Multiple Sclerosis

We used structural MRI-based features - GM and WM volume, cortical thickness and gyrification index - to investigate patterns of deficits in MS.

Either Voxel Based Morphometry and Surface Based Morphometry analyses yielded several morphological disease-related changes, which can be used to highlight disease effects in MS.

SVM classification yielded an accuracy of 86,51% (sensitivity 74,58%, specificity 98,44%) with GM volume, while with WM data, SVM correctly classified 82,34% of participants (sensitivity 67,80%, specificity 96,88%).

Soares et al. (2019). DOI: 10.1007/978-3-030-31635-8_202.