PUBLICATIONS

GOOGLE SCHOLAR: Jihoon Ko

ORCID: 0000-0002-6555-3728

Selected Publications

1. S. Jung, S. Cheong, Y. Lee, J. Lee, J. Lee, M-S. Kwon, Y.S. Oh, T. Kim, S. Ha, S.J. Kim, D.H. Jo, J. Ko†, N.L. Jeon†, “Integrating Vascular Phenotypic and Proteomic Analysis in Open Microfluidic Platforms”, ACS Nano (2024) [LINK]

2. J. Ko†. S. Hyung†, M. An†, S. Jung, S.T. Kim, S.H. Park, J.O. Park, H.Y. Lim, W.K. Kang, K-M. Kim, S. Yoo, N.L. Jeon, J. Lee, “Patient-derived tumor spheroid-induced angiogenesis preclinical platform for exploring therapeutic vulnerabilities in cancer”, Biomaterials (2024) [LINK]

3. J. Ko, D. Park, J. Lee, S. Jung, J. Lee, K. Sung, K. Baek, N.L. Jeon, "Microfluidic High- throughput 3D Cell Culture", Nature Reviews Bioengineering (2024) [LINK]

4. S. Hyung†, J. Ko†, Y.J. Heo, S.M Blum, S.T. Kim, S.H. Park, J.O. Park, W.K. Kang, H.Y. Lim, S.J. Klempner, J. Lee, “Patient-derived exosomes facilitate therapeutic targeting of oncogenic MET in advanced gastric cancer”, Science Advances (2023) [LINK]

5. J. Shin†, J. Ko†, S. Jeong, P. Won, Y. Lee, J. Kim, S. Hong, N.L. Jeon, S.H. Ko, “Monolithic digital patterning of polydimethylsiloxane with successive laser pyrolysis”, Nature Materials (2021) [LINK]
   

Full Publications

6. M. Kim, J. Yoon, D. Kim, J. Kim, J. S. Kim, G. Go, J. Song, S. Son, K. Park, J. Lee, D. Lee, S. Cho, W. Choi, J. Min, Y.S. Cho, S.J. Lee, H.G. Yi, A. Choi, S. Jeon, H. Lee, D. Choi, S. Han, J. Ko, D.W. Cho, D.S. Kim, J. Jang, H.W. Kang, "Advanced Biomanufacturing Technologies for Micro-physiological Systems", International Journal of Precision Engineering and Manufacturing (2025)

7. G.-B. Cho, H.-J Lee, Y.J. Heo, J. Ko, W.-S. Lee, S. Hyung, "Tumor-Immune-On-Chip to Evaluate Pathophysiological Feature of T Lymphocytes Expanded from Patient Tumors and Lymph Node Tissues", Cancer Medicine (2025)

8. S. Hyung†, J. Ko†, M. An, S.T. Kim, S.H. Park, J.Y. Hong, S.H. Lim, K-M. Kim, J. Lee, "Angiogenesis Gene Signatures in Patient-Derived Tumor Spheroids for Genetic and Tumor Angiogenesis Profiling", Journal of Materials Chemistry B (2025)

9. H. Yi*, G. Lee*, S. Park, J. Ha, D. Choi, J. Ko†, J. Ahn†, "Reconstructing the Female Reproductive System Using 3D Bioprinting in Tissue Engineering", Materials Today Bio (2025)

10. W. Park, C. Kim, J. Ko, "AI-Powered Image Standardization in Microphysiological System Platforms", JMST Advances (2025)

11. T. Lee, J. Min, Y. Lee, J. Ko, "Clinical Potential of Patient-Derived Microphysiological Systems", JKMA (2025)

12. Y. Lee†, J. Min†, S. Kim†, J. Ko, "AI-driven Microphysiological Systems for Advancing Nanoparticle Therapeutics", Advanced Intelligent Systems (2025)

13. S. Park, Y. Kim, J. Lee, S. Jung, J. Hong, S. Kim, S‐R. Lee, J. Song, S. Park, Y. S. Oh, J. Ko, N. L. Jeon, "Flow‐IMPACT: A Pumpless, Hight‐Throughput 3D Cell Culture Platform for Investigation of Synergistic Angiogenic Effects", Advanced Materials Technologies (2025)

14. Y. Lee†, J. Min†, S. Kim, W. Park, J. Ko†, N.L. Jeon† “Recapitulating the cancer-immunity cycle on a chip", Advanced Healthcare Materials (2025)

15.  J. Ko, S. Hyung, S. Cheong, N.L. Jeon‡, "Revealing the Clinical Potential of High- Resolution Organoids", Advanced Drug Delivery Reviews (2024)

16.  J. Ko†‡, J. Song†, Y. Lee, N. Choi, H. Kim‡, "Understanding Organotropism in Cancer Metastasis Using Microphysiological Systems", Lab on a Chip (2024)

17.  J. Lee†, S. Kim†, J. Ko†, S. Park, S.R. Lee, Y. Kim, W. Kim, Y. Chung, O.H. Kwon, N.L. Jeon‡, "Angio-Net: Deep Learning-based Label-free Detection and Morphometric Analysis of In Vitro Angiogenesis", Lab on a Chip (2024)

18.  J. Lee, S. Jung, HK. Hong, H. Jo, S. Rhee, YL. Jeong, J. Ko, YB. Cho, NL. Jeon, “Vascularized tissue mesh-assisted platform (VT-MAP) for the personalized drug screening of colorectal cancer organoids”, Lab on a Chip (2024)

19.  J. Ko, J. Song, N. Choi, HN. Kim, "Patient-Derived Microphysiological Systems for Precision Medicine", Advanced Healthcare Materials (2023) 

20.  W Lee, B Yoon, J Lee, S Jung, YS Oh, J Ko†, NL Jeon†, “Machine Learning-Aided Three- Dimensional Morphological Quantification of Angiogenic Vasculature in the Multiculture Microfluidic Platform”, BioChip Journal (2023)

21.  J Jung, ST Kim, J Ko, JY Hong, JO Park, SY Ha, J Lee, “Clinical Implication of HER2 Aberration in Patients With Metastatic Cancer Using Next-Generation Sequencing: A Pan-Tumor Analysis”, JCO Precision Oncology (2023)

22.  J Song†, J Ko†, N Choi, NL Jeon, HN Kim, “Tumor spheroid-based and microtumor- based vascularized models for replicating the vascularized tumor microenvironment” Organoid (2023)

23.  S Park, Y Kim, J Ko, J Song, J Lee, YK Hong, NL Jeon, “One-step achievement of tumor spheroid-induced angiogenesis in a high-throughput microfluidic platform: one-step tumor angiogenesis platform”, Organoid (2023)

24.  J. Ko†, J. Jung†, S.T. Kim, J.Y. Hong, S. Park, J.O. Park, Y.S. Park, H.Y. Lim, S. Ahn, K-M. Kim, W.K. Kang, J Lee, “MET gene alterations predicts poor survival following chemotherapy in patients with metastatic cancer.” Pathology and Oncology Research (2022) (IF: 3.201)

25.  C.M. Leung, P. Haan, K. Ronaldson-Bouchard, G-A.Kim, J. Ko, H.S. Rho, Z. Chen, P. Habibovic, N.L. Jeon, S. Takayama, M. L. Shuler, G. Vunjak-Novakovic, O. Frey, E. Verpoorte, Y-C. Toh, “A Guide to the Organ-on-a-Chip”, Nature Reviews Methods Primers (2022) 

26.  J. Ko, D. Park, S. Lee, B. Gumuscu, N. L. Jeon, “Engineering Organ-on-a-Chip to Accelerate Translational Research”, Micromachines (2022) (IF: 3.523)

27.  J. Ahn, DH. Kim, DJ. Koo, J. Lim, TE. Park, J. Lee, J. Ko, S. Kim, M. Kim, KS. Kang, SY. Kim, Y. Kim, NL. Jeon, “3D microengineered vascularized tumor spheroids for drug delivery and efficacy testing”, Acta Biomaterialia (2022) (IF: 10.633)

28.   Y. Kim†, J. Ko†, N. Shin, S. Park, S.R. Lee, S. Kim, J. Song, S. Lee, K-S. Kang, J. Lee, N.L. Jeon, “All-in-One microfluidic design to integrate vascularized tumor spheroid into high- throughput platform” Biotechnology and Bioengineering (2022) (IF: 4.395)

29.  SY. Lee†, S. Byeon†, J. Ko†, S. Hyung, IK. Lee, N.L. Jeon, J.Y. Hong, S.T. Kim, S.H. Park, J. Lee, “Reducing tumor invasiveness by ramucirumab and TGF-β receptor kinase inhibitor in a diffuse-type gastric cancer patient-derived cell model” Cancer Medicine, (2021) (IF: 4.711)

30.  S. Kim†, J. Ko†, S.R. Lee, D. Park, S. Park, N.L. Jeon, “Anchor-IMPACT: A Standardized Microfluidic Platform for High-throughput Anti-angiogenic Drug Screening” Biotechnology and Bioengineering (2021) (IF: 4.395)

31.  N. Jusoh†, J. Ko†, N.L. Jeon, “Microfluidics-based skin irritation test using in vitro 3D angiogenesis platform”, APL Bioengineering (2019) (IF: 6.268)

32. J. Ko, Y. Lee, S. Lee, S.R. Lee, N.L. Jeon, “Human Ocular Angiogenesis-Inspired Vascular Models on an Injection-Molded Microfluidic Chip”, Advanced Healthcare Materials (2019) (IF: 11.092) (Cover selected)

33.  J. Ko†, J. Ahn†, S. Kim, Y. Lee, J. Lee, D. Park, N.L. Jeon, “Tumor spheroid-on-a-chip: a standardized microfluidic culture platform for investigating tumor angiogenesis”, Lab on a Chip (2019) (IF: 7.517) (Cover selected)

34.  N. Shin, Y. Kim, J. Ko, S.W. Choi, S. Hyung, SE. Lee, S. Park, J. Song, N.L. Jeon, KS. Kang, “Vascularization of iNSC spheroid in a 3D spheroid-on-a-chip platform enhances neural maturation” Biotechnology and Bioengineering (2022) (IF: 4.395)

35.  B. Lee, S. Kim, J. Ko, SR. Lee, Y. Kim, S. Park, J. Kim, S. Hyung, HY. Kim, N.L. Jeon, “3D micromesh-based hybrid bioprinting: multidimensional liquid patterning for 3D microtissue engineering” NPG Asia Materials (2022) (IF: 10.990)

36.  S.R. Lee, S. Hyung, S. Bang, Y. Lee, J. Ko, S. Lee, H.J. Kim, N.L. Jeon, “Modeling neural circuit, blood–brain barrier, and myelination on a microfluidic 96 well plate”, Biofabrication (2019) (IF: 11.061)

37.  D. Park, K. Son, Y. Hwang, J. Ko, Y. Lee, J. Doh, N.L. Jeon, “High-throughput microfluidic 3D cytotoxicity assay for cancer immunotherapy”, Frontiers in Immunology (2019) (IF: 8.786)

38.  J. Ahn, J. Ko, S. Lee, J. Yu, Y.T. Kim, N.L. Jeon, “Microfluidics in nanoparticle drug delivery; From synthesis to pre-clinical screening”, Advanced Drug Delivery Reviews (2018) (IF: 17.873)

39.  S. Lee, J. Ko, D. Park, S.R. Lee, M. Chung, Y. Lee, N.L. Jeon, “Microfluidic-based vascularized microphysiological systems”, Lab on a Chip (2018) (IF: 7.517)

40.  D. Park, M. Kang, J.W. Choi, S.M. Paik, J. Ko, S. Lee, Y. Lee, K. Son, J. Ha, M. Choi, W. Park, H.Y. Kim, N.L. Jeon, “Microstructure guided multi-scale liquid patterning on an open surface”, Lab on a Chip (2018) (IF: 7.517)

41.  S. Bang, S.R. Lee, J. Ko, K. Son, D. Tahk, J. Ahn, C. Im, N.L. Jeon, “A low permeability microfluidic blood-brain barrier platform with direct contact between perfusable vascular network and astrocytes”, Scientific reports (2017) (IF: 4.996)

42.  S. Oh, H. Ryu, D. Tahk, J. Ko, Y. Chung, H.K. Lee, T.R. Lee, N.L. Jeon, ““Open-top” microfluidic device for in vitro three-dimensional capillary beds”, Lab on a Chip (2017) (IF: 7.517)