Publications

細胞サイズ

MMS21/HPY2 and SIZ1, two Arabidopsis SUMO E3 ligases, have distinct functions in development. Ishida T, Yoshimura M, Miura K, Sugimoto K, PLoS ONE, 2012;7(10):e46897. doi: 10.1371/journal.pone.0046897.

 

Developmental control of endocycles and cell growth in plants. Breuer C#, Ishida T#, Sugimoto K, Curr Opin Plant Biol, 2010 Dec;13(6):654-60. doi: 10.1016/j.pbi.2010.10.006. (#equal contribution) 

 

Auxin modulates the transition from the mitotic cycle to the endocycle in Arabidopsis. Ishida T, Adachi S, Yoshimura M, Shimizu K, Umeda M, Sugimoto, K. Development, 2010 Jan;137(1):63-71. doi: 10.1242/dev.035840.

 

SUMO E3 ligase HIGH PLOIDY 2 regulates endocycle onset and meristem maintenance in Arabidopsis. Ishida T, Fujiwara S, Miura K, Stacey N, Yoshimura M, Schneider K, Adachi S, Minamisawa K, Umeda M, Sugimoto K, Plant Cell, 2009 Aug;21(8):2284-97. doi: 10.1105/tpc.109.068072


（共同研究）

MYB3R-SCL28-SMR module with a role in cell size control negatively regulates G2 progression in Arabidopsis. Takatsuka H, Nomoto Y, Yamada K, Mineta K, Breur C, Ishida T, Yamagami A, Sugimoto K, Nakano T, Ito M, Plant Signal Behav, in press.


A hierarchical transcriptional network activates specific CDK inhibitors that regulate G2 to control cell size and number in Arabidopsis. Nomoto Y, Takatsuka H, Yamada K, Suzuki T, Suzuki T, Huang Y, Latrasse D, An J, Gombos M, Breuer C, Ishida T, Maeo K, Imamura M, Yamashino T, Sugimoto K, Magyar Z, Bögre L, Raynaud C, Benhamed M, Ito M, Nat Commun, 2022 Mar 29;13(1):1660. doi: 10.1038/s41467-022-29316-2.


Transcriptional repression by MYB3R proteins regulates plant organ growth. Kobayashi K, Suzuki T, Iwata E, Nakamichi N, Suzuki T, Chen P, Ohtani M, Ishida T, Hosoya H, Müller S, Leviczky T, Pettkó-Szandtner A, Darula Z, Iwamoto A, Nomoto M, Tada Y, Higashiyama T, Demura T, Doonan JH, Hauser MT, Sugimoto K, Umeda M, Magyar Z, Bögre L, Ito M, EMBO J, 2015 Aug 4;34(15):1992-2007. doi: 10.15252/embj.201490899.


Differential regulation of B2-type CDK accumulation in Arabidopsis roots. Okushima Y, Shimizu K, Ishida T, Sugimoto K, Umeda M, Plant Cell Rep, 2014 Jul;33(7):1033-40. doi: 10.1007/s00299-014-1581-z.


The ATM-dependent DNA damage response acts as an upstream trigger for compensation in the fas1 mutation during Arabidopsis leaf development. Hisanaga T, Ferjani A, Horiguchi G, Ishikawa N, Fujikura U, Kubo M, Demura T, Fukuda H, Ishida T, Sugimoto K, Tsukaya H. Plant Physiol, 2013 Jun;162(2):831-41. doi: 10.1104/pp.113.216796.


Jasmonate controls leaf growth by repressing cell proliferation and the onset of endoreduplication while maintaining a potential stand-by mode. Noir S, Bömer M, Takahashi N, Ishida T, Tjir-Li T, Balbi V, Shanahan H, Sugimoto K, Devoto A, Plant Physiol, 2013 Apr;161(4):1930-51. doi: 10.1104/pp.113.214908. 


Transcriptional repression of the APC/C activator CCS52A1 contributes to the active termination of cell growth. Breuer C, Morohashi K, Kawamura A, Takahashi N, Ishida T, Umeda M, Grotewold E, Sugimoto K, EMBO J, 2012 Dec 12;31(24):4488-501. doi: 10.1038/emboj.2012.294. 


Arabidopsis lonely guy (LOG) multiple mutants reveal a central role of the LOG-dependent pathway in cytokinin activation. Tokunaga H, Kojima M, Kuroha T, Ishida T, Sugimoto K, Kiba T, Sakakibara H, Plant J, 2012 Jan;69(2):355-65. doi: 10.1111/j.1365-313X.2011.04795.x.


Functional analyses of the Arabidopsis LONELY GUY family encoding cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis. Kuroha T, Tokunaga H, Kojima M, Umeda N, Ishida T, Nagawa S, Fukuda H, Sugimoto K, Sakakibara H, Plant Cell, 2009 Oct;21(10):3152-69. doi: 10.1105/tpc.109.068676


CRISPR-Cas9/ゲノム編集

A collection of mutants for CLE-peptide-encoding genes in Arabidopsis generated by CRISPR/Cas9 mediated gene targeting. Yamaguchi Y#, Ishida T #*, Yoshimura M, Imamura Y, Shimaoka C, Sawa S, Plant Cell Physiol., 2017 Nov 1;58(11):1848-1856. doi: 10.1093/pcp/pcx139 (#equal contribution; *corresponding author) 


Developing heritable mutations in Arabidopsis thaliana using a modified CRISPR/Cas9 toolkit comprising PAM-altered Cas9 variants and gRNAs. Yamamoto A, Ishida T*, Yoshimura M, Kimura Y, Sawa S, Plant Cell Physiol., 2019 Oct 1;60(10):2255-2262. doi: 10.1093/pcp/pcz118. (*corresponding author) 


（共同研究）

CLE3 and its homologs share overlapping functions in the modulation of lateral root formation through CLV1 and BAM1 in Arabidopsis thaliana. Nakagami S, Aoyama T, Sato Y, Kajiwara T, Ishida T, Sawa S, Plant J. 2023 Mar;113(6):1176-1191. doi: 10.1111/tpj.16103


Root-knot nematode modulates plant CLE3-CLV1 signaling as a long-distance signal for successful infection. Nakagami S, Notaguchi M, Kondo T, Okamoto S, Ida T, Sato Y, Higashiyama T, Tsai AY-L, Ishida T, Sawa S, Sci Adv. 2023 Jun 2;9(22):eadf4803. doi: 10.1126/sciadv.adf4803.


A group of CLE peptides regulates de novo shoot regeneration in Arabidopsis thaliana. Kang J, Wang X, Ishida T, Grienenberger E, Zheng Q, Wang J, Zhang Y, Chen W, Chen M, Song XF, Wu C, Hu Z, Jia L, Li C, Liu CM, Fletcher JC, Sawa S, Wang G, New Phytol, 2022 Jun 1. doi: 10.1111/nph.18291.


Long-distance translocation of CLAVATA3/ESR-related 2 peptide and its positive effect on root sucrose status. Okamoto S, Kawasaki A, Makino Y, Ishida T, Sawa S, Plant Physiol, 2022 May 14;kiac227. doi: 10.1093/plphys/kiac227.

 

CLE42 delays leaf senescence by antagonizing ethylene pathway in Arabidopsis. Zhang Y, Tan S, Gao Y, Kan C, Wang H, Yang Q, Xia X, Ishida T, Sawa S, Guo H, Li Z, New Phytol, 2022 Apr 9. doi: 10.1111/nph.18154.

 

Control of Root Stem Cell Differentiation and Lateral Root Emergence by CLE16/17 Peptides in Arabidopsis. Zhang L, Yang Y, Mu C, Liu M, Ishida T, Sawa S, Zhu Y, Pi L, Front Plant Sci, 2022 Apr 18;13:869888. doi: 10.3389/fpls.2022.869888.

  

CLE9 peptide-induced stomatal closure is mediated by abscisic acid, hydrogen peroxide, and nitric oxide in Arabidopsis thaliana. Zhang L, Shi X, Zhang Y, Wang J, Yang J, Ishida T, Jiang W, Han X, Kang J, Wang X, Pan L, Lv S, Cao B, Zhang Y, Wu J, Han H, Hu Z, Cui L, Sawa S, He J, Wang G, Plant Cell Environ., 2019 Mar;42(3):1033-1044. doi: 10.1111/pce.13475.

 

The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signaling. Shi C, von Wangenheim D, Herrmann U, Wildhagen M, Kulik I, Kopf A, Ishida T, Olsson V, Anker MK, Albert M, Butenko M, Felix G, Sawa S, Claassen M, Friml J, Aalen R, Nature Plants, 2018 Aug;4(8):596-604. doi: 10.1038/s41477-018-0212-z


有用化合物の探索・クマモナミド

Discovery, characterization and functional improvement of kumamonamide as a novel plant growth inhibitor that disturbs plant microtubules. Ishida T, Yoshimura H, Takekawa M, Higaki T, Ideue T, Hatano M, Igarashi M, Tani T, Sawa S, Ishikawa H,, Sci Rep, 2021 Mar 23;11(1):6077. doi: 10.1038/s41598-021-85501-1.


植物の微小管研究 (博士研究)

Helical microtubule arrays in a collection of twisting tubulin mutants of Arabidopsis thaliana. Ishida T, Kaneko Y, Iwano M, Hashimoto T, Proc Natl Acad Sci USA, 2007 May 15;104(20):8544-9. doi: 10.1073/pnas.0701224104.


An Arabidopsis tubulin mutant with conditional root skewing phenotype. Ishida T, Hashimoto T, J Plant Res, 2007 Sep;120(5):635-40. doi: 10.1007/s10265-007-0105-0. 

 

Twisted growth and organization of cortical microtubules. Ishida T, Thitamadee S, Hashimoto T, J Plant Res, 2007 Jan;120(1):61-70. doi: 10.1007/s10265-006-0039-y.  


その他

Root-knot nematodes modulate cell walls during root-knot formation in Arabidopsis roots. Ishida T*, Suzuki R, Nakagami S, Kuroha T, Sakamoto S, Nakata MT, Yokoyama R, Kimura S, Mitsuda N, Nishitani K, Sawa S, J Plant Res., 2020 May;133(3):419-428. doi: 10.1007/s10265-020-01186-z (*corresponding author)


CLE peptides and their signaling pathways in plant development. Yamaguchi YL, Ishida T*, Sawa S, J Exp Bot, 2016 Aug;67(16):4813-26. doi: 10.1093/jxb/erw208 (*corresponding author) 


BAM 1 and RECEPTOR-LIKE PROTEIN KINASE 2 constitute a signaling pathway and modulate CLE peptide-triggered growth inhibition in Arabidopsis root. Shimizu N#, Ishida T#*, Yamada M, Shigenobu S, Tabata R, Kinoshita A, Yamaguchi K, Hasebe M, Mitsumasu K, Sawa S, New Phytol, 2015 Dec;208(4):1104-13. doi: 10.1111/nph.13520. (#equal contribution; *corresponding author)


Plant peptide hormone signaling. Motomitsu A, Sawa S, Ishida T, Essays in Biochemistry, 2015;58:115-31. doi: 10.1042/bse0580115.


Heterotrimeric G proteins control stem cell proliferation through CLAVATA signaling in Arabidopsis. Ishida T, Tabata R, Yamada M, Aida M, Mitsumasu K, Fujiwara M, Yamaguchi K, Shigenobu S, Higuchi M, Tsuji H, Shimamoto K, Hasebe M, Fukuda H, Sawa S, EMBO Reports, 2014 Nov;15(11):1202-9. doi: 10.15252/embr.201438660. 



（共同研究）

Identification of genes involved in Meloidogyne incognita-induced gall formation processes in Arabidopsis thaliana. Suzuki R, Ueda T, Wada T, Ito M, Ishida T, Sawa S, Plant Biotechnol, 2021 Mar 25;38(1):1-8. doi: 10.5511/plantbiotechnology.20.0716a.


A ClearSee-Based Clearing Protocol for 3D Visualization of Arabidopsis thaliana Embryos. Imoto A, Yamada M, Sakamoto T, Okuyama A, Ishida T, Sawa S, Aida M, Plants, 2021 Jan 20;10(2):190. doi: 10.3390/plants10020190.

 

The atypical E2F transcription factor DEL1 modulates growth–defense tradeoffs of host plants during root-knot nematode infection. Nakagami S, Saeki K, Toda K, Ishida T, Sawa S, Sci Rep, 2020 Jun 1;10(1):8836. doi: 10.1038/s41598-020-65733-3.


Root-knot nematodes induce gall formation by recruiting developmental pathways of post-embryonic organogenesis and regeneration to promote transient pluripotency. Olmo R, Cabrera J, Díaz-Manzano FE, Ruiz-Ferrer V, Barcala M, Ishida T, García A, Andrés MF, Ruiz-Lara S, Verdugo I, Pernas M, Fukaki H, del Pozo JC, Moreno-Risueno MA, Kyndt T, Gheysen G, Fenoll C, Sawa S, Escobar C, New Phytol, 2020 Jul;227(1):200-215. doi: 10.1111/nph.16521

 

AT-Hook Transcription Factors Restrict Petiole Growth by Antagonizing PIFs. Favero DS, Kawamura A, Shibata M, Takebayashi A, Jung JH, Suzuki T, Jaeger KE, Ishida T, Iwase A, Wigge PA, Neff MM, Sugimoto K, Curr Biol,. 2020 Apr 20;30(8):1454-1466.e6. doi: 10.1016/j.cub.2020.02.017


The CLE9/10 secretory peptide regulates stomatal and vascular development through distinct receptors. Qian P, Song W, Yokoo T, Minobe A, Wang G, Ishida T, Sawa S, Chai J, Kakimoto T, Nature Plants, 2018 Dec;4(12):1071-1081. doi: 10.1038/s41477-018-0317-4


Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis roots. Yamaguchi Y, Suzuki R, Cabrera J, Nakagami S, Sagara S, Ejima C, Sano R, Aoki Y, Olmo R, Kurata T, Obayashi T, Demura T, Ishida T, Escobar C, Sawa S, Front. Plant Sci, 2017 Jul 13;8:1195. doi: 10.3389/fpls.2017.01195.


Negative phototaxis in M. incognita. Oota M, Gotoh E, Endo M, Ishida T, Matsushita T, Sawa S, Int J Boil, 2017 May; 9(3): 51-55. doi:10.5539/ijb.v9n3p51


Protocol for root-knot nematode culture by a hydroponic system and nematode inoculation to Arabidopsis. Nishiyama H, Ngan BT, Nakagami S, Ejima C, Ishida T, Sawa S, Nematological Res, 2015 Jul; 45(1): 45-49

 

A plant U-box protein, PUB4, regulates asymmetric cell division and cell proliferation in the root meristem. Kinoshita A, ten Hove CA, Tabata R, Yamada M, Shimizu N, Ishida T, Yamaguchi K, Shigenobu S, Takebayashi Y, Iuchi S, Kobayashi M, Kurata T, Wada T, Seo M, Hasebe M, Blilou I, Fukuda H, Scheres B, Heidstra R, Kamiya Y, Sawa S, Development, 2015 Feb 1;142(3):444-53. doi: 10.1242/dev.113167.


Light-dependent green gall formation induced by Meloidogyne incognita. Nishiyama H, Nakagami S, Todaka A, Arita T, Ishida T, Sawa S, Nematology, 2014 Sep; 16: 889-93. doi: 10.1163/15685411-0000281


特許

特許US 11,142,497 B2 United States Patent, Patent number: US 11,142,497 B2, Plant growth suppression agent, and plant growth suppression method using same, Hayato Ishikawa, Tokio Tani, Shinichiro Sawa, Takashi Ishida, Yusuke Fukushima, Jun Inagaki


特許WO/2018/147290 植物成長抑制剤、およびそれを用いた植物成長抑制方法, 石川勇人, 谷時雄, 澤進一郎, 石田喬志, 福島悠介, 稲垣準


特開WO/2018/147292 植物成長抑制剤、およびそれを用いた植物成長抑制方法, 石川勇人, 谷時雄, 澤進一郎, 石田喬志, 福島悠介, 稲垣準