PUBLICATIONS

GOOGLE SCHOLAR: Jihoon Ko

 ORCID: https://orcid.org/0000-0002-6555-3728

 H-index: 20 | i10-index: 29 | Total citations: 2,900 (as of Oct. 2025)

 FWCI: 3.57 (Field-Weighted Citation Impact, Scopus via SciVal, 2022–2025)

Manuscripts Currently Under Evaluation

1.  Lee, J.†, Min, J.†, Park, W.†, Hyung, S., Jung, S., Lee, K., Jeon, J., Jeon, N.L., Lee, J.*, Jang, H.R.*, Ko, J.*. High-Throughput Digital Profiling of Tumor-Associated Vascular Networks in Patient-Derived Microphysiological Systems. Science Advances (IF: 12.5, JCR Top 8.5 %) (Under revision).

2.  Lee, Y.†, Kim, S.†, Koh, H., Han, J.Y.*, Ko, J.*. A Tumor Spheroid Array Chip for High-Fidelity Evaluation of Liposomal Drug Delivery Through the EPR Effect. Lab on a Chip (2nd round revision).

3.  Lee, T., Kyung, S.Y., Kwon, M., Park, B.-J., Ko, J.*. Innovations in Skin Microphysiological Systems for Nonclinical Testing and FDA Modernization. Microsystems & Nanoengineering (IF: 9.9, JCR Top 0.6 %) (2nd round revision).

4.  Lee, T., Kyung, S.Y., Park, W., Kwon, M., Park, B.-J., Ko, J.*. Standardized Multi-Modal Microfluidic Skin-on-a-Plate for In Vitro Cosmetic Safety Evaluation. Microsystems & Nanoengineering (IF: 9.9, JCR Top 0.6 %) (Invited submission, under revision).

5.  Ahn, H.†, Min, J.†, Park, W., Park, S., Ko, J.*, Ahn, J.* (Under Revision). A Perfusable Blood Vessel-on-a-Chip Enabling Simultaneous Measurement of Transendothelial Electrical Resistance and Vascular Permeability. Advanced Materials Technologies (Invited submission, under revision).

6.  Ahn, J.†, Mun, S.†, Koo, Y.†, Lee, S., Yang, S.H., Choi, S.H., Mok, J.H., Ahn, J., Cho, S.*, Ko, J.*, Bang, S.*. Stable Tension-Driven Skeletal Muscle Maturation and Functional Quantification on a Monolithic 3D-Printed FORCE Platform. Biomaterials Research (under revision).

Selected Publications

1.      Jung, S., Cheong, S., Lee, Y., Lee, J., Lee, J., Kwon, M.-S., Oh, Y.S., Kim, T., Ha, S., Kim, S.J., Jo, D.H., Ko, J.*, Jeon, N.L.* (2024). Integrating Vascular Phenotypic and Proteomic Analysis in Open Microfluidic Platforms. ACS Nano, 18(36), 24909–24928. (IF: 16.0, JCR Top 6 %)

2.      Ko, J.†, Hyung, S.†, An, M.†, Jung, S., Kim, S.T., Park, S.H., Park, J.O., Lim, H.Y., Kang, W.K., Kim, K.-M., Yoo, S., Jeon, N.L., Lee, J. (2024). Patient-derived tumor spheroid-induced angiogenesis preclinical platform for exploring therapeutic vulnerabilities in cancer. Biomaterials, 307, 122470. (IF: 12.9, JCR Top 3.6 %, FWCI: 3.61)

3.      Ko, J., Park, D., Lee, J., Jung, S., Baek, K., Sung, K.E., Lee, J., Jeon, N.L. (2024). Microfluidic high-throughput 3D cell culture. Nature Reviews Bioengineering, 2(6), 453–469. (FWCI: 4.22, Cited by 47, Selected as Journal Cover)

4.      Hyung, S.†, Ko, J.†, Heo, Y.J., Blum, S.M., Kim, S.T., Park, S.H., Park, J.O., Kang, W.K., Lim, H.Y., Klempner, S.J., Lee, J. (2023). Patient-derived exosomes facilitate therapeutic targeting of oncogenic MET in advanced gastric. Science Advances, 9(47), eadk1098. (IF: 12.5, JCR Top 8.5 %, FWCI: 2.9)

5.      Shin, J.†, Ko, J.†, Jeong, S., Won, P., Lee, Y., Kim, J., Hong, S., Jeon, N.L., Ko, S.H. (2021). Monolithic digital patterning of polydimethylsiloxane with successive laser pyrolysis. Nature Materials, 20(1), 100–107. (IF: 47.656, JCR Top 1.0 %, Cited by 135, Selected as Journal Cover)

Publications

6.      Yi, H.†, Lee, G.†, Park, S., Ha, J., Choi, D., Ko, J.*, Ahn, J.* (2025). Reconstructing the Female Reproductive System Using 3D Bioprinting in Tissue Engineering. Materials Today Bio, 102127. (IF: 10.2, JCR Top 6.9 %)

7.      Kim, M., Yoon, J., Kim, D., Kim, J., Kim, J.S., Go, G., Song, J., Son, S., Park, K., Lee, J., Lee, D., Cho, S., Choi, W., Min, J., Cho, Y.S., Lee, S.J., Yi, H.G., Choi, A., Jeon, S., Lee, H., Choi, D., Han, S., Ko, J., Cho, D.W., Kim, D.S., Jang, J., Kang, H.W. (2025). Advanced Biomanufacturing Technologies for Micro-physiological Systems. International Journal of Precision Engineering and Manufacturing.

8.      Cho, G.-B., Lee, H.-J., Heo, Y.J., Ko, J., Lee, W.-S., Hyung, S. (2025). Tumor-Immune-On-Chip to Evaluate Pathophysiological Feature of T Lymphocytes Expanded from Patient Tumors and Lymph Node Tissues. Cancer Medicine.

9.      Hyung, S.†, Ko, J.†, An, M., Kim, S.T., Park, S.H., Hong, J.Y., Lim, S.H., Kim, K.-M., Lee, J. (2025). Angiogenesis Gene Signatures in Patient-Derived Tumor Spheroids for Genetic and Tumor Angiogenesis Profiling. Journal of Materials Chemistry B, 13, 11597–11610. (Selected as Journal Cover)

10.   Park, W., Kim, C., Ko, J.* (2025). AI-Powered Image Standardization in Microphysiological System Platforms. JMST Advances, 7(3), 163–175.

11.   Lee, T., Min, J., Lee, Y., Ko, J.* (2025). Clinical Potential of Patient-Derived Microphysiological Systems. Journal of the Korean Medical Association, 68(1), 6–8.

12.   Lee, Y.†, Min, J.†, Kim, S.†, Ko, J.* (2025). AI-driven Microphysiological Systems for Advancing Nanoparticle Therapeutics. Advanced Intelligent Systems, 2500022.

13.  Lee, Y.†, Min, J.†, Kim, S., Park, W., Ko, J.*, Jeon, N.L.* (2025). Recapitulating the Cancer-Immunity Cycle on a Chip. Advanced Healthcare Materials, e2401927. (IF: 9.6, JCR Top 8.5%)

14.   Ko, J., Hyung, S., Cheong, S., Jeon, N.L.* (2024). Revealing the Clinical Potential of High-Resolution Organoids. Advanced Drug Delivery Reviews, 201, 115202. (IF: 17.6, JCR Top 1.0%)

15.  Park, S., Kim, Y., Lee, J., Jung, S., Hong, J., Kim, S., Lee, S.-R., Song, J., Park, S., Oh, Y.S., Ko, J., Jeon, N.L. (2024). Flow-IMPACT: A Pumpless, High-Throughput 3D Cell Culture Platform for Investigation of Synergistic Angiogenic Effects. Advanced Materials Technologies, 10(11) 2401526. (Selected as Journal Cover)

16.   Ko, J.*, Song, J., Lee, Y., Choi, N., Kim, H.* (2024). Understanding Organotropism in Cancer Metastasis Using Microphysiological Systems. Lab on a Chip, 24, 1542–1556.

17.   Lee, J.†, Kim, S.†, Ko, J.†, Park, S., Lee, S.R., Kim, Y., Kim, W., Chung, Y., Kwon, O.H., Jeon, N.L.‡ (2024). Angio-Net: Deep Learning-based Label-free Detection and Morphometric Analysis of In Vitro Angiogenesis. Lab on a Chip, 24, 751–763.

18.   Lee, J., Jung, S., Hong, H.K., Jo, H., Rhee, S., Jeong, Y.L., Ko, J., Cho, Y.B., Jeon, N.L. (2024). Vascularized Tissue Mesh-Assisted Platform (VT-MAP) for the Personalized Drug Screening of Colorectal Cancer Organoids. Lab on a Chip, 24, 2208-2223.

19.   Ko, J.*, Song, J., Choi, N., Kim, H.N. (2023). Patient-Derived Microphysiological Systems for Precision Medicine. Advanced Healthcare Materials, 13(7), e2303161. (IF: 10.0, JCR Top 4.7%, Selected as Journal Cover)

20.   Lee, W., Yoon, B., Lee, J., Jung, S., Oh, Y.S., Ko, J.*, Jeon, N.L.* (2023). Machine Learning-Aided Three-Dimensional Morphological Quantification of Angiogenic Vasculature in the Multiculture Microfluidic Platform. BioChip Journal, 17(3), 357–368.

21.   Song, J.†, Ko, J.†, Choi, N., Jeon, N.L., Kim, H.N. (2023). Tumor Spheroid-Based and Microtumor-Based Vascularized Models for Replicating the Vascularized Tumor Microenvironment. Organoid, 3, e6.

22.   Jung, J., Kim, S.T., Ko, J., Hong, J.Y., Park, J.O., Ha, S.Y., Lee, J. (2023). Clinical Implication of HER2 Aberration in Patients With Metastatic Cancer Using Next-Generation Sequencing: A Pan-Tumor Analysis. JCO Precision Oncology, 7, e2200537.

23.   Park, S., Kim, Y., Ko, J., Song, J., Lee, J., Hong, Y.K., Jeon, N.L. (2023). One-Step Achievement of Tumor Spheroid-Induced Angiogenesis in a High-Throughput Microfluidic Platform: One-Step Tumor Angiogenesis Platform. Organoid, 3, e3.

24.   Ko, J.†, Jung, J.†, Kim, S.T., Hong, J.Y., Park, S., Park, J.O., Park, Y.S., Lim, H.Y., Ahn, S., Kim, K.-M., Kang, W.K., Lee, J. (2022). MET Gene Alterations Predict Poor Survival Following Chemotherapy in Patients with Metastatic Cancer. Pathology and Oncology Research, 28, 1610697. 

25.   Ko, J., Park, D., Lee, S., Gumuscu, B., Jeon, N.L. (2022). Engineering Organ-on-a-Chip to Accelerate Translational Research. Micromachines, 13(8), 1200.

26.   Kim, Y.†, Ko, J.†, Shin, N., Park, S., Lee, S.R., Kim, S., Song, J., Lee, S., Kang, K.-S., Lee, J., Jeon, N.L. (2022). All-in-One Microfluidic Design to Integrate Vascularized Tumor Spheroid into High-Throughput Platform. Biotechnology and Bioengineering, 119(12), 3678-3693.

27.   Leung, C.M., Haan, P., Ronaldson-Bouchard, K., Kim, G.-A., Ko, J., Rho, H.S., Chen, Z., Habibovic, P., Jeon, N.L., Takayama, S., Shuler, M.L., Vunjak-Novakovic, G., Frey, O., Verpoorte, E., Toh, Y.-C. (2022). A Guide to the Organ-on-a-Chip. Nature Reviews Methods Primers, 2, 33. (IF: 56.0, JCR Top 0.4 %, FWCI: 33.61, Cited by 1,002)

28.   Ahn, J., Kim, D.H., Koo, D.J., Lim, J., Park, T.E., Lee, J., Ko, J., Kim, S., Kim, M., Kang, K.S., Kim, S.Y., Kim, Y., Jeon, N.L. (2022). 3D Microengineered Vascularized Tumor Spheroids for Drug Delivery and Efficacy Testing. Acta Biomaterialia, 165, 153-167.

29.   Shin, N., Kim, Y., Ko, J., Choi, S.W., Hyung, S., Lee, S.E., Park, S., Song, J., Jeon, N.L., Kang, K.S. (2022). Vascularization of iNSC Spheroid in a 3D Spheroid-on-a-Chip Platform Enhances Neural Maturation. Biotechnology and Bioengineering, 119(9), 2256–2268.

30.   Lee, B., Kim, S., Ko, J., Lee, S.R., Kim, Y., Park, S., Kim, J., Hyung, S., Kim, H.Y., Jeon, N.L. (2022). 3D Micromesh-Based Hybrid Bioprinting: Multidimensional Liquid Patterning for 3D Microtissue Engineering. NPG Asia Materials, 14, 6.

31.   Lee, S.Y.†, Byeon, S.†, Ko, J.†, Hyung, S., Lee, I.K., Jeon, N.L., Hong, J.Y., Kim, S.T., Park, S.H., Lee, J. (2021). Reducing Tumor Invasiveness by Ramucirumab and TGF-β Receptor Kinase Inhibitor in a Diffuse-Type Gastric Cancer Patient-Derived Cell Model. Cancer Medicine, 10(20), 7253–7262.

32.   Kim, S.†, Ko, J.†, Lee, S.R., Park, D., Park, S., Jeon, N.L. (2021). Anchor-IMPACT: A Standardized Microfluidic Platform for High-Throughput Anti-Angiogenic Drug Screening. Biotechnology and Bioengineering, 118(6), 2524–2535.

33.   Jusoh, N.†, Ko, J.†, Jeon, N.L. (2019). Microfluidics-Based Skin Irritation Test Using In Vitro 3D Angiogenesis Platform. APL Bioengineering, 3(3), 036101.

34.   Ko, J.†, Ahn, J.†, Kim, S., Lee, Y., Lee, J., Park, D., Jeon, N.L. (2019). Tumor Spheroid-on-a-Chip: A Standardized Microfluidic Culture Platform for Investigating Tumor Angiogenesis. Lab on a Chip, 19, 2822–2833.

35.   Ko, J., Lee, Y., Lee, S., Lee, S.R., Jeon, N.L. (2019). Human Ocular Angiogenesis-Inspired Vascular Models on an Injection-Molded Microfluidic Chip. Advanced Healthcare Materials, 8(15):e1900328. (IF: 7.4, JCR Top 7.5%, Selected as Journal Cover)

36.   Lee, S.R., Hyung, S., Bang, S., Lee, Y., Ko, J., Lee, S., Kim, H.J., Jeon, N.L. (2019). Modeling Neural Circuit, Blood–Brain Barrier, and Myelination on a Microfluidic 96-Well Plate. Biofabrication, 11(3), 035013.

37.   Park, D., Son, K., Hwang, Y., Ko, J., Lee, Y., Doh, J., Jeon, N.L. (2019). High-Throughput Microfluidic 3D Cytotoxicity Assay for Cancer Immunotherapy. Frontiers in Immunology, 10, 1133.

38.   Ahn, J., Ko, J., Lee, S., Yu, J., Kim, Y.T., Jeon, N.L. (2018). Microfluidics in Nanoparticle Drug Delivery; From Synthesis to Pre-Clinical Screening. Advanced Drug Delivery Reviews, 128, 29–53. (IF: 15.5, JCR Top 0.9 %, Cited by 245)

39.   Lee, S., Ko, J., Park, D., Lee, S.R., Chung, M., Lee, Y., Jeon, N.L. (2018). Microfluidic-Based Vascularized Microphysiological Systems. Lab on a Chip, 18(18), 2686-2709.

40.   Park, D., Kang, M., Choi, J.W., Paik, S.M., Ko, J., Lee, S., Lee, Y., Son, K., Ha, J., Choi, M., Park, W., Kim, H.Y., Jeon, N.L. (2018). Microstructure Guided Multi-Scale Liquid Patterning on an Open Surface. Lab on a Chip, 18(14), 2013-2022.

41.   Bang, S., Lee, S.R., Ko, J., Son, K., Tahk, D., Ahn, J., Im, C., Jeon, N.L. (2017). A Low Permeability Microfluidic Blood-Brain Barrier Platform with Direct Contact Between Perfusable Vascular Network and Astrocytes. Scientific Reports.

42.   Oh, S., Ryu, H., Tahk, D., Ko, J., Chung, Y., Lee, H.K., Lee, T.R., Jeon, N.L. (2017). Open-Top Microfluidic Device for In Vitro Three-Dimensional Capillary Beds. Lab on a Chip, 17(20), 3405-3414.