono T, Tsukita S, Goto H, Inagaki M*.
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.
J Cell Sci, 124 (6): 857-864 (2011)[Pubmed]
Kasahara K, Goto H, Enomoto M, Tomono Y, Kiyono T, Inagaki M*.
14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage.
EMBO J, 29 (16): 2802-2812 (2010)[Pubmed]
Enomoto M, Goto H*, Tomono Y, Tsujimura K, Kiyono T, Inagaki M*.
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during the G2/M transition.
J Biol Chem, 284 (49): 34223-34230 (2009)[Pubmed]
Ikegami Y, Goto H, Kiyono T, Enomoto M, Kasahara K, Tomono Y, Tozawa K, Morita A, Kohri K, Inagaki M*.
Chk1 phosphorylation at Ser286 and Ser301 occurs with both stalled DNA replication and damage checkpoint stimulation.
Biochem Biophys Res Commun, 377 (4): 41227-41231 (2008)[Pubmed]
Okabe M, Enomoto M, Maeda H, Kuroki K, Ohtsuki K*.
Biological characterization of suramin as a selective inhibitor for the PKA-mediated phosphorylation of HBV core protein in vitro.
Biol Pharm Bull, 29 (9): 1810-1814 (2006)[Pubmed]
Enomoto M, Sawano Y, Kosuge S, Yamano Y, Kuroki K, Ohtsuki K*.
High phosphorylation of HBV core protein by two alpha-type CK2-activated cAMP-dependent protein kinases in vitro.
FEBS Lett, 580 (3): 894-899 (2006)[Pubmed]
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細胞競合と代償性増殖におけるJNKシグナルの役割
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細胞の協調と競合におけるHippo経路の役割
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がんの発生・進展を促すニッチ細胞
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