Students who are eager to delve into cutting-edge neuroscience research are encouraged to reach out to inquire about at ylee@kookmin.ac.kr
Step into the Gateway of Discovery – Welcome to the Intelligence Genetics Lab at Kookmin University, Seoul, South Korea
Our research investigates how pharyngeal gustatory receptor neurons (GRNs) in fruit flies detect and respond to high salt levels. We identified that the ionotropic receptor Ir60b is crucial for this process. Ir60b, along with coreceptors IR25a and IR76b, is essential in preventing excessive salt consumption. Read more...
Our study highlights cantharidin's hazardous impact on survival and visceral integrity, shedding light on its toxic properties. Our study highlights cantharidin's hazardous impact on survival and visceral integrity, shedding light on its toxic properties. Read More ...
Our Study proves that vitamin C doubles starvation resistance and induces egg-laying in Drosophila melanogaster. Our behavioral analyses of genetically engineered and anatomically ablated flies show that fruit flies sense vitamin C via sweet‐sensing gustatory receptor neurons in the labellum. Read More ...
Here, we demonstrated that eight amino acids, including arginine, glycine, alanine, serine, phenylalanine, threonine, cysteine, and proline, differentially stimulate feeding behavior by activating sweet-sensing gustatory receptor neurons (GRNs) in L-type and S-type sensilla. In turn, this process is mediated by three GRs (GR5a, GR61a, and GR64f), as well as two broadly required ionotropic receptors (IRs), IR25a and IR76b. However, GR5a, GR61a, and GR64f are only required for sensing amino acids in the sweet-sensing GRNs of L-type sensilla. Read More ...